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Pharmaceutical Intermediate Pregabalin White Crystal CAS 148553-50-8 Lab Research Raw Material

Name: Pharmaceutical Intermediate Pregabalin White Crystal CAS 148553-50-8 Lab Research Raw Material
Brand: jianxin
SKU: pr2607132544
Price: 1 USD
Availability: InStock

274 Inquiries

Unit Price:

$1-1.3/MT FOB

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CAS No.:

148553-50-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

jianxin

Packaging:

25kg/Cardboard Drum

Price valid (until):

2030-01-01

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Shanghai Jianqi Chemical Company

Company Type:

Trader

Location:

China

Qualification:

Main Products:

chemical raw materials

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Pregabalin, CAS No.148553-50-8, chemical name (S)-3-(aminomethyl)-5-methylhexanoic acid, is a high-purity pharmaceutical grade white crystalline raw material belonging to gabapentinoid compounds. It is manufactured through mature asymmetric chiral synthesis and multi-stage recrystallization purification technology, presenting uniform white crystal particles with stable chiral configuration and low impurity content.

This product is a key biochemical research raw material and pharmaceutical intermediate, widely adopted by pharmaceutical R&D laboratories, drug synthesis factories and biochemistry research institutions worldwide. Its molecular structure is a lipophilic analog of GABA, with clear binding characteristics to voltage-gated calcium channel α2δ subunits, which makes it a core compound for neural mechanism research, drug synthetic route exploration, chiral separation experiment and pharmaceutical formulation development.

Our pregabalin crystal strictly follows pharmaceutical raw material production standards. Each batch undergoes full spectrum testing including HPLC purity, chiral excess, moisture, heavy metals, residual solvents and microbial limits, and can provide complete COA, MSDS, TDS and HPLC chromatogram documents for customs clearance and laboratory testing. The raw crystal features good water solubility and stable chemical properties under sealed low-temperature storage, compatible with various organic and aqueous solvent systems for synthetic reaction, cell incubation and analytical calibration experiments.

It is only supplied for laboratory scientific research and pharmaceutical compound development use, not for direct clinical administration or finished drug sales. We support flexible packaging from small trial foil bags to industrial 25kg cardboard drums, neutral OEM labeling and stable mass delivery to meet the sample testing and bulk production demands of pharmaceutical enterprises and research institutes.

Product Advantages

Ultra-high pharmaceutical grade purity ≥99% HPLC, high chiral ee value, single unknown impurity ≤0.1%, total impurities controlled at ultra-low level, fully matching lab research and drug synthesis raw material standards.
Uniform white crystal morphology, stable crystal form, good fluidity and solubility, fast dissolution in purified water, methanol and ethanol without turbidity or precipitation during experimental preparation.
Strict full-process quality control system. Every batch supports complete test verification including molecular weight identification, chiral analysis and residual solvent detection, full official test certificates provided upon shipment.
Stable chemical & chiral structure, not easy to racemize under specified storage environment, long shelf life up to 24 months, no activity attenuation for long-term stock.
Wide compatibility with common pharmaceutical solvents and reaction raw materials, suitable for multi-step chiral synthesis, cell mechanism study, HPLC reference calibration and impurity methodology research.
Flexible packaging & customized service: supply 1g/5g trial samples, 1kg vacuum aluminum bags and 25kg industrial drums; neutral non-logo packaging, customized labels and fast delivery for global buyers.
Factory direct supply with stable monthly output, complete export customs supporting documents, professional after-sales technical support for pharmaceutical R&D clients.

Items	Specifications
Product Name	Pregabalin
Appearance	White Crystalline Powder
Purity	≥99% HPLC

Basic Info

Product Name:

Pregabalin

Other Name:

Hexanoic acid,3-(aminomethyl)-5-methyl-,(3S)-;Hexanoic acid,3-(aminomethyl)-5-methyl-,(S)-;(3S)-3-(Aminomethyl)-5-methylhexanoic acid;PD 144723;CI 1008;Pregabalin;Lyrica;(S)-Pregabalin;(S)-(+)-3-(Aminomethyl)-5-methylhexanoic acid;(2S)-3-(Aminomethyl)-5-methylhexanoic acid;Gabanext 75;Pregalin 75;Neugaba 75;Maxgalin 75;Mahagaba-75;(S)-3-(Aminomethyl)-5-methylhexanoic acid

CAS No.:

148553-50-8

Molecular Formula:

C8H17NO2

InChIKeys:

InChIKey=AYXYPKUFHZROOJ-ZETCQYMHSA-N

Molecular Weight:

159.22600

Exact Mass:

159.23

EC Number:

604-639-1

UNII:

55JG375S6M

DEA Code Number:

2782

DSSTox ID:

DTXSID1045950

NCI Thesaurus Code:

C64625

Color/Form:

White to off-white crystalline solid

ATC Code:

N03AX16|QN03AX16|N - Nervous system

HScode:

2915900090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

63.32000

XLogP3:

1.78240

Appearance:

Solid

Density:

0.997 g/cm3

Melting Point:

195 °C (decomp) @ Solvent: Isopropanol

Boiling Point:

274ºC at 760 mmHg

Flash Point:

119.5ºC

Refractive Index:

1.464

Water Solubility:

deionized water: ≥10mg/mL

Storage Conditions:

Store at 25 deg C (77 deg F); excursions permitted to 15 to 30 deg C (59 to 86 deg F).

Vapor Pressure:

0.00153mmHg at 25°C

Specific rotation:

Specific optical rotation = +10.52 deg/D (c = 1.00 in water)

Henrys Law Constant:

Henry's Law constant = 6.89X10-11 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa1 = 4.2; pKa2 = 10.6

Experimental Properties:

The log of the partition coefficient (n-octanol/0.05M phosphate buffer) at pH 7.4 is -1.35|Hydroxyl radical reaction rate constant = 4.1X10-11 cu cm/molec-sec at 25 °C (est)

See More Pregabalin Properties 

Hazard Identification

Classification of the substance or mixture

Serious eye damage, Category 1

Reproductive toxicity, Category 2

Specific target organ toxicity â repeated exposure, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H318 Causes serious eye damage H361 Suspected of damaging fertility or the unborn child H373 May cause damage to organs through prolonged or repeated exposure
Prevention	P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P203 Obtain, read and follow all safety instructions before use. P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response	P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P318 IF exposed or concerned, get medical advice. P319 Get medical help if you feel unwell.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Pregabalin Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
chemical raw materials

Location:
Building 1, Unit 5, Room 313, Building L, No. 688 Qiushi Road, Jinshuiwei Town, Jinshan District, Shanghai

Average lead Time:
10

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2019

Inquiry History

274 Inquiries

Country	Product	Purchase Quantity	Date Posted
Oman	White Crystalline powder Pregabalin Lyrica 148553-50-8 HALAL ISO	1 KG	Jan 16, 2024
United States	Pregabalin powder CAS 148553-50-8	100 G	Aug 21, 2023
United Arab Emirates	Pregabalin CAS 148553-50-8	1 KG	Jan 20, 2024
Netherlands	Pregabalin powder CAS 148553-50-8	10 KG	Sep 27, 2023
Saudi Arabia	Pregabalin powder CAS 148553-50-8	1 KG	Aug 25, 2023
Turkey	Pregabalin powder CAS 148553-50-8	1 KG	Oct 9, 2023
United Arab Emirates	Pregabalin powder CAS 148553-50-8	1 KG	Sep 25, 2023
United States	Pregabalin powder CAS 148553-50-8	3 G	Oct 29, 2023
United States	Pregabalin powder CAS 148553-50-8	1 KG	Aug 3, 2023
Saudi Arabia	Pregabalin powder CAS 148553-50-8	3 KG	Jul 31, 2023
Saudi Arabia	CAS 148553-50-8 Lyrica Pregabalin wego	2 KG	Sep 23, 2023
Switzerland	Pregabalin Manufacturer 148553-50-8 For Antiepileptic Drugs	2000 MT	Aug 27, 2023
United States	Top Quality Pregabalin CAS 148553-50-8 in Stock 99% White powder CAS 148553-50-8 YuanLong	50 G	Sep 10, 2023
Sweden	High Purity Pregabalin CAS 148553-50-8 Crystalline powder	500 G	Feb 16, 2026
Finland	Best Price Pregabalin CAS 148553-50-8 In Stock	1 KG	Sep 24, 2023
United States	High Quality Pregabalin 99% powder 148553-50-8	222 G	Jul 4, 2024
Qatar	hot sell pregabalin lyrica pregabalin powder CAS 148553-50-8	1 MT	Nov 5, 2023
United Arab Emirates	hot sell pregabalin lyrica pregabalin powder CAS 148553-50-8	1 KG	Nov 1, 2023
Turkey	High Purity in Stock Pregabalin CAS 148553-50-8 99%	100 KG	Oct 29, 2023
Oman	hot sell pregabalin lyrica pregabalin powder CAS 148553-50-8	1 KG	Oct 4, 2023

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Pharmaceutical Intermediate Pregabalin White Crystal CAS 148553-50-8 Lab Research Raw Material

Product Description

Seller Information