Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99% Purity | 5mg 10mg 15mg 20mg 30mg 40mg 50mg 60mg 100mgVials | Lyophilized Powder

  Product Detail  

Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.

In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.

Retatrutide, LY3437943

CAS#: 2381089-83-2

Molecular Formula: C221H342N46O68

Molecular Weight: 4731.33

Sequence: H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Appearance: White Powder

Purity (HPLC): ≥99.0%

Single Impurity (HPLC): ≤1.0%

Sodium Content (HPLC): 5.0%-12.0%

Moisture Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Storage: Store at 2-8 degrees Celsius in a dry and cool place.

Packaging: 1g-1kg, plastic bottle

Intended Use: For scientific research purposes

Function

1.Treatment of depression and anxiety disorders: Retatrutide has been shown to have antidepressant and anxiolytic effects in preclinical studies, suggesting that it could be a promising treatment option for individuals with these conditions.

2.Prevention of neurodegenerative diseases: Retatrutide has neuroprotective properties that may be useful in preventing or slowing the progression of neurodegenerative diseases such as Alzheimer's and Parkinson's.

3.Enhancement of cognitive function: Retatrutide has been shown to improve learning and memory in animal studies, suggesting that it could have potential as a cognitive enhancer in humans.

4.Treatment of chronic pain: Retatrutide has been shown to have analgesic effects in preclinical studies, suggesting that it could be a useful treatment option for individuals with chronic pain conditions.

5.Promotion of wound healing:  Retatrutide  has been shown to accelerate wound healing in animal studies, suggesting that it could have potential as a therapeutic agent for promoting wound healing in humans.

Application

1.Retatrutide is often used in the pharmaceutical industry, weight losing, etc.

2.Retatrutide is a kind of peptide product.

3.Retatrutide acetate can inhibited GCGR, GIPR and GLP-1R.

4.Retatrutide acetate is activated by glucagon receptors resulting in significant weight loss and increased energy expenditure.

5.Retatrutide acetate can be used in studies of obesity.

Q1: May I get one sample before placing order?

Re: Yes, Sample are available. For normal products, samples are for free and you just need to bear the freight; For those high value products, you just need to freight and certain product cost. When we both cooperate for some times or when you are our VIP customer, free sample will be offered when you need.

Q2: Which payment is available for your company?

Re: T/T, PayPal,bank transfer etc. You can choose the one which is convenient for you.

Q3: How and when can I get my goods after payment?

Re: For small quantity products, they will be delivered to you by international courier(DHL, FedEx, TNT etc.) or by air. Usually it will cost 5-7days that you can get the goods after delivery.For large quantity products, shipping by see is worthwhile.It will cost 15 to 30 days to come to your destination port, which depends on where the port is.

Q4: Is there any possible to use my appointed label or package?

Re: Yes. If needed, we'd lik

Synpeptide Co., Ltd, established in 2013, is a pioneering force in the biotechnology sector. At the core of our operations is the unwavering commitment to our guiding principles: "Quality First, Service Supreme."

Company Overview:
Founded in 2013 and headquartered in Nanjing, our company has been a trailblazer in the field of biotechnology. We pride ourselves on our dedication to delivering cutting-edge products and unparalleled services.

Business Philosophy:
"Quality First, Service Supreme" encapsulates our business philosophy. We firmly believe that prioritizing quality in all aspects of our operations and providing exceptional service form the foundation for enduring success.

Key Products:
Our primary focus encompasses a range of products, including weight loss peptides, medicinal peptides, cosmetic peptides, and customized peptides. Notable among our weight loss peptide offerings are Semaglutide, Tirzepatide, Retatrutide, and others.

Mission:
Our mission is to spearhead advancements in biotechnology by consistently upholding the highest standards of quality and service. Through innovation and excellence, we aim to contribute to the betterment of global health and well-being.

Customized Peptides:
In addition to our standard product line, we specialize in crafting customized peptides tailored to meet the unique needs of our diverse clientele.

Future Vision:
As we move forward, Synpeptide Co., Ltd. is poised for continued growth and innovation. We are committed to expanding our product portfolio, staying at the forefront of technological advancements, and exceeding the expectations of our valued clients.

At Synpeptide Co., Ltd, we are not just shaping the future of biotechnology; we are pioneering a path towards a healthier and more sustainable world.