Embelin
550-24-3
Industrial Grade
98%
guangzhou
20mg
2026-07-27
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceEmbelin is a cell-permeable benzoquinone compound that exhibits antitumor properties. Specifically antagonizes XIAP-mediated inhibition of caspase-9 activation by directly targeting the Smac and caspase-9 binding domain BIR3 (IC50 = 4.1 uM in a competitive binding assay with Smac peptide).IC50 value: 4.1 uM [1]Target: XIAPin vitro: Embelin induced activation of caspase-9 and embelin-induced apoptosis was prevented by caspase inhibitors [2]. Treatment with subtoxic doses of Embelin broadl
Embelin is a member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease. It has a role as a hepatitis C protease inhibitor, an antimicrobial agent, an antineoplastic agent and a plant metabolite.Basic Info-
Product Name:
Embelin
Other Name:2,5-Cyclohexadiene-1,4-dione,2,5-dihydroxy-3-undecyl-;p-Benzoquinone,2,5-dihydroxy-3-undecyl-;Embelin;2,5-Dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4-dione;Embelic acid;Emberine;NSC 91874;2,5-Dihydroxy-3-undecyl-1,4-benzoquinone;2,5-Dihydroxy-3-undecylcyclohexa-2,5-dien-1,4-dione
CAS No.:550-24-3
Molecular Formula:C17H26O4
InChIKeys:InChIKey=IRSFLDGTOHBADP-UHFFFAOYSA-N
Molecular Weight:294.39
Exact Mass:294.39
EC Number:208-979-8
UNII:SHC6U8F5ER
NSC Number:91874
DSSTox ID:DTXSID80203537
HScode:2914690090
Categories:
Characteristics-
PSA:
74.6
XLogP3:5.4
Appearance:solid
Density:0.27 g/cm3
Melting Point:142.5 °C
Boiling Point:431.9°C at 760 mmHg
Flash Point:229.1±25.2 °C
Refractive Index:1.538
Water Solubility:DMSO: >10 mg/mL
Storage Conditions:Store at +4°C
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5
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Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
51-100
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Year of Establishment:
2019
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Country Product Purchase Quantity Date Posted Post an enquiry for this product