AR100-High purity, large quantity, discounted price. Factory direct sales.

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Principle of Basic Function
AR50 is high-purity  (5-aminoimidazole-4-methylcarbamoyl riboside), with the core target being AMPK (adenosine monophosphate-activated protein kinase), and is known as the overall switch of cellular metabolism; it can simulate the low-energy state of cells after exercise, continuously activate the AMPK pathway, regulate the entire metabolic chain of sugar, fat, and mitochondria, and is only used as a laboratory research reagent, without compliant oral or topical finished products.
1. Effects on Cellular Energy and Mitochondrial Enhancement
Promote mitochondrial proliferation and activity enhancement
Upregulate genes related to mitochondrial synthesis, increase the number of mitochondria within cells; improve the efficiency of mitochondrial oxidative energy supply, increase the basic output of ATP, alleviate cellular hypoxia and fatigue states, applicable for in vitro research on the energy mechanism of muscles, cardiac muscle, and brain cells.
Optimize energy supply in low-oxygen environments
Maintain stable energy metabolism under hypoxic conditions, reduce the inhibition of cell energy production caused by hypoxia, used in cell model experiments related to endurance and ischemic injury.
Reduce the accumulation of energy metabolism waste
Accelerate the decomposition of lactic acid and metabolic by-products, reduce the accumulation of cellular metabolic toxins, alleviate cellular fatigue and damage.
2. Regulation of Fat Metabolism (In vitro Fat Metabolism Model)
Accelerate fatty acid oxidation and decomposition
Activate the lipolysis pathway, convert stored fat into energy , improve the fat utilization rate of cells; reduce the accumulation of triglycerides in cells, used for research on the mechanism of fat loss and metabolic syndrome.
Inhibit fat cell differentiation and accumulation
In vitro experiments on fat precursor cells, weaken the signals of adipogenesis, reduce the generation of new fat cells, and reduce the tendency of lipid accumulation.
3. Regulation of Glucose Metabolism and Insulin Sensitivity
Enhance the ability of cells to take up glucose
Promote the expression of glucose transport proteins on the cell membrane without relying on insulin, enhance the cell's absorption and utilization of sugar, stabilize the intracellular glucose metabolism level.
Improve the state of insulin resistance
In resistance cell models induced by high sugar and high fat, restore the sensitivity of the insulin signaling pathway, used for pharmacological screening of 2-type sugar metabolism disorders.
4. Exercise Endurance and Muscle Cell Repair (Isolated Muscle Tissue)
Enhance the endurance reserve of muscle cells
Continuous activation of AMPK prolongs the duration of high-intensity energy supply of muscle cells, delays the appearance of fatigue signals, simulating the effect of long-term aerobic training on cell endurance improvement.
Reduce oxidative damage of muscle cells after exercise
Reduce reactive oxygen species produced by intense metabolism, reduce oxidative damage to muscle cell membranes and proteins; accelerate the basic repair process of damaged muscle cells, shorten the recovery period of cells.
Maintain the integrity of muscle fibers
Inhibit the excessive breakdown pathway, reduce the loss of muscle protein under high-intensity metabolism, protect the stability of muscle cell structure.
5. Antioxidant, Systemic Anti-inflammatory Cell Effects
Broad-spectrum clearance of cellular free radicals
Upregulate the expression of endogenous antioxidant enzymes, neutralize oxidative stress reactive oxygen species, reduce DNA and cell membrane oxidative damage, delay cell aging and apoptosis.
Inhibit chronic low-grade inflammatory factors
Downregulate aging and metabolism-related inflammatory mediators such as TNF-α and IL-6, alleviate continuous mild inflammation in organs and muscles, used for research on metabolic inflammation and vascular damage.
6. Cardiovascular Cell Protection (Isolated Cardiac Muscle, Vascular Endothelium)
Protect against myocardial ischemic injury
In ischemia-reperfusion cell models, reduce the proportion of myocardial cell apoptosis, stabilize myocardial energy supply, reduce myocardial cell necrosis caused by hypoxia.
Maintain the health of vascular endothelial cells
Reduce oxidative inflammation damage of endothelium, inhibit signals related to abnormal lipid deposition in blood vessels, assist in basic experiments on the mechanism of atherosclerosis.
7. Neurocell Maintenance (In vitro Brain Tissue Cells)
Maintain energy stability of neurons
Improve the function of mitochondria in brain cells, prevent the decline in neuronal vitality caused by energy deficiency.
Relieve oxidative apoptosis of neurons
Reduce the loss of neurons caused by oxidative stress in the brain, used for research on brain fatigue and neurodegenerative diseases mechanisms.