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Cucurbitacin IIb

Unit Price:

$150000-180000/G FOB

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CAS No.:

50298-90-3

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Packaging:

20mg

Price valid (until):

2026-07-22

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
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Description
Cucurbitacin IIb (also known as hemslecin B) is an active triterpenoid compound found in Hemsleya amabilis, a plant traditionally used in Eastern medicine to treat infections. It functions primarily as an anti-inflammatory, antiviral, and apoptosis-inducing agent.

Primary functions include:

Anti-inflammatory Properties: It treats intestinal and respiratory issues (like bacillary dysentery and enteritis) by inhibiting inflammatory pathways such as NF-κB and blocking the production of pro-inflammatory cytokines like IL-6, IL-1β, and TNF-α.

Anticancer & Tumor Suppression: It restricts cancer cell proliferation (e.g., in cervical and lung cancers) by inducing cell cycle arrest and apoptosis. It acts as a potential EGFR tyrosine kinase inhibitor (TKI) and suppresses pathways like JAK/STAT3.

Gut Microbiota Modulation: It has been shown to alleviate gut inflammation (colitis) by regulating gut microbial composition and metabolites.

Immunomodulation: It suppresses the adaptive immune response by inhibiting the proliferation and activation of T-lymphocytes.
Basic Info

Product Name:
Dihydrocucurbitacin F

Other Name:
19-Norlanost-5-ene-11,22-dione,2,3,16,20,25-pentahydroxy-9-methyl-,(2β,3α,9β,10α,16α)-;(2β,3α,9β,10α,16α)-2,3,16,20,25-Pentahydroxy-9-methyl-19-norlanost-5-ene-11,22-dione;23,24-Dihydrocucurbitacin F;Cucurbitacin IIb;Dihydrocucurbitacin F;Hemslecin B;129357-89-7;881024-53-9

CAS No.:
50298-90-3

Molecular Formula:
C30H48O7

InChIKeys:
InChIKey=VVBWBGOEAVGFTN-LPQIEKFGSA-N

Molecular Weight:
520.69800

Exact Mass:
520.70

Categories:
Bulk Drug Intermediates

Characteristics

PSA:
135.29000

XLogP3:
2.94430

Density:
1.22g/cm3

Melting Point:
155-156 °C

Boiling Point:
668.4ºC at 760 mmHg

Flash Point:
372ºC

Refractive Index:
1.576

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Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

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Cucurbitacin IIb

Product Description

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