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Retatrutide CAS:2381089-83-2 The factory directly produces purity of 99+%We supply freeze-dried powder and raw mate buy - image1

Retatrutide CAS:2381089-83-2 The factory directly produces purity of 99+%We supply freeze-dried powder and raw mate buy - image2

Retatrutide CAS:2381089-83-2 The factory directly produces purity of 99+%We supply freeze-dried powder and raw mate buy - image3

Retatrutide CAS:2381089-83-2 The factory directly produces purity of 99+%We supply freeze-dried powder and raw mate buy - image4

Retatrutide CAS:2381089-83-2 The factory directly produces purity of 99+%We supply freeze-dried powder and raw mate

Name: Retatrutide CAS:2381089-83-2 The factory directly produces purity of 99+%We supply freeze-dried powder and raw mate
Brand: zwxs
SKU: pr2607292980
Price: 40 USD
Availability: InStock

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$40-41/MT FOB

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CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shenzhen

Brand:

zwxs

Packaging:

15mg/vial; 10vials/box

Price valid (until):

2028-02-05

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Jinan Zhiwenxinsheng Electric Technology Co., Ltd.

Company Type:

Trader

Location:

China

Qualification:

Main Products:

peptides

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Sales manager:Kate
whatsapp：+8618562300759
Email:zwxs2@zwxstech.com

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Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.

In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.

Retatrutide, LY3437943

CAS#: 2381089-83-2

Molecular Formula: C221H342N46O68

Molecular Weight: 4731.33

Sequence: H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Appearance: White Powder

Purity (HPLC): ≥99.0%

Single Impurity (HPLC): ≤1.0%

Sodium Content (HPLC): 5.0%-12.0%

Moisture Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Storage: Store at 2-8 degrees Celsius in a dry and cool place.

Packaging: 1g-1kg, plastic bottle

Intended Use: For scientific research purposes

Product name	Retatrutide
Appearance	white powder
Specification	10mg/vial, 15mg/vial,20mg/vial, 30mg/vial, 40mg/vial, 50mg/vial, 60mg/vial
Package	10 vials/box
Origin	China
Storage method	cool dry place
purity	More than 99%
shelf life	2 years

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Product Application

1.Helps slow food leaving your stomach

2.Helps prevent your liver from making too much sugar
3.Helps the pancreas produce more insul when your blood sugar levels are high
4.Can help control blood glucose
5.Can reduce hyperglycemia, especially after meals
6.Can reduce fasting insul and fasting glucose
7.Can reduce hemoglobin A1c
8.Can decrease appetite and caloric intake, while inhibiting weight gain
9.Has been shown to lower triglyceride levels and oxidative stress from high LDL

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Peptide Storage Guidelines: General Tips

When storing peptides, remember to:
• Store peptide in a cold, dry, dark place
• Avoid repeated freezing and thawing of peptide
• Avoid overexposure to the air
• Avoid light exposure
• Avoid storing peptides in solution long term
• Aliquot peptide according to experimental requirements

Customer feedback

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Company Profile

Our company is a modern advanced enterprise specializing in production and exportation of APIs, Pharmaceutical intermediates, plant extracts etc. Our products are widely used in medicine, health care products, cosmetics, nutritional supplements and food additives areas. Our factory covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Since its establishment, the company has attached great importance to the team training and technical reform. Our modern production equipment guarantees for a fast and effective production with a superior degree of accuracy throughout the whole production line, everything is done in-house, processing, extraction, packaging and transportation of all links, ensuring maximum quality and efficiency. We are constantly research and development new ingredients and innovative new products, have earned the respect & Admiration from the worldwide customers. After years of continuous development, company has been accumulated rich experience in international trade and customer resources, established a stable customer base and perfect marketing service network. In addition, the company has established long-term technical cooperation with experts and professors from many universities and research institutes in the province.

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Why choose us?

1. High quality standards: All ingredients are tested for purity and performance.

2. Competitive prices: We offer exceptional value without compromising quality.

3. Customization: Solutions tailored to your specific needs and formulations.

4. Reliable delivery: Timely and efficient transportation to ensure that your production schedule is met.

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ECHEMI Editorial Reference

Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.

Certificates

Basic Info

Product Name:

Retatrutide

Other Name:

Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

CAS No.:

2381089-83-2

Molecular Formula:

C221H342N46O68

Molecular Weight:

4731.33

EC Number:

200-001-8

Color/Form:

White lyophilized

Categories:

Bulk Drug Intermediates

Characteristics

Water Solubility:

Soluble in water (5mg/ml).

Storage Conditions:

-20°C

Critical Temperature & Pressure:

-20°C

Research

Class:

Triple agonist — GCGR, GIPR, GLP-1R

Status:

Investigational (Phase 3)

Mechanism:

Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

EC50 (Human GCGR):

5.79 nM

EC50 (Mouse GIPR):

0.191 nM

EC50 (Mouse GLP1R):

0.794 nM

EC50 (Mouse GCGR):

2.32 nM

EC50 (Human GLP1R):

0.775 nM

EC50 (Human GIPR):

0.0643 nM

Source:

Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

Clinical Development:

NCT04881760; NCT05882045; NCT06354660

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Jastreboff et al. (2023) — Phase 2 Trial; FDA Drugs@FDA

Disclaimer:

Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

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Seller Information

Business Type:
Trader

Main Products:
peptides

Location:
No. 41-9, Fenghuangshan Road, Beiyuan Street, Tianqiao District, Jinan City, Shandong Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
3

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
5-10

Year of Establishment:
2026

Jinan Zhiwen Technology Co., Ltd. is a professional manufacturer and supplier of pharmaceutical raw materials, peptide compounds and fine chemicals. We own standardized laboratories and complete quality inspection procedures, strictly testing every batch for purity and consistency. Our product portfolio covers hot‑sale peptide APIs, chemical intermediates for biomedical research. Serving clients worldwide, we provide custom synthesis, sample support, flexible order volumes and end‑to‑end supply‑chain solutions. Committed to quality‑first principle, we strive to become your long‑term and dependable partner for biochemical raw‑material procurement.

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:

Peak season lead time: within 3 Workday; Off season lead time: within 1 Workday

Inquiry History

6662 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Retatrutide 2381089-83-2	3 MT	Mar 28, 2026
United Kingdom	Retatrutide - 2381089-83-2	1 G	Feb 10, 2026
United States	Retatrutide CAS 2381089-83-2 10mg vial	20 MT	Mar 7, 2026
United States	Factory Retatrutide API 99% Purity CAS 2381089-83-2	5 KG	Nov 10, 2025
United Kingdom	Peptide powder Retatrutide 99% pure for Body building cas 2381089-83-2 Weight Loss Peptide with COA	1 MT	Mar 22, 2026
United States	2381089-83-2	100 G	Jul 14, 2026
United States	2381089-83-2	100 G	Feb 24, 2026
United States	2381089-83-2	100 MT	Dec 9, 2023
United States	Retatrutide 2381089-83-2	200 MG	May 16, 2026
United Kingdom	2381089-83-2 retatrutide	300 MG	Feb 13, 2026
United States	Retatrutide 2381089-83-2 wholesale	500 MT	Nov 3, 2023
United States	Retatrutide CAS 2381089-83-2 99%	10 PCS	Feb 21, 2026
Poland	CAS 2381089-83-2 (Custom Peptide)	40 MT	Apr 10, 2026
Austria	Peptide Retatruide CAS 2381089-83-2	100 MT	Apr 4, 2026
Austria	Retatrutide CAS 2381089-83-2 10mg vial	20 PCS	Feb 10, 2026
United States	Tirzepatide 99.9% Liquid 2381089-83-2 TeruiOP	1 MT	Sep 6, 2023
United States	Retatrutide/LY3437943/GIPR/GLP-1R 98% Powder 2381089-83-2 Senwayer	1 G	Sep 3, 2023
United States	GLP-1 / GIP Retatrutide cas 2381089-83-2	1 MT	Oct 16, 2024
United States	Retatrutide 99% High Quality CAS 2381089-83-2	1 G	Jan 23, 2026
United States	Injection Peptide Tirzepatide/Retatrutide/ Semaglutide Peptides CAS 2381089-83-2	10	Oct 21, 2023

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Retatrutide CAS:2381089-83-2 The factory directly produces purity of 99+%We supply freeze-dried powder and raw mate

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