Buy High Quality Pharmaceutical Grade Phosphatidylserine Raw Material Powder CAS 51446-62-9

I. Overview

Phosphatidylserine (PS) is a naturally occurring phospholipid critical for cellular membrane structure and function, particularly abundant in brain cell membranes, accounting for approximately 10%–20% of mammalian brain phospholipids. Its chemical structure consists of a glycerol backbone, a serine residue, and two fatty acid chains, forming an amphiphilic molecule with hydrophilic and hydrophobic domains. PS is widely distributed in bacteria, yeast, plants, and mammalian cells, serving as a key active component of cell membranes essential for maintaining membrane fluidity, permeability, and signal transduction.

II. Applications

1. Pharmaceutical and Health Fields

• Neuroprotection and Cognitive Enhancement
  Dubbed "brain gold," PS enhances neuronal membrane fluidity, promotes neurotransmitter (e.g., acetylcholine) release, and improves memory and learning capacity. Clinical studies demonstrate that PS supplementation significantly enhances cognitive function in Alzheimer's disease patients, delays brain atrophy, and alleviates neurodegenerative decline. Additionally, PS modulates the dopamine system to reduce tic frequency in children with Tourette syndrome and mitigate ADHD symptoms.
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• Mood Regulation and Stress Reduction
  PS inhibits cortisol (stress hormone) secretion, attenuates stress responses, and alleviates mood disorders such as depression and anxiety. By regulating the hypothalamic-pituitary-adrenal (HPA) axis, PS stabilizes emotional states, making it suitable for stress-prone populations and adjunctive depression therapy.
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• Anti-inflammatory and Immunomodulatory Effects
  During apoptosis, PS externalizes to the cell membrane, acting as an "eat-me" signal for macrophage recognition and facilitating apoptotic cell clearance. This property has inspired PS-based targeted drug delivery systems to enhance tumor-specific cytotoxicity. PS also modulates immune cell activity, suppresses pro-inflammatory cytokine release, and mitigates neuroinflammation.

2. Food and Nutraceutical Industries

• Functional Food Additive
  As a natural emulsifier, PS uniformly disperses lipids, improving food texture and stability. Approved by the EU and FDA as a dietary supplement, PS is incorporated into dairy products, baked goods, and beverages to enhance nutritional value. For example, PS-fortified milk significantly boosts memory performance.
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• Anti-Aging and Brain Health Supplements
  PS reduces oxidative stress-induced neuronal damage through antioxidant mechanisms, protecting brain cells. Formulated into capsules, gummies, and other supplements, PS prevents age-related cognitive decline, enhances brain function in the elderly, and supports learning and memory in adolescents.

3. Cosmetic Applications

• Skin Repair and Anti-Aging
  PS promotes collagen synthesis, enhances skin elasticity, and reduces wrinkles and fine lines. Its moisturizing properties strengthen the skin barrier, prevent water loss, and protect against free radical damage. As an emulsifier, PS stabilizes cosmetic formulations and improves product application.

4. Feed Industry

• Enhanced Animal Performance
  PS as a feed additive stimulates appetite, improves feed conversion efficiency, and increases weight gain and productivity. Its fatty acid content supports gut health, enhances immunity, and reduces disease incidence. Additionally, PS improves feed texture and overall quality as an emulsifier.

5. Drug Delivery Systems

• Targeted Drug Carriers
  Leveraging PS enrichment on apoptotic cell membranes, researchers have developed PS-modified liposomes for macrophage-targeted drug delivery. For instance, conjugating PS with liposomal chemotherapy drugs enhances tumor tissue accumulation and reduces systemic toxicity. Such nanodelivery systems show promise in cancer therapy.
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• Company Profile
  

• Packing: 

  1. Weight <1kg ---- Fluorinated bottle 

  2. 25kg ---- Plastic bucket

  3. 180- 200kg ---- Drum

  P.S.: we accept packaging customization.

  Delivery:  

  We have large quantity raw powder in stock, normally could ship out within 3 working days. 

  For rush delivery, please contact our sales team for particular arrangement.

  Shipping:

  We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.

  Shipping details & shipping documents will be provided and sent to customers as long as it is ready.

  We keep tracking the shippment until clients well received.

  After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.