Ara-290/ 99% purity/ 10mg RA10/ Anti-inflammatory and Tissue Protection

Add to WhatsApp: +85244962136 Amy  

I will provide you with more comprehensive information.

        Simply send us a message with the quantity you need. I will calculate the price and offer you a special discount. Once payment is confirmed, we will prioritize your order for immediate dispatch.

•           ARA-290 (officially known as Cibinetide) is a synthetic 11-amino-acid peptide. It is a non-erythropoietic derivative based on the three-dimensional structure of erythropoietin (EPO).
          Unlike traditional EPO, ARA-290 does not stimulate red blood cell production (i.e., it lacks hematopoietic activity). Instead, it selectively binds to the Innate Repair Receptor (IRR) in the human body. By activating this receptor, ARA-290 exerts potent anti-inflammatory and tissue-protective effects.
  Core Functions and Clinical Applications of ARA-290
         The core mechanism of ARA-290 is to transform the pro-inflammatory and tissue-damaged microenvironment in the body into a state conducive to healing and tissue repair. Its primary functions are concentrated in the following areas:
  1. Treatment of Small Fiber Neuropathy (Core Application)
        This is currently the primary research and application direction for ARA-290. Small fiber neuropathy leads to neuropathic pain, sensory abnormalities, and autonomic nervous system dysfunction.
  • For Sarcoidosis: Clinical trials have shown that  ARA-290 can significantly improve neuropathy symptoms in sarcoidosis patients, increase corneal small nerve fiber density, and enhance patients' exercise capacity.
  • For Type 2 Diabetes (T2D): In diabetic painful neuropathy, ARA-290 has also demonstrated the ability to significantly alleviate neuropathic pain, promote nerve fiber regeneration, and improve metabolic indicators (such as HbA1c and lipid profiles).
  2. Potent Anti-inflammatory and Neuroprotective Effects
  ARA-290 can inhibit inflammatory responses in both the central and peripheral nervous systems. In animal models, it effectively attenuates the overactivation of microglia in the spinal cord, thereby providing long-term relief from neuropathic pain and reducing the severity of inflammation in multiple sclerosis (EAE models).
  3. Promoting Wound Healing and Tissue Repair
  In ischemic or diabetic models, ARA-290 has shown the potential to promote angiogenesis, accelerate wound re-epithelialization, and enhance wound healing strength.
  4. Other Potential Tissue Protection
  
• Extensive preclinical studies indicate that ARA-290 exhibits the ability to prevent tissue damage and activate healing processes in various disease models, including myocardial infarction, chronic heart failure, burns, traumatic brain injury, and ischemic retinopathy.

      The core principle for storing parenteral lyophilized powder is strict refrigeration and absolutely no freezing. Before reconstitution, it is generally stored in the dark at 2 to 8°C. Once mixed and dissolved with the solvent, it must be used within a very short period.

Before Reconstitution (Original Packaging)

Strict Refrigeration: The vast majority of parenteral lyophilized powders need to be stored in a refrigerator at 2 to 8°C.

Absolutely No Freezing: Freezing will cause irreversible damage to the structure of proteins and peptides.

Protection from Light and Moisture: The product must be kept in its original packaging to avoid direct sunlight and accidental exposure to moisture.

After Reconstitution (Mixed State)

Highly Time-Sensitive: Once the lyophilized powder is dissolved with a sterile solvent, the stability of the drug drops significantly. It usually needs to be administered immediately or within a very short window (e.g., a few hours).

No Prolonged Storage: Under no circumstances should the reconstituted solution be stored in the refrigerator for use the next day. This can easily lead to loss of efficacy or severe bacterial contamination.

 * We will ship your order within 24–48 hours after payment is received.

 * We have dedicated shipping routes, allowing us to select the fastest and safest carrier for your specific destination—including FedEx, UPS, China Post, and other international express services. The estimated delivery time is approximately 7–15 business days.

 * We will also track the logistics throughout the entire process and update the logistics information for buyers in real time.

          Our company is located in Zhejiang Province and is a Chinese enterprise specializing in the production of peptide products.We are not intermediaries or resellers; we are the original manufacturer. This allows us to offer you the most competitive pricing. Our motto is: to manufacture products with care and serve customers with dedication.We are dedicated to serving every visitor with heart. No matter where you come from, you will experience our premium VIP service. We guarantee that every customer receives only the finest products, backed by exceptional after-sales support, as we strive to ensure your complete satisfaction.

1. What's the payment methods?
We could accept pay through Alipay, USDT, BTC and TT.

2.Does the product have a test report?
Each batch of our products undergoes testing before leaving the factory, and a Certificate of Analysis (COA) report is issued.

3.Can customers customize their own labels?

Custom labeling services are available. Please contact us to discuss your specific requirements prior to placing an order.

4.What is the product's shelf life?

When unopened, our products have a shelf life of two years under both room temperature and frozen storage conditions. Therefore, you can rest assured that extended shipping times will not cause the product to expire or degrade.

1.  * Ultra-High Purity Guaranteed
   Every batch is synthesized and purified to >99% purity, delivering the reliability and reproducibility your sensitive experiments demand.
2.  * Precision Dosing & Batch Consistency
   Peptides are accurately weighed and vacuum-sealed under sterile conditions. We enforce rigorous quality control to ensure unwavering consistency from batch to batch.
3.  * Endotoxin-Free & Sterile Assurance
   Produced in a certified cleanroom, our peptides are rigorously tested to be free of endotoxins, microbes, and impurities—safeguarding the integrity of your cell-based and in vivo studies.