1.Basic Introduction

  MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino-acid mitochondrial-derived bioactive peptide encoded by mitochondrial 12S rRNA gene, a classic mitokine widely used in metabolic and aging-related preclinical research.

2.Core Functions & Mechanisms

• Regulate Energy Metabolism & Improve Insulin Sensitivity

  Activates the core AMPK signaling pathway to boost cellular glucose uptake and fatty acid oxidation, significantly improves insulin resistance, lowers blood glucose and visceral fat accumulation. It is known as an exercise mimetic peptide that simulates the metabolic benefits of physical exercise.

  Mitochondrial Protection & Antioxidation

  Promotes mitochondrial biogenesis, repairs damaged mitochondria, eliminates intracellular reactive oxygen species (ROS) via activating the Nrf2 antioxidant pathway, alleviates oxidative stress-induced cell aging and tissue damage.

  Anti-Inflammatory Effect

  Inhibits the release of pro-inflammatory cytokines (TNF-α, IL-6), relieves chronic low-grade inflammation caused by obesity and aging, improves systemic metabolic inflammatory status.

  Skeletal Muscle Protection & Anti-Sarcopenia

  Enhances muscle energy supply, inhibits skeletal muscle protein decomposition, improves exercise endurance, delays age-induced muscle atrophy and muscle function decline.

  Bone & Neuroprotective Effects

  Promotes osteoblast proliferation to increase bone density for osteoporosis research; crosses the blood-brain barrier to reduce neuronal oxidative injury, exerts protective effects on neurodegenerative lesions.

  
  

  
  

  3.Main Research Directions

  1. Metabolic Disease Research

     
     

     Preclinical study on obesity, type 2 diabetes, non-alcoholic fatty liver disease, insulin resistance and metabolic syndrome; comparative pharmacology research with GLP-1 peptides.
  2. Mitochondrial Physiology & Aging Research

     
     

     Mechanism exploration of mitochondrial quality control, cellular senescence delay, age-related metabolic decline and longevity intervention research.
  3. Sarcopenia & Sports Medicine Research

     
     

     Study on skeletal muscle energy metabolism, exercise endurance improvement, prevention and intervention of age-related muscle atrophy.
  4. Neurodegenerative & Bone Disease Research

     
     

     Intervention mechanism for Alzheimer’s disease, cerebral ischemic injury, senile osteoporosis and postmenopausal bone loss.
  5. Chronic Inflammation & Organ Injury Research

     
     

     Research on chronic metabolic inflammation, cardiovascular endothelial injury, liver and kidney oxidative damage protection.
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     Company Profile: Tianjin Huifeng Technology Co., Ltd. is a company specializing in the production of various peptide products and chemical raw materials. We have a professional R&D team and an efficient and reliable logistics team to ensure that you can receive high-quality products safely and on time. Our customers are located in the United States, Europe, Japan, South Korea, India, and other regions. Most of our main products are in stock and can be shipped immediately. Please inform us of your specific quantity requirements, and we will provide you with the most competitive prices. Welcome to contact us at any time for more information.
We offer a wide range of peptide products, which are widely used in life science research, drug development, cosmetics, anti-aging medicine, and functional health supplements. We guarantee excellent product quality and competitive prices. Customers who have ordered our peptide products have always given high evaluations. We sincerely welcome reliable buyers from all over the world to contact us and negotiate business cooperation for peptide products. 1. Outstanding Product Quality
Product quality is the foundation of our business. Our peptide compounds are synthesized using the solid-phase peptide synthesis method (SPPS), purified by high-performance liquid chromatography (HPLC), and verified by mass spectrometry (MS).
Each batch of products comes with an analysis certificate (COA), which contains key data: ••• Purity (HPLC) • Molecular weight (MS) • • • Moisture content • • • Residual solvents • • Microbial limits (if applicable).
For customers with stricter regulatory requirements, we can also provide third-party testing reports, endotoxin (LAL) data, and stability study documents. 2. Customized Services and R&D Support
We provide flexible customized synthesis services and support from an experienced R&D team. Whether you need a new peptide sequence, cosmetic-grade purity, or modified molecules (such as PEGylation or acetylation), we can deliver high-quality products on time. Our services include:
•• Custom peptide synthesis (milligram to kilogram level)
••• Peptide modification and labeling
•• Small molecule synthesis
• Project-based R&D and large-scale production
We work closely with our clients to ensure technical feasibility, rapid delivery, and cost control throughout the entire development cycle. 3. Diverse product portfolio
We offer a wide range of products that are continuously expanding:
••• Peptides: GLP-1 analogues (such as sitagliptin, tazapetide, retactide, etc.), cosmetic-grade peptides (such as acetyl hexapeptide-8, Matrixyl, etc.), anti-aging peptides, and research-grade peptides.
•• Small molecule compounds: Cognitive enhancers, NAD+ precursors/promoters (such as NMN, NR, NADH) and intermediates.
• Biochemical products: Amino acid derivatives, enzyme cofactors, and custom reagents.
To meet the constantly changing market demands, we regularly introduce new products. At the same time, we also provide batch pre-order services for customers with continuous or seasonal demands.

(FAQ)
Q1: Are you a supplier or a manufacturer?
A: We are both a supplier and a manufacturer. Q2: How do you make the delivery?
A: We have established stable cooperative relationships with DHL, TNT, UPS, FedEx, EMS, China Post Air Express, etc. For container transportation, we can arrange for sea shipping; you can also choose your own freight forwarder.
Q3: What payment methods do you accept?
A: We accept Bitcoin and USDT.
Q4: How about the after-sales service?
A: We offer high-quality products and guarantee 100% safe delivery.
Q5: How do you ensure product quality?
A: We will send you the analysis report (COA) of the sample to confirm the quality.
Q6: How can we verify the quality of the products before placing an order?
A: For some products, free samples are available. You only need to bear the shipping cost or arrange for a courier to pick them up. You can also provide the product specifications and requirements, and we will produce them accordingly.
Q7: Are there any discount offers?
A: Yes, the larger the order quantity, the more favorable the price will be.

NAME: LILY
WHATSAPP:+8619948099954
+852 9842 2806
EMAIL:sales02@yw-jl.cn
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Manufacturer advantages

We support payment methods including Alipay, bank cards and USDT

We offer global shipping via EMS and FedEx with full tracking and secure delivery to all regions worldwide.