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3554 Inquiries
2381089-83-2
Industrial Grade
98%
China
...
10/20/30/40/50mg Bottle
Yes
2026-09-19
Semaglutide,Tirzepatide,Retatrutide,Pharmaceutical Peptide,Cosmetic peptide
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceRetatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.
Retatrutide (LY-3437943) was discovered by the American pharmaceutical company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors) for obesity. The 2024 Lasker~DeBakey Clinical Medical Research Award has been given to Joel Habener and Svetlana Mojsov for their discovery of a new hormone GLP-1(7-37) and to Lotte Knudsen for her role in developing sustained acting versions of this hormone as a treatment for obesity.Basic Info-
Product Name:
Retatrutide
Other Name:Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide
CAS No.:2381089-83-2
InChIKeys:MLOLQJNKXBNWFW-SAGGEDDASA-N
Molecular Weight:0
EC Number:200-001-8
Color/Form:White lyophilized
Categories:
Characteristics-
Water Solubility:
Soluble in water (5mg/ml).
Storage Conditions:-20°C
Critical Temperature & Pressure:-20°C
Research-
Class:
Triple agonist — GCGR, GIPR, GLP-1R
Status:Investigational (Phase 3)
Mechanism:Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.
EC50 (Human GCGR):5.79 nM
EC50 (Mouse GIPR):0.191 nM
EC50 (Mouse GLP1R):0.794 nM
EC50 (Mouse GCGR):2.32 nM
EC50 (Human GLP1R):0.775 nM
EC50 (Human GIPR):0.0643 nM
Source:Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI
Clinical Development:
References-
ChEMBL:DrugBank:KEGG DRUG:PubChem:Disclaimer:
Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
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Seller Information
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Business Type:
Trader
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Main Products:
Semaglutide,Tirzepatide,Retatrutide,Pharmaceutical Peptide,Cosmetic peptide
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Location:
Hong Kong
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Year of Establishment:
2026
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Inquiry History3554 Inquiries
Country Product Purchase Quantity Date Posted
United States
Factory Retatrutide API 99% Purity CAS 2381089-83-2
5 KG Nov 10, 2025
United States
2381089-83-2
100 G Jul 14, 2026
United States
Retatrutide 99% High Quality CAS 2381089-83-2
1 G Jan 23, 2026
United States
GLP-1 / GIP Retatrutide cas 2381089-83-2
1 MT Oct 16, 2024
Hongkong, China
Retatrutide CAS 2381089-83-2 safe delivery strong Lyophilized powder Vial
20 Jan 25, 2026
Singapore
Factory 99% Purity Retatrutide Peptide CAS 2381089-83-2 Door-To-Door Service
100 MG Jun 28, 2025
United States
Retatrutide 99% White Powder CAS 2381089-83-2 High Quality Weight Loss Peptide
10 MT Dec 16, 2025
Canada
Janoshik Test Retatrutide 10mg Weight Loss GLP-1 Injection Peptide Retatrutide 2381089-83-2 99% Puri
1 MT Nov 12, 2024
United States
Retatrutide
5 G Jul 21, 2026
United States
Retatrutide
40 MG May 26, 2026
United States
Retatrutide
10 G Aug 7, 2026
Bolivia
retatrutide
20 MG May 26, 2026
United States
retatrutide
15 MG Apr 28, 2026
Mexico
Retatrutide
20 MG Jul 12, 2025
United Kingdom
retatrutide
40 MG Oct 11, 2025
United States
retatrutide
30 MG Nov 13, 2025
United States
Retatrutide
500 MG Apr 1, 2025
Canada
Retatrutide
120 MG Aug 4, 2025
Canada
Retatrutide
20 MG May 7, 2026
United Kingdom
Retatrutide
500 G Apr 17, 2025 Post an enquiry for this product
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