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Phytanic acid

Name: Phytanic acid
Brand: Cuicheng Bio
SKU: pr2606081184
Price: 60000 USD
Availability: InStock

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Unit Price:

$60000-70000/G FOB

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CAS No.:

14721-66-5

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

10mg

Price valid (until):

2026-07-08

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
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Inquiry History

Description

Phytanic acid (systematically known as 3,7,11,15-tetramethylhexadecanoic acid) functions primarily as a peroxisomal metabolic substrate, a nuclear receptor activator (transcriptional regulator), a clinical biomarker for rare metabolic diseases, and a dietary tracer.

It is a branched-chain fatty acid derived from the metabolism of phytol, a component of chlorophyll. Because humans cannot synthesize it natively, it is obtained exclusively through dietary sources like ruminant fats (beef, lamb), dairy products, and certain fish.

Core Functions and Biological Roles

Substrate for Peroxisomal α-Oxidation: Because phytanic acid possesses a methyl group at its C-3 (β) position, standard β-oxidation enzymes cannot degrade it due to steric hindrance. To bypass this obstacle, it must be localized to the peroxisomes, where the enzyme phytanoyl-CoA hydroxylase (PhyH) initiates α-oxidation. This pathway removes a single carbon atom, converting it into pristanic acid, which can then undergo standard β-oxidation.
Nuclear Receptor Activator (Transcriptional Control): Inside cells, phytanic acid and its metabolites act as potent lipid signaling molecules. It binds to and activates the Peroxisome Proliferator-Activated Receptor alpha (PPARα) and the Retinoid X Receptor (RXR). This activation directly modulates the transcription of genes regulating lipid transport, fatty acid oxidation, and systemic glucose homeostasis.
Diagnostic Marker for Refsum Disease: In clinical medicine, it serves as the definitive biomarker for Refsum disease, a rare autosomal recessive disorder. Patients with this condition have mutated PHYH genes, rendering them unable to perform α-oxidation. Consequently, dietary phytanic acid accumulates to toxic levels in tissues, leading to severe neurological symptoms like retinitis pigmentosa, cerebellar ataxia, peripheral neuropathy, and hearing loss.
Dietary and Epidemiological Biomarker: In nutritional science, plasma levels of phytanic acid are used as a reliable biomarker to quantify the consumption of red meat and full-fat dairy products. Furthermore, its accumulation is heavily studied in oncology and metabolic research due to its correlations with mitochondrial oxidative stress and insulin resistance.

Basic Info

Product Name:

Phytanic acid

Other Name:

Hexadecanoic acid,3,7,11,15-tetramethyl-;Phytanic acid;3,7,11,15-Tetramethylhexadecanoic acid;Phytanoic acid;NSC 108698;2258-05-1;18717-98-1

CAS No.:

14721-66-5

Molecular Formula:

C20H40O2

InChIKeys:

InChIKey=RLCKHJSFHOZMDR-UHFFFAOYSA-N

Molecular Weight:

312.53

Exact Mass:

312.53

NSC Number:

108698

HScode:

2915900090

Categories:

Food Safety

Characteristics

PSA:

37.3

XLogP3:

8.54

Appearance:

Liquid

Density:

0.8761 g/cm³ @ Temp: 20 °C

Melting Point:

<-10 °C

Boiling Point:

221 °C @ Press: 7.5 Torr

Flash Point:

179.7±11.2 °C

Refractive Index:

1.4461 (estimate)

Water Solubility:

0.001092 mg/L @ 25 °C (est)

Storage Conditions:

2-8°C

Collision Cross Section:

183.17 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]

See More Phytanic acid Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Phytanic acid Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Year of Establishment:
2019

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Vietnam	PHYTANIC ACID	100 KG	Dec 13, 2023

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Phytanic acid

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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