Trifarotene RC10393
2 Inquiries
895542-09-3
Pharmaceutical Grade
99%
Royalchem
25kg/drum
Yes
2030-01-01
Pharmaceutical intermediates
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceTrifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019. Retinoids are a class of medications structurally and functionally analogous to [vitamin A], though later generation retinoids such as trifarotene and [adapalene] bear little structural resemblance to vitamin A and are analogous only in function. Trifarotene is considered the first of the "fourth-generation" retinoids due to its uniquely selective activity - this selectivity appears to confer improved efficacy and reduced side effects as compared to older, less selective retinoids.|Trifarotene is a selective retinoic acid receptor gamma (RAR gamma) agonist that can be used in the treatment of acne vulgaris. Upon topical application, trifarotene selectively binds to the RAR gamma receptor, thereby altering the expression of certain genes that are involved in inflammation and cellular differentiation.Basic Info
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Product Name:
3′′-(1,1-Dimethylethyl)-4′-(2-hydroxyethoxy)-4′′-(1-pyrrolidinyl)[1,1′:3′,1′′-terphenyl]-4-carboxylic acid
Other Name:[1,1′:3′,1′′-Terphenyl]-4-carboxylic acid,3′′-(1,1-dimethylethyl)-4′-(2-hydroxyethoxy)-4′′-(1-pyrrolidinyl)-;3′′-(1,1-Dimethylethyl)-4′-(2-hydroxyethoxy)-4′′-(1-pyrrolidinyl)[1,1′:3′,1′′-terphenyl]-4-carboxylic acid;3′′-tert-Butyl-4′-(2-hydroxyethoxy)-4′′-(pyrrolidin-1-yl)[1,1′:3′,1′′]terphenyl-4-carboxylic acid;Trifarotene;CD 5789;Aklief
CAS No.:895542-09-3
Molecular Formula:C29H33NO4
InChIKeys:InChIKey=MFBCDACCJCDGBA-UHFFFAOYSA-N
Molecular Weight:459.6
Exact Mass:459.58
UNII:0J8RN2W0HK
DSSTox ID:DTXSID30237781
NCI Thesaurus Code:C118577
ATC Code:D - Dermatologicals
Categories:
Characteristics-
Melting Point:
245C
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
Pakistan
TRIFAROTENE
50 MG Mar 13, 2025
Pakistan
TRIFAROTENE
1 KG Feb 25, 2025 Post an enquiry for this product
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