Product Basic Profile
Lys-Pro-Val Tripeptide, abbreviated as KPV, is fully synthetic short polypeptide composed of three amino acid residues: Lysine, Proline and Valine. The whole production adopts automatic solid-phase peptide synthesis equipment for peptide chain assembly, followed by multi-step gradient elution HPLC purification to remove truncated peptide fragments and synthesis by-products. The finished raw material is white loose lyophilized powder with stable chemical structure, low endotoxin residue and excellent water solubility. It can be fully dissolved in deionized water and pH7.2 PBS buffer to form transparent homogeneous liquid samples for isolated cell incubation and biomolecular binding tests in laboratory environment.
This product is exclusively defined as special raw material for in vitro isolated lab research only. All human-related application scenarios are strictly prohibited, including oral intake, subcutaneous injection, external skin coating, clinical sample preparation, cosmetic raw material blending and other human-oriented usage modes.
Full Quality Control Index System
Full Product Name: Synthetic Lys-Pro-Val Tripeptide (KPV) CAS Registration Number: 64083-48-3 Physical Appearance: White loose lyophilized powder, no visible foreign impurity particles, no caking or moisture absorption deliquescence HPLC Purity: ≥98.0%, single impurity peptide ≤1.0%, total impurity peptides ≤2.0% Amino Acid Sequence: Lys-Pro-Val Molecular Weight: 329.4 Da Water Content: ≤5.0% Endotoxin Residue: ＜1 EU/mg Solubility: Completely soluble in ultrapure water and pH7.2 PBS aqueous solution Standard Storage Condition: Sealed, light-shielded, stored at -20℃, valid shelf life 24 months All testing items follow unified industry standards for lab polypeptide reagents. Each production batch is equipped with independent HPLC chromatogram and ESI-MS mass spectrum identification report to verify molecular weight and purity data batch by batch, ensuring stable and consistent performan
Compliant Allowed In Vitro Laboratory Research Directions
Immune cell isolated culture research: Build monocyte and macrophage isolated culture model, study the regulatory effect of KPV tripeptide on cellular inflammatory factor secretion and cell chemotaxis behavior. Mucosa cell basic mechanism experiment: Complete co-incubation of intestinal epithelial cell strains, analyze the mediating effect of KPV on mucosal cell barrier related signal pathways. Biomolecular interaction basic academic research: Carry out co-incubation test of KPV tripeptide with nucleic acid, protein and lipid biomolecules, detect molecular binding affinity to provide complete experimental data support for biochemistry academic papers. In vitro cell inflammatory injury model construction: Establish LPS-induced cell inflammatory damage model, observe the protective effect of KPV tripeptide on damaged isolated cells and explore downstream signal pathway molecular mechanism. Novel small-molecule regulatory peptide template pre-screening: Serve as standard reference tripeptide for in vitro preliminary screening of new regulatory peptide molecular templates, only limited to isolated strain and cell level testing, not used for pharmaceutical formulation preparation and clinical drug development.
Standard Storage & Operation Operating Guidelines
Long-term storage operation: Tightly seal glass vials or aluminum foil bags, store at constant temperature of -20℃ away from light and moisture, minimize repeated freeze-thaw cycles to prevent peptide chain hydrolysis and degradation. Temporary storage after opening: Keep the container tightly sealed and store under 2–8℃ environment, finish all experimental usage within 30 days after opening to avoid moisture absorption and mixed impurity pollution of samples. Standard dissolution operation rule: Prepare fresh peptide aqueous solution with sterile ultrapure water or pH7.2 PBS buffer before each experiment, discard residual diluted liquid after single use, long-term storage of diluted peptide solution is strictly prohibited. Transportation environment requirement: Avoid direct sunlight and long-time exposure to high temperature environment during whole cold chain transportation process.
