BIBF-1120 (Nintedanib) RC10887
928326-83-4
Food Grade
99%
Royalchem
25kg/drum
Yes
2030-01-01
Pharmaceutical intermediates
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferenceBIBF 1120 is a triple kinase inhibitor blocking vascular endothelial growth factor receptor, PDGF receptor, and FGF receptor, which has a potential to inhibit tumor growth and pulmonary fibrosis.
ChEBI: Nintedanib is a member of the class of oxindoles that is a kinase inhibitor used (in the form of its ethylsulfonate salt) for the treatment of idiopathic pulmonary fibrosis and cancer. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor, a vascular endothelial growth factor receptor antagonist, a fibroblast growth factor receptor antagonist and an angiogenesis inhibitor. It is an aromatic ester, a methyl ester, a member of oxindoles, an enamine, an aromatic amine, an aromatic amide and a N-alkylpiperazine. It is a conjugate base of a nintedanib(1+).Basic Info-
Product Name:
BIBF-1120
Other Name:BIBF-1120;BIBF-1120(Vargatef);VARGATEF ( BIBF1120 );Vargatef Base or BIBF-1120;BIBF1120,BIBF-1120,Vargatef;VargatefTM BIBF;928326-83-4 BIBF-1120;CS-76
CAS No.:928326-83-4
Molecular Formula:C31H33N5O4
InChIKeys:InChIKey=XZXHXSATPCNXJR-ZIADKAODSA-N
Molecular Weight:539.633
Exact Mass:539.62
Categories:
Characteristics-
PSA:
94.2
XLogP3:1.89 (est)
Density:1.3±0.1 g/cm3
Melting Point:305C
Boiling Point:742.2±60.0 °C at 760 mmHg
Flash Point:402.7±32.9 °C
Refractive Index:1.658
Water Solubility:In water, 9.66 mg/L at 25 deg C (est)
Storage Conditions:Store at 25 deg C (77 deg F); excursions permitted to 15 deg to 30 deg C (59 deg to 86 deg F). Protect from exposure to high humidity and avoid excessive heat. If repackaged, use USP tight container.
Vapor Pressure:2.18X10-18 mm Hg at 25 deg C (est)
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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