99% High Purity Lyophilized Synthetic Peptide Powder CAS 2381089-83-2 Biomedical Lab Research

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Retatrutide, LY3437943

CAS#: 2381089-83-2

Molecular Formula: C221H342N46O68

Molecular Weight: 4731.33

Appearance: White Powder

Purity (HPLC): ≥99.0%

Single Impurity (HPLC): ≤1.0%

Sodium Content (HPLC): 5.0%-12.0%

Moisture Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Storage: Store at 2-8 degrees Celsius in a dry and cool place.

Packaging: 1g-1kg, plastic bottle

Retatrutide acetate (LY3437943) is a triple agonist peptide targeting the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

The inhibitory EC50 values of retatrutide acetate against human GCGR, GIPR and GLP-1R are 5.79 nM, 0.0643 nM and 0.775 nM respectively. It also exhibits activity against mouse GCGR, GIPR and GLP-1R, with EC50 values of 2.32 nM, 0.191 nM and 0.794 nM respectively.

In vivo, Retatrutide acetate (LY3437943) binds to GCGR and exerts effects through GIP or GLP-1 receptors to improve glucose tolerance in the intraperitoneal glucose tolerance test (ipGTT). By activating the glucagon receptor, retatrutide acetate can significantly reduce body weight and increase energy expenditure. Retatrutide acetate can be applied in research related to obesity.

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Company Profile: Tianjin Huifeng Technology Co., Ltd. is a company specializing in the production of various peptide products and chemical raw materials. We have a professional R&D team and an efficient and reliable logistics team to ensure that you can receive high-quality products safely and on time. Our customers are located in the United States, Europe, Japan, South Korea, India, and other regions. Most of our main products are in stock and can be shipped immediately. Please inform us of your specific quantity requirements, and we will provide you with the most competitive prices. Welcome to contact us at any time for more information.
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