N-Acetyl Epitalon Amidate /99% purity/5mg NET5/ Anti-aging

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•    Basic Origin: It is derived from Epitalon. Epitalon is a synthetic tetrapeptide composed of four amino acids (alanine, glutamic acid, aspartic acid, and glycine, abbreviated as AEDG). Its development was inspired by Epithalamin, a naturally occurring polypeptide produced by the pineal gland.
•    Chemical Modification: N-Acetyl Epitalon Amidate is a modified derivative of the original Epitalon, achieved through acetylation and amidation. Its amino acid sequence is N-Acetyl-Ala-Glu-Asp-Gly-NH2 (Ac-AEDG-NH2), with a molecular formula of C16H25N5O9 and a molecular weight of approximately 431.40.
•     Purpose of Modification: This dual modification provides it with superior stability compared to the original Epitalon. It makes the peptide more resistant to enzymatic degradation, thereby exhibiting enhanced characteristics in both in vivo and in vitro studies.

•    Telomerase Activation and Telomere Elongation: This is its core research mechanism. Studies indicate that Epitalon can stimulate the production of telomerase, promoting telomere elongation. This enables cells to surpass their normal division limit (the Hayflick limit), thereby delaying cellular senescence.
•     Neuroprotection and Cognitive Health: It is capable of crossing the blood-brain barrier, stimulating neurogenesis, and increasing the levels of DNA-binding proteins closely associated with learning and memory, such as phospho-CREB.
•     Potent Antioxidant and Anti-inflammatory Effects: It can directly scavenge reactive oxygen species (ROS) and reactive nitrogen species (RNS) in the body, reduce lipid peroxidation, protect mitochondria and DNA from oxidative damage, and inhibit the NF-κB pathway, which drives inflammaging.
•    Regulation of Neuroendocrine and Immune Systems:
  •    Pineal Gland Regulation: Promotes the synthesis and secretion of melatonin, restoring circadian rhythms that become disrupted during aging.
  •    Gonadal and Adrenal Regulation: Reverses the age-related decline in sex hormones and inhibits the hyperactivation of the HPA axis to reduce excessive cortisol release.
  •    Immune Regeneration: Promotes the regeneration of the atrophied thymus, increases the quantity and activity of T lymphocytes and NK cells, and enhances overall immunity.

      The core principle for storing parenteral lyophilized powder is strict refrigeration and absolutely no freezing. Before reconstitution, it is generally stored in the dark at 2 to 8°C. Once mixed and dissolved with the solvent, it must be used within a very short period.

Before Reconstitution (Original Packaging)

Strict Refrigeration: The vast majority of parenteral lyophilized powders need to be stored in a refrigerator at 2 to 8°C.

Absolutely No Freezing: Freezing will cause irreversible damage to the structure of proteins and peptides.

Protection from Light and Moisture: The product must be kept in its original packaging to avoid direct sunlight and accidental exposure to moisture.

After Reconstitution (Mixed State)

Highly Time-Sensitive: Once the lyophilized powder is dissolved with a sterile solvent, the stability of the drug drops significantly. It usually needs to be administered immediately or within a very short window (e.g., a few hours).

No Prolonged Storage: Under no circumstances should the reconstituted solution be stored in the refrigerator for use the next day. This can easily lead to loss of efficacy or severe bacterial contamination.

 * We will ship your order within 24–48 hours after payment is received.

 * We have dedicated shipping routes, allowing us to select the fastest and safest carrier for your specific destination—including FedEx, UPS, China Post, and other international express services. The estimated delivery time is approximately 7–15 business days.

 * We will also track the logistics throughout the entire process and update the logistics information for buyers in real time.

          Our company is located in Zhejiang Province and is a Chinese enterprise specializing in the production of peptide products.We are not intermediaries or resellers; we are the original manufacturer. This allows us to offer you the most competitive pricing. Our motto is: to manufacture products with care and serve customers with dedication.We are dedicated to serving every visitor with heart. No matter where you come from, you will experience our premium VIP service. We guarantee that every customer receives only the finest products, backed by exceptional after-sales support, as we strive to ensure your complete satisfaction.

1. What's the payment methods?
We could accept pay through Alipay, USDT, BTC and TT.

2.Does the product have a test report?
Each batch of our products undergoes testing before leaving the factory, and a Certificate of Analysis (COA) report is issued.

3.Can customers customize their own labels?

Custom labeling services are available. Please contact us to discuss your specific requirements prior to placing an order.

4.What is the product's shelf life?

When unopened, our products have a shelf life of two years under both room temperature and frozen storage conditions. Therefore, you can rest assured that extended shipping times will not cause the product to expire or degrade.

1.  * Ultra-High Purity Guaranteed
   Every batch is synthesized and purified to >99% purity, delivering the reliability and reproducibility your sensitive experiments demand.
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3. * Precision Dosing & Batch Consistency
   Peptides are accurately weighed and vacuum-sealed under sterile conditions. We enforce rigorous quality control to ensure unwavering consistency from batch to batch.
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5. * Endotoxin-Free & Sterile Assurance
   Produced in a certified cleanroom, our peptides are rigorously tested to be free of endotoxins, microbes, and impurities—safeguarding the integrity of your cell-based and in vivo studies.