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Triiodo L thyronine buy - large image1
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Triiodo L thyronine

4 Inquiries

Unit Price:

$40-46/MT FOB

Get Latest Price
CAS No.:

6893-02-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

china

Packaging:

100mg

Price valid (until):

2026-09-10

Company Type:
Trader
Location:
United States
Qualification:
Main Products:

peptides

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


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    Items Specifications
    Triiodo-L-thyronine 1g

    Description

    Application

    3,3′,5-Triiodo-L-thyronine can be used for Insulin-like growth factor I assays performed by using a double antibody radioimmunoassay. The product can also be used for  in vitrotransfection of 293T cells.

    Biochem/physiol Actions

    3,3′,5-Triiodo-L-thyronine also referred to as O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine or T3 is the biologically active thyroid hormone. In hypothyroidism pateints, triiodothyronine enhances mood and neuropsychological function. The product also positively regulates the hepatic FGF21 expression and stimulates the metabolic breakdown of glucose, fats, and proteins by enhancing the levels of numerous metabolic enzymes such as hexokinase, liver glucose 6-phosphatase as well as mitochondrial enzymes for oxidative phosphorylation. Additionally, the product facilitates the normal body growth in children and is pivotal for central nervous system maturation in foetus. 

    Preparation Note

    3,3′,5-Triiodo-L-thyronine dissolves in 4M NH4OH in MeOH at 5 mg/ml to yield a colorless to light yellow, clear to very slightly hazy solution.





    ECHEMI Editorial Reference
    3,3',5-Triiodo-L-thyronine is a potent agonist of thyroid hormone receptors TRα and TRβ with Kis of 2.3 nM.
    Crystalline T3 (liothyronine sodium, Cytomel) has a rapid onset and short duration of action. It is the therapy of choice when it is desirable to have rapid onset or cessation of activity, such as in patients with heart disease.
    Off-White Solid
    ChEBI: An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxi e in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
    Likely impurities are as in thyroxine. Purify it by dissolving in dilute NH3 at ~20o, then crystallise it by addition of dilute acetic acid to pH 6. Alternatively 35g are purified by dissolving it in a mixture of EtOH (250mL) and 2N NaOH (100mL), then hot 2N HCl is added to the boiling solution until the pH is 4-5. After cooling for a few hours, the solid is filtered off and dried in a vacuum [m 233-235o(dec)]. [Chambers et al. J Chem Soc 2433 1949, Beilstein 14 III 1566, 14 IV 2373.]

    Basic Info
    Product Name:

    3,3',5-Triiodo-L-thyronine

    Other Name:

    L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo- (9CI);NSC 80203;Thyronine, 3,3',5-triiodo-, L- (6CI);IODOTHYRONINE;3,3,5-TRIIODO-L -THYRONINE 95-98% FREE ACID CRYSTALLINE;O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine;3,3μ,5 Triiodothyronine (T3);3,3μ,5-Triiodo-L-thyronine, Liothyronine, T3, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine

    CAS No.:

    6893-02-3

    Molecular Formula:

    C15H12I3NO4

    InChIKeys:

    AUYYCJSJGJYCDS-LBPRGKRZSA-N

    Molecular Weight:

    650.97

    Exact Mass:

    650.97

    BRN:

    2710227

    EC Number:

    229-999-3

    Color/Form:

    Off-white to pale yellow

    HScode:

    29225090

    Characteristics
    PSA:

    92.8

    XLogP3:

    1.7

    Appearance:

    Off-white to pale yellow powder

    Density:

    2.2155 (estimate)

    Melting Point:

    234-238 °C(lit.)

    Boiling Point:

    232°C (rough estimate)

    Flash Point:

    294.6±30.1 °C

    Refractive Index:

    1.763

    Water Solubility:

    Insoluble in water, ethanol and propylene glycol. Soluble in dilute alkalies.

    Storage Conditions:

    −20°C

    Toxicity:

    LDLo oral in rat: 7500mg/kg

    Specific rotation:

    23 º (c=2 in ethanol)

    PKA:

    pKa 8.5 (Uncertain);8.4 (Uncertain);8.45 (Uncertain)

    Critical Temperature & Pressure:

    -20°C

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Commercially available liothyronine sodium tablets should be stored in tight containers at a temperature less than 40 deg C, preferably between 15-30 deg C. Commercially available liothyronine sodium injection should be stored at 2-8 deg C. Liothyronine sodium

  • Seller Information
    Business Type:

    Trader

    Main Products:

    peptides

    Location:

    126 AUTUMN ROAD ,LAKEWOOD NEW JERSEY

    Payment Terms:

    TT against copy of documents,100% TT in advance

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    51-100

    Year of Establishment:

    2023

    Certifications:

    certifacate for peptieds

  • Inquiry History
    4 Inquiries
    Country Product Purchase Quantity Date Posted
    United Kingdom

    L-Triiodothyronine

    10 G Jan 27, 2026
    Italy

    Liothyronine

    200 MG Nov 19, 2024
    United States

    Triiodo-L-thyronine

    100 PCS Aug 11, 2026
    Italy

    Lt3

    100 MG Nov 29, 2024
    Post an enquiry for this product
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