raw material Calcium Glycerophosphate

Calcium Glycerophosphate More Info

Product Overview

Calcium Glycerophosphate is a calcium salt of glycerophosphoric acid that appears as a white, fine, slightly hygroscopic powder. It is a versatile compound with a range of potential benefits, from neutralizing stomach acid to supporting bone health. The commercial product is a mixture of calcium beta-, and D-, and L-alpha-glycerophosphate.

Key Specifications

Chemical Formula: C3H7CaO6P

Molecular Weight: 210.14

CAS Number: 27214-00-2

Appearance: White to almost white powder

Solubility: Soluble in water (20g/L at 25°C), slightly soluble in DMSO

Calcium Content: 18.6%-19.4%

Primary Applications

1. Food & Nutrition Supplement

Calcium glycerophosphate is considered a Generally Recognized As Safe (GRAS) food ingredient by the FDA as a nutrient supplement (source of calcium or phosphorus). It can be used in food products such as:

Gelatins and puddings

Fillings

Dietary supplements

2. Dental & Oral Care Products

It is widely used in dental or oral hygiene products due to its cariostatic effects. Key functions include:

Antiplaque: Helps prevent plaque formation

Remineralization: Elevates plaque calcium and phosphate levels

pH Buffering: Promotes plaque-pH buffering

Fluoride Enhancement: Optimizes the action of fluorides

Clinical trials have shown that the combination of Calcium Glycerophosphate with sodium monofluorophosphate (SMFP) in toothpaste formulations is more effective than SMFP alone in reducing caries .

3. Dietary Supplement

It is a high bioavailability calcium supplement that provides phosphorus, contributing to dental health and bone calcification. Common supplement brands containing Calcium Glycerophosphate include Prelief and Desert Harvest.

Recommended dosage: Typically 230mg daily

Usage suggestion: Take with food to increase pH and reduce acidity

4. Acid Neutralization

Calcium glycerophosphate serves as a neutralizing agent for stomach acid and can help reduce discomfort caused by acidic foods. It has been studied for its potential benefits in managing interstitial cystitis, a condition associated with chronic inflammation and frequent urination.

Safety & Regulatory Status

FDA GRAS Status: Regarded as safe for food use

Pharmacopoeia Listed: Included in the United States Pharmacopeia and British Pharmacopoeia

Generally Safe: When used as directed, no significant adverse effects have been reported

Storage & Handling

Storage Temperature: Should be stored at -20°C

Stock Solutions: Can be stored below -20°C for several months

Note: It is slightly hygroscopic, so proper packaging is recommended