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Physcion 1-glucoside

Unit Price:

$8000-9000/G EXW

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CAS No.:

26296-54-8

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Packaging:

10mg

Price valid (until):

2026-07-22

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
Seller Information

Description

Physcion 1-glucoside (also known as physcion-1-O-β-D-glucoside or physcion-1-O-β-D-monoglucoside) is a natural anthraquinone glycoside. It is found in traditional medicinal herbs such as Polygonum multiflorum (He Shou Wu), Rumex japonicus (Japanese Dock), and Rheum officinale (Chinese Rhubarb).

Pharmacologically, it acts as a tumor cell growth inhibitor, anti-inflammatory agent, and agricultural fungicide.

The primary biological functions and mechanisms of Physcion 1-glucoside include:

1. Tumor Cell Growth Inhibition (Anticancer)

Physcion 1-glucoside serves as a noteworthy anti-proliferative agent against several cancer cell lines:

Induction of Apoptosis: It actively halts the survival pathways of malignant cells, triggering programmed cell death (apoptosis).
Leukemia Suppression: Recent oncological profiling identifies it as an effective natural compound against Acute Lymphoblastic Leukemia (ALL), where it targets uncontrolled lymphocyte accumulation with low relative systemic toxicity.
Broad In Vitro Efficacy: It suppresses rapid cell division across multiple target tumor types, working similarly to its aglycone base, physcion.
2. Crop Defense & Antifungal Activit

In agricultural biotechnology, it functions as a highly effective, eco-friendly biopesticide:
- Powdery Mildew Control: It serves as an active compound for controlling Blumeria graminis, the destructive fungus responsible for wheat powdery mildew.
- Infection Interruption: By penetrating the fungal wall, it disrupts the infection process and prevents agricultural spore propagation without harming the host crop.
3. Anti-Inflammatory & Metabolic Support
- Cytokine Suppression: Like many anthraquinones extracted from Rhubarb, it helps downregulate inflammatory signaling networks.
- Enzyme Regulation: It acts on the body's natural antioxidant defense mechanisms, lowering oxidative tissue damage caused by chronic metabolic stress.
4. Pharmacokinetic Carrier (The Glucoside Role)

From a pharmacognosy perspective, attaching the glucose molecule to the 1-O position alters how the compound behaves in the body:
- Enhanced Solubility: The sugar moiety (glycone) drastically increases the compound's water solubility compared to raw physcion.
- Targeted Delivery: The glucose ring serves as a carrier, allowing the inactive glycoside to pass smoothly through the digestive tract until it is hydrolyzed by gut microbiota, releasing the highly active aglycone at the site of action.

Basic Info

Product Name:

Physcion 1-O-β-D-glucoside

Other Name:

9,10-Anthracenedione,1-(β-D-glucopyranosyloxy)-8-hydroxy-6-methoxy-3-methyl-;Physcionin;1-(β-D-Glucopyranosyloxy)-8-hydroxy-6-methoxy-3-methyl-9,10-anthracenedione;Physcion 1-β-D-glucopyranoside;3-Methyl-6-methoxy-1,8-dihydroxyanthraquinone 1-glucoside;Physcion 1-O-β-D-glucoside;Physcion 1-O-β-D-glucopyranoside;37310-93-3;72108-63-5

CAS No.:

26296-54-8

Molecular Formula:

C22H22O10

InChIKeys:

InChIKey=WLXGUTUUWXVZNM-DQMLXFRHSA-N

Molecular Weight:

446.40408

Exact Mass:

446.40

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

162.98000

XLogP3:

1.72

Density:

1.567±0.06 g/cm3 (20 ºC 760 Torr)

Melting Point:

235 °C

Boiling Point:

796.3±60.0 °C at 760 mmHg

Flash Point:

280.3±26.4 °C

Refractive Index:

1.681

See More Physcion 1-O-β-D-glucoside Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Physcion 1-O-β-D-glucoside Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

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