MOTS-c Lyophilized Peptide Powder For Laboratory Research Only

   Detail  

Appearance: Powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Peptide Storage Guidelines: General Tips

When storing peptides, remember to:

• Store peptide in a cold, dry, dark place
• Avoid repeated freezing and thawing of peptide
• Avoid overexposure to the air
• Avoid light exposure
• Avoid storing peptides in solution long term
• Aliquot peptide according to experimental requirements

Product Application

• 1. • How MOTS-c Helps
       We know that mitochondria are the main cellular sites devoted to ATP (energy) production and fatty acid oxidation. The Mitochondrial-Derived Peptide MOTS-c promotes metabolic homeostasis and reduces obesity and resistance. Mitochondria also play a crucial role in determining metabolic flexibility.

       MOTS-c in Osteoporosis
       Osteoporosis is a multi-factor and age-related metabolic disease. Bone mesenchymal stem cells (BMSCs) are the progenitor cells of osteoblasts and adipocytes and play an essential role in the process of bone formation.

       can stimulate the proliferation, differentiation and mineralization of osteoblasts, which exerts an important role in the cellular functions of osteoblasts. Osteoblasts are cells that make bone. Bone mass is maintained by a balance between the activity of osteoblasts that form bone and other cells called osteoclasts that break it down.

       Studies show that BMSC's treated with MOTS-c upregulated expression levels of ALP, Bglap, and Runx2. This resulted in the formation of mineralized nodules, indicating the osteogenic capacity of BMSC's regulated by MOTS-c. In simple nonscientific terms, MOTS-c promotes cell differentiation of BMSCs to osteoblasts = bone formation.

       MOTS-C BENEFITS
       *Promotes fatty acid metabolism in the liver
       *Promotes metabolic flexibility and homeostasis
       *Helps regulate mitochondrial energy
       *Protects against age and diet dependent resistance and obesity
       *Helps with weight loss
       *Promotes resistance to metabolic stress
       *Improves exercise capacity
       *Helps prevent osteoporosis
       *Improves glucose regulation
       *Promotes cell differentiation to form osteoblasts

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