—— Product Specifications ——
—— Product Detail ——
Product Overview
Poly(deoxyadenylic-thymidylic) acid sodium salt [poly(dA-dT)·Na] is a synthetic alternating copolymer of deoxyadenylic and thymidylic acids with the molecular formula (C₁₀H₁₁N₅O₆P·C₁₀H₁₃N₂O₇P)ₙ·xNa and a molecular weight of approximately 1,000-10,000 Da. This white to off-white fibrous powder is a valuable tool in nucleic acid research, used as a substrate for studying DNA polymerases, nucleases, and other DNA-modifying enzymes. Its defined sequence provides a model system for investigating DNA structure, dynamics, and protein-DNA interactions.
Synthetic Process
Poly(dA-dT) is synthesized through the following routes:
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Enzymatic synthesis: DNA polymerase is used to synthesize the alternating copolymer from dATP and dTTP in a template-independent or template-dependent reaction.
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Purification: The crude product is purified by precipitation, dialysis, and chromatography.
Mechanism of Action / Application Principles
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Enzyme Studies: Used as a substrate for studying DNA polymerases, nucleases, and other DNA-modifying enzymes.
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Structural Studies: Used as a model system for investigating DNA structure and dynamics.
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Biophysical Chemistry: Used in studies of DNA-protein interactions and DNA conformation.
Quality Specifications
| Parameter | Specification |
| Assay | ≥98.0% |
| Appearance | White to off-white fibrous powder |
| Molecular Weight | ~1,000-10,000 Da |
| Sodium Content | ~6-12% |
| A260/A280 Ratio | ≥1.8 |
| Loss on Drying | ≤5.0% |
Each batch is accompanied by a Certificate of Analysis (COA).
Packaging & Storage
Storage conditions: Store in a tightly sealed container at -20°C, protected from light. Under recommended conditions, shelf life is 24 months.
— C ompany Profile ——
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Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.
Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.
We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.
To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.
Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.
—— Q&A ——
Q1: How to confirm the product quality before placing orders?
A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.
Q2: Can you supply free samples?
A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.
Q3: How do you treat quality complaints?
A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.
Q4: What is your MOQ? Is there a discount?
A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantities, we always support with better prices.
Q5: How to start orders or make payments?
A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.