rifampicin Harmless
2 Inquiries
13292-46-1
Pharmaceutical Grade
99%
shenzhen
Fying
10g/1kg/ 10kg/ 25kg
2026-09-17
vitamin
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceRed to Orange Crystalline SolidChEBI: A member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei)
Rifampin (also referred to as rifampicin) is a macrocyclic antibiotic with major activity against mycobacteria, commonly used in combination with other agents as therapy of tuberculosis. Rifampin is associated with transient and asymptomatic elevations in serum aminotransferase and bilirubin levels and is a well known cause of clinically apparent, acute liver disease that can be severe and even fatal.|A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)
Rifampicin is a semisynthetic derivative of rifamicin B, a macrolactam antibiotic and one of more than five antibiotics from a mixture of rifamicins A, B, C, D, and E, which is called a rifamicin complex, which is produced by actinomycetes Streptomyces mediteranei (Nocardia mediteranei). It was introduced into medical practice in 1968. Synthesis of rifampicin begins with an aqueous solution of rifamicin, which under the reaction conditions is oxidized to a new derivative of rifamicin S (32.7.4), with the intermediate formation of rifamicin O (32.7.3). Reducing the quinone structure of this product with hydrogen using a palladium on carbon catalyst gives rifamicin SV (32.7.5). The resulting product undergoes aminomethylation by a mixture of formaldehyde and pyrrolidine, giving 3-pyrrolidinomethylrifamicin SV (32.7.6). Oxidizing the resulting product with lead tetracetate to an enamine and subsequent hydrolysis with an aqueous solution of ascorbic acid gives 3-formylrifamicin SV (32.7.7). Reacting this with 1-amino-4-methylpiperazine gives the desired rifampicin (32.7.8).
Red to Orange Crystalline Solid
Eppendorf Tubes are the perfect option for working with medium-sized sample volumes!Maximum safety and stability for centrifugation up to 25,000 × gConical bottomsEasier processing of samples up to 5.0 mLHigher yields in DNA isolation, prep of mastermixes and buffers, and safe cell and tissue lysisTransparent polypropylene, free of plasticizers, biocides or mold release agentsHinged lid for minimized sample evaporation during storage and incubation in a wide range of temperatures from -86°C to 80°CBasic Info-
Product Name:
Rifampicin
Other Name:,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,1///;2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2-h)-dione,5,6;3-(((4-methyl-1-piperazinyl)imino)methyl)-rifamyci;3-((4-methyl-1-piperazinyl)iminomethyl)rifamycinsv;8-(((4-methyl-1-piperazinyl)imino)methyl)rifamycinsv;8-(4-Methylpiperazinyliminomethyl)rifamycinSV;8-(n-(4-methyl-1-piperazinyl)formidoyl)-rifomycins;RIFAMPIN ''LEPETIT''
CAS No.:13292-46-1
Molecular Formula:C43H58N4O12
InChIKeys:JQXXHWHPUNPDRT-WLSIYKJHSA-N
Molecular Weight:822.94
Exact Mass:822.94
BRN:5723476
EC Number:236-312-0
DSSTox ID:DTXSID6021244
Color/Form:faint red to very dark red
ATC Code:J - Antiinfectives for systemic use
HScode:29419000
Categories:
Characteristics-
PSA:
220
XLogP3:2.7
Appearance:faint red to very dark red crystalline
Density:1.1782 (rough estimate)
Melting Point:183°C (dec.)
Boiling Point:761.02°C (rough estimate)
Flash Point:561.3±34.3 °C
Refractive Index:1.6000 (estimate)
Water Solubility:Soluble in DMSO or methanolSoluble in water, ethyl acetate, chloroform, methanol, tetrahydrofuran and dimethyl sulfoxide.
Storage Conditions:2-8°C
Vapor Pressure:3.1X10-34 mm Hg at 25 °C /Estimated/
Toxicity:In the acute overdose setting, the mechanism of toxicity is not defined. A number of toxic reactions occurring with intermittent dosing schedules or on reexposure are postulated to be due to the presence of antirifampin antibodies.
Odor:ODORLESS
PKA:1.7, 7.9(at 25℃)
Henrys Law Constant:Henry's Law constant = 2.7X10-42 atm-cu m/mol at 25 °C /Estimated/
Dissociation Constants:Zwitterion with pKa 1.7 related to the 4-hydroxy and pKa 7.9 related to the 3-piperazine nitrogen
Experimental Properties:Very stable in DMSO; rather stable in water.|Hydroxyl radical reaction rate constant = 5.1X10-10 cu cm/molecule-sec at 25 °C /Estimated/
Critical Temperature & Pressure:2-8°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Rifampin capsules should be stored in tight, light-resistant containers at a temperature of 30 deg C or less, preferably between 15-30 deg C. The capsules should not be exposed to excessive heat.
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Seller Information
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Business Type:
Trader
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Main Products:
vitamin
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Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
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Average lead Time:
25
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Less than 5
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Year of Establishment:
2023
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
Philippines
Rifampicin
100 G Jun 16, 2026 
United States
Rifampicin
100 G May 28, 2025 Post an enquiry for this product
