Scandium(III) Trifluoromethanesulfonate 98%-99.995% Purity Lewis Acid Catalyst CAS 144026-79-9 for Organic Synthesis

• Water-stable Lewis acid: Unlike traditional moisture-sensitive Lewis acids, Sc(OTf)₃ is stable in water and can be used in aqueous media, enabling environmentally friendly reaction conditions
• High catalytic activity: Effective at very low catalyst loadings (typically 1-10 mol%, sometimes as low as 0.1 mol%)
• Excellent recoverability: Can be recovered from reaction mixtures and reused multiple times without significant loss of catalytic activity
• Broad substrate scope: Catalyzes a wide range of organic transformations with high chemo-, regio-, and stereoselectivity
• Mild reaction conditions: Often proceeds at room temperature or moderate heating, reducing energy consumption
• Low toxicity: Compared to many traditional Lewis acids, scandium triflate has relatively low toxicity
• Multiple purity grades: Available from 98% technical grade to 99.995% trace metals grade for electronic and semiconductor applications

1. 1.Diels-Alder & cycloaddition reactions: Endo-selective cycloadditions, including asymmetric variants with chiral ligands, in aqueous media
2. 2.Friedel-Crafts acylations and alkylations: Aromatic substitution reactions with high para-selectivity, avoiding the need for stoichiometric Lewis acids
3. 3.Mukaiyama aldol reactions: Highly stereoselective carbon-carbon bond formation with silyl enol ethers
4. 4.Glycosylation reactions: Activation of glycosyl donors for the synthesis of oligosaccharides and glycoconjugates
5. 5.Polymerization reactions: Stereocontrolled polymerization of acrylates and other vinyl monomers
6. 6.Allylation and propargylation reactions: Addition of allyl and propargyl groups to carbonyl compounds and imines
7. 7.Michael additions and conjugate reactions: 1,4-addition of various nucleophiles to α,β-unsaturated carbonyl compounds
8. 8.Ring-opening polymerization: Catalysis of lactide and other cyclic monomer polymerizations
9. 9.Nucleophilic substitution reactions: Activation of alcohols and other leaving groups
10. 10.Multicomponent reactions: Catalysis of Ugi, Strecker, and other MCRs for efficient compound library synthesis

• 98% Technical grade - for bulk industrial applications
• 99% Reagent grade - for general organic synthesis
• 99.9% High purity grade - for fine chemical synthesis
• 99.99% Ultra-high purity grade - for electronic and advanced materials
• 99.995% Trace metals grade - for semiconductor and specialty applications

• Packaging options: 1g, 5g, 25g, 100g, 500g, 1kg bottles; custom packaging available
• Storage conditions: Store in tightly sealed containers in a cool, dry place, protected from moisture
• Handling precautions: Hygroscopic - handle under inert atmosphere for best results
• Shelf life: 24 months under proper storage conditions
• Shipping: Can be shipped as non-hazardous chemical under standard transport conditions

Spec Sheet