Mass Spec Verified Mazdutide Long-Chain Peptide Substrate for Academic Biotech Tests

Mazdutide is a long-chain artificially synthesized oxyntomodulin analog polypeptide prepared by mature solid-phase peptide synthesis and multi-step reverse-phase chromatographic purification technology. It features a complete fixed modified amino acid sequence, stable three-dimensional molecular spatial conformation and consistent batch-to-batch component proportion.
This dual-target polypeptide acts as a core standardized experimental material widely applied in endocrinology, cell biology and molecular metabolic signal research fields. It is extensively adopted by university life science laboratories, biotechnology R&D centers and global academic research groups. Under strictly controlled sterile laboratory environments, researchers utilize Mazdutide to carry out systematic basic research including long-chain modified peptide structural characteristic identification, binding affinity analysis between polypeptide ligands and two types of cell surface target receptors (GLP-1R & GCGR), intracellular multi-level biochemical cascade reaction rules and cross-talk of dual signal transmission networks.
Full-process closed-loop quality monitoring and batch full sampling inspection are implemented throughout the whole production line. Complete traceable test documents such as COA, HPLC chromatograms and mass spectrum identity verification reports can be provided for each batch, ensuring stable molecular composition and highly repeatable experimental performance between different batches. This product is strictly limited to in vitro laboratory testing and academic research activities only.

Product Name: Mazdutide (Synonym: IBI362, LY3305677)
CAS Number: 2259884-03-0
Molecular Formula: C₂₁₀H₃₂₂N₄₆O₆₇
Molecular Weight: 4563.07 Da
Appearance: White to off-white sterile fluffy lyophilized powder
Purity: ≥99%, verified by HPLC, mass spectrometry and full peptide sequencing
Single Maximum Impurity: ≤0.5%
Endotoxin Content: ≤10 EU/mg
Solubility: Freely soluble in sterile water, PBS and standard laboratory aqueous buffer solutions
Storage Condition: Keep tightly sealed, store at -20°C; shield from strong light, humid air and repeated freeze-thaw cycles
Shelf Life: 24 months under specified storage; reconstituted solution remains stable for 3–7 days at 2–8°C
Packaging Specification: Independent sterile glass vials with blank unlabeled packaging, exclusive sealed packing for laboratory research
Application Scope: Exclusively used for laboratory scientific research, biochemical detection and all types of in vitro cell culture experiments

• Ultra-high Purity & Complete Molecular Structural Stability

  
  

  Adopting multi-stage chromatographic separation and low-temperature sterile vacuum lyophilization processes, the product overall purity reaches above 99%. HPLC, mass spectrometry and full-length peptide sequencing are adopted for full batch identity verification. Vacuum freeze-drying technology effectively locks intact peptide spatial structure and prevents molecular denaturation or fragmentation, delivering accurate, stable and reproducible experimental data for long-cycle metabolic cell research projects.
• Fast Dissolution & Simple Laboratory Operation

  
  

  The fluffy loose lyophilized powder dissolves rapidly in all conventional lab aqueous solvents without extra solubilizing additives. Operators can conveniently prepare high-concentration stock solutions and working diluents, fully matching daily operation demands of cell incubation, dual-receptor binding affinity detection and diversified in vitro biochemical analysis experiments.
• Unique Dual-Receptor Research Value

  
  

  With specially optimized long-acting modified amino acid sequence design, this polypeptide can simultaneously interact with GLP-1 and glucagon cell surface target molecules. It is the standardized experimental sample for studying synergistic binding mechanisms of dual-target peptides, comparative analysis of single-pathway and dual-pathway signal activation, and intracellular composite metabolic biochemical response rules, covering multiple cutting-edge directions of incretin peptide research.
• Comprehensive Traceable Quality Document System

  
  

  Customers can apply for a full set of supporting certification materials on demand, including Certificate of Analysis, HPLC chromatogram records, mass spectrum identification data and microbial limit test reports. All production flows follow unified manufacturing specifications for biological laboratory peptide reagents, meeting the quality access standards of research institutions in various regions worldwide.
• Excellent Long-Term Low-Temperature Storage Stability

  
  

  Equipped with light-blocking and moisture-proof fully sealed vial packaging, the product can maintain intact molecular conformation and stable biochemical properties for 24 months under -20°C storage environment. The prepared aqueous solution also keeps steady within the valid storage period, adapting to both short-term rapid detection tests and continuous long-cycle metabolic cell culture research.

• Basic research on structural characteristics and physicochemical properties of long-chain modified oxyntomodulin analog peptides
• In vitro experimental analysis of dual-target binding affinity between polypeptides and GLP-1 / glucagon cell surface receptors
• Exploration of intracellular multi-signal cascade reactions triggered by dual-ligand metabolic peptides
• Construction and optimization of in vitro hepatocyte and adipocyte cell models for metabolic research
• Comparative study on signal activation differences between single-target GLP-1 peptides and dual-target polypeptides
• Research on structure-activity relationship of long-acting fatty acid modified polypeptide compounds

Hong Kong Bosen Polypeptide R&D Co., Ltd. is a world-leading manufacturer and supplier of peptide products and pharmaceutical raw materials, specializing in the chemical industry.
Our main products include peptide products and pharmaceutical raw materials. We possess strong R&D capabilities, exquisite synthesis technologies and advanced quality control methods. We actively carry out joint ventures and cooperation with major enterprises and manufacturers, and serve society and users adhering to the concept of industrial development. We always adhere to the orientation of market demand and continuously develop new high-tech chemical products and pharmaceutical intermediates.
I am full of confidence in the quality of our products, and many overseas customers have given high praise after receiving the goods. Our products are of excellent quality, and we solemnly promise door-to-door delivery services worldwide. 4. We provide high-quality after-sales service aiming at customer satisfaction.