 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > GS-441524 for Sale > Alprostadil 99% Pharmaceutical Grade High Purity Factory Supply Hot selling

Alprostadil 99% Pharmaceutical Grade High Purity Factory Supply Hot selling buy - large image1

Alprostadil 99% Pharmaceutical Grade High Purity Factory Supply Hot selling buy - image1

Alprostadil 99% Pharmaceutical Grade High Purity Factory Supply Hot selling buy - image2

Alprostadil 99% Pharmaceutical Grade High Purity Factory Supply Hot selling buy - image3

Alprostadil 99% Pharmaceutical Grade High Purity Factory Supply Hot selling buy - image4

Alprostadil 99% Pharmaceutical Grade High Purity Factory Supply Hot selling

Name: Alprostadil 99% Pharmaceutical Grade High Purity Factory Supply Hot selling
Brand: Pharma;Conutrix
SKU: pr2606171374
Price: 33 USD
Availability: InStock

TDS 42 Inquiries

Unit Price:

$33/UNIT FOB

Get Latest Price 

CAS No.:

1191237-69-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

tianjin

Brand:

Pharma;Conutrix

Packaging:

10 vials/box

Price valid (until):

2026-10-14

Contact Supplier

 Chat Now

Anhui Ruibang Trading Co., Ltd

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

 Visit Store

Product Description
Seller Information
Inquiry History

Description
Product Detail
1. Product Overview

Alprostadil, also known as Prostaglandin E1 (PGE1), is a high-purity synthetic bioactive prostaglandin molecule with pharmaceutical-grade specifications. Though not a traditional amino-acid peptide, it exhibits peptide-like high biological activity and precise signaling regulation, widely classified as a specialty therapeutic biomolecule. Produced via standardized synthetic processes with ≥99% HPLC purity, this stable small-molecule compound features ultra-high biological availability, consistent batch repeatability and low systemic irritation. As a potent EP receptor agonist, Alprostadil specializes in vascular dilation, microcirculation activation, smooth muscle relaxation and anti-platelet aggregation. It is extensively applied in vascular function research, peripheral circulation repair, microvascular lesion conditioning and high-end pharmaceutical raw material formulation development.

2. Basic Specifications

Product Name: Alprostadil Pharmaceutical Grade

Full Name: Prostaglandin E1 (PGE1)

CAS Number: 745-65-3

Molecular Weight: 354.48 Da

Purity: ≥99.0% (HPLC)

Appearance: White sterile lyophilized powder

Solubility: Soluble in sterile water and aqueous solvent

Core Feature: Potent microcirculation activator & vascular smooth muscle regulator

Grade Standard: Pharmaceutical raw material grade, low endotoxin, heavy metal compliant

Storage: -20°C sealed, dry and protected from light

Shelf Life: 24 months under standard storage conditions

3. Mechanism of Action

Alprostadil exerts targeted vascular and tissue regulation by selectively binding to EP prostanoid receptors distributed on vascular smooth muscle, endothelial cells and peripheral tissues. It activates intracellular adenylate cyclase, elevates cAMP levels and reduces intracellular calcium concentration, triggering continuous vascular smooth muscle relaxation and systemic microvascular dilation. Meanwhile, it effectively inhibits platelet adhesion and aggregation, improves blood rheology, and eliminates microcirculation stasis and hypoxic damage.

Different from common vasodilators with transient efficacy, Alprostadil delivers dual vascular protection and metabolic optimization. It repairs damaged vascular endothelial function, improves peripheral tissue oxygen and nutrient supply, blocks inflammatory cascades caused by microcirculation disorders, and achieves long-term stabilization of vascular physiological function without endocrine disturbance or drug resistance.

4. Core Benefits & Applications

Microcirculation Activation: Dilates peripheral microvessels, improves blood flow velocity, relieves tissue ischemia and hypoxia, and repairs microcirculation dysfunction caused by aging and vascular sub-health.

Vascular Endothelial Repair: Protects vascular endothelial cells, reduces endothelial inflammatory damage, improves vascular elasticity, and delays peripheral vascular tissue degeneration.

Anti-Thrombotic & Blood Regulation: Inhibits abnormal platelet aggregation, optimizes blood rheological properties, and reduces the risk of microvascular stasis and occlusion.

Smooth Muscle Regulation: Relaxes cavernosal and peripheral smooth muscle, improves local blood perfusion, and supports physiological tissue function recovery.

Professional Research Use: High-purity API for vascular pharmacology, microcirculation mechanism research, endothelial repair study and pharmaceutical formulation development.

5. Advantages of 99% Pharmaceutical-Grade Alprostadil

Precise EP receptor targeting: Specific binding to prostanoid receptors, accurate vascular regulation with minimal systemic side effects

Dual dilation & repair efficacy: Combines rapid microcirculation activation and long-term endothelial repair, superior to single-effect vasodilators

Small-molecule high permeability: Ultra-low molecular weight ensures fast tissue penetration and high bioavailability

≥99% HPLC ultra-high purity, strict single impurity control, zero batch difference for synthetic prostaglandin biomolecule

Low endotoxin and ultra-low heavy metals, fully compliant with pharmaceutical raw material standards, stable activity and formulation compatibility

6. Safety & Usage Features

Alprostadil is a high-safety pharmaceutical biomolecule with reliable biological tolerance. It features mild physiological vascular regulation, no hormone interference, no cumulative toxicity and no drug dependence. Standard cyclic use safely optimizes microcirculation, repairs endothelial damage and improves tissue hypoxia status, suitable for long-term vascular sub-health conditioning and high-standard biomedical research applications.
Items Specifications

About us

Anhui Ruibang Trading Co., Ltd. was established with a clear mission: to simplify international trade for businesses of all sizes. We act as a bridge between manufacturers and global buyers, offering professional sourcing, quality inspection, order coordination, and logistics management.

Our team brings years of experience in cross-border trade, supplier networks, and export documentation. We understand the challenges of international business — language barriers, quality control, shipping complexities — and we solve them with a client-first approach.

At Ruibang Trading, we don’t just move goods; we build relationships. Whether you are looking for a reliable supplier, need help consolidating shipments, or want to expand your product line, we provide tailored solutions to meet your goals.

Our Commitment: Integrity, efficiency, and transparency in every transaction.

Why choose us

As a professional original peptide manufacturer integrating independent R&D, production and sales, we stand out in the global peptide industry with reliable quality, stable supply and cost-effective solutions, serving global clients engaged in scientific research, biotech, healthcare and cosmetic fields.

Quality is our core competitive advantage. We strictly follow standardized production and quality control systems, with all peptide products including Vesugen polypeptide tested by high-precision HPLC to ensure a purity of 98%-99%. Equipped with independent sterile laboratories and advanced testing equipment, we conduct full-process monitoring from raw material screening, synthesis, purification to lyophilization. Every batch of products comes with complete test reports, guaranteeing high stability, high activity and zero impurities, fully meeting international research and commercial application standards.

We own standardized automated production lines to support flexible and scalable production. We efficiently handle orders ranging from small-batch trial samples to large-scale bulk customization, realizing stable mass production while shortening delivery cycles. Different from middlemen and distributors, we have full control over production links, effectively cutting intermediate costs and offering factory-direct competitive prices without compromising product quality.

Supported by a professional technical team with years of peptide synthesis experience, we master mature lyophilization and peptide modification technologies. Besides conventional peptide products, we provide one-stop customized services including exclusive sequence synthesis, formula optimization and professional reconstitution guidance. We offer accurate technical instructions for product dilution, concentration calculation and storage, solving all technical problems for clients.

We adhere to strict warehouse and logistics management. Lyophilized peptides are stored in low-temperature and light-proof environments to ensure long-term activity retention. We provide secure vacuum packaging and global fast delivery, along with thoughtful after-sales support. Choosing us means you gain high-quality products, professional technology, stable supply and cost-effective prices all in one reliable partner.

.
ECHEMI Editorial Reference

GS-441524 is a nucleoside analogue that terminates the RNA chain of viral RNA-dependent RNA polymerase. GS-441524 was developed by Gilead Sciences, Inc as part of their research into human RNA virus disease such as Ebola. GS-441524 is a small molecule that exhibits potent antiviral activity against a number of RNA viruses, including the zoonotic severe acute respiratory syndrome (SARS) coronavirus ( Cho et al., 2012).
GS-441524 is a C-nucleoside analog that is (2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile substituted by a 4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl group at position 2. It is the active metabolite of remdesivir and exhibits a broad range of inhibitory activity against various RNA viruses including HCV, parainfluenza and SARS-CoV. It has a role as a drug metabolite, an antiviral agent and an anticoronaviral agent. It is a pyrrolotriazine, a nitrile, a C-nucleoside and an aromatic amine.|GS-441524 is an adenosine nucleotide analog antiviral, similar to [remdesivir]. This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent. GS-441524 continues to be studied in the treatment of Feline Infectious Peritonitis Virus, a coronavirus that only infects cats.
Certificates
- TDS
Basic Info

Product Name:
GS-441524

Other Name:
(2R,3R,4S,5R)-2-(4-Aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydro-2-furancarbonitrile;GS-441524;GS441524;(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile;GS-441524 solution;EVO984;EVO 984;EVO-984;GS 441524

CAS No.:
1191237-69-0

Molecular Formula:
C12H13N5O4

InChIKeys:
BRDWIEOJOWJCLU-LTGWCKQJSA-N

Molecular Weight:
291.26

Exact Mass:
291.096754

UNII:
1BQK176DT6

Categories:
Bulk Drug Intermediates

Characteristics

PSA:
150

XLogP3:
-1.27552

Density:
1.84±0.1 g/cm3(Predicted)

See More GS-441524 Properties 
Seller Information

Business Type:
Trader

Main Products:
Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

Location:
Hefei, Provincia de Anhui

Year of Establishment:
2026

Inquiry History

42 Inquiries

Country	Product	Purchase Quantity	Date Posted
Turkey	GS441524 powder CAS 1191237-69-0 Remdesivir GS-5734 Alprostadil pge	1 PCS	Jan 6, 2026
Bulgaria	Lowest price in the whole network 1191237-69-0 GS-441524	100 BOU	Nov 8, 2023
United States	GS441524 CAS 1191237-69-0 Cat Fip GS441 liquid 20mg 30mg 6ml 8ml 10ml	4 MT	Oct 18, 2023
China	GS 441524	1 KG	Dec 5, 2023
United States	GS-441524	100 MT	Jul 9, 2026
Poland	GS441524 powder	200 G	Mar 11, 2026
United States	gs441524	100	Feb 10, 2026
South Korea	GS-441524 20mg tablets	3 PCS	Feb 5, 2026
Canada	Alprostadil	10 PCS	Nov 25, 2025
Portugal	GS-441524	10 G	Nov 17, 2025
Germany	Gs 441524 99.9% purity white powder	20 G	Mar 30, 2025
Portugal	GS-441524	16 MG	Jan 8, 2025
Pakistan	GS-441524	10 G	Sep 13, 2024
United States	Gs441524	100 MT	Apr 3, 2024
Turkey	GS-441524	100 G	Feb 16, 2024
Pakistan	GS-441524	21 MT	Feb 11, 2024
United States	gs441524	250 L	Dec 28, 2023
United States	GS 441524	10 L	Dec 21, 2023
Pakistan	Gs-441524	10 KG	Dec 5, 2023
United States	GS-441524 Powder 98%	1 KG	Nov 18, 2023

Go to Page

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
GS-441524	Pharma Grade/99	$28/KG EXW	DAHAI BIOCHEM LTD	Inquiry
Fip Cat Gs-441524 Fipv CAS 1191237-69-0 Treatment China Factory Supply	Top Grade/99	$2.5/UNIT FOB	Hebei Tengchu trading Co., LTD	Inquiry
GS-441524 CAS 1191237-69-0 Broad-Spectrum Antiviral Nucleoside for FIPV and Coronavirus hfd	Reagent Grade/99	$100-130/G FOB	Jinan topfull chemical co.,ltd	Inquiry
Top Quality 99% Peptides Lyophilized Powder Alprostadil lose Weight	Pharmaceutical Grade/99	$25-30/UNIT FOB	Silk Road Trading Co.,Ltd	Inquiry
GS-441524 high quality supply	/	$1/MT EXW	Jinan Million Pharmaceutical Co., Ltd	Inquiry

Alprostadil 99% Pharmaceutical Grade High Purity Factory Supply Hot selling

Product Description

Seller Information

Inquiry History

1. Product Overview

2. Basic Specifications

3. Mechanism of Action

4. Core Benefits & Applications

5. Advantages of 99% Pharmaceutical-Grade Alprostadil

6. Safety & Usage Features

More Choices Find All Products for Sale 

Related Searches

More from this Seller

Items	Specifications