Imperatorin 98% Purity Furocoumarin Standard CAS 482-44-0 Research Grade Reference Standard

• • • • • Product Overview

          Imperatorin is a naturally occurring furocoumarin found in the roots of Angelica dahurica (Bai Zhi) and other plants such as Imperatoria ostruthium. It is one of the most abundant coumarins in Bai Zhi and serves as a key reference standard for the quality control of this traditional Chinese medicine. It is also known as Marmelosin or Pentosalen.

          With the molecular formula C₁₆H₁₄O₄ and a molecular weight of 270.28 g/mol, this compound appears as a white to off-white crystalline powder. It is soluble in methanol, ethanol, chloroform, and DMSO. The product is supplied at ≥98% purity as determined by HPLC analysis.

          Synthetic Process

          Imperatorin is obtained through isolation from plant sources:

          1. Extraction: Angelica dahurica roots or other plant materials are extracted with organic solvents.

          2. Chromatographic Separation: The extract is fractionated using silica gel column chromatography.

          3. Purification: Recrystallization or preparative HPLC yields the pure compound.

          4. Identity Confirmation: Structure is confirmed by NMR and mass spectrometry.

          Mechanism of Action & Applications

          This compound is primarily used as:

          • Reference Standard: For the quantification of furocoumarins in Bai Zhi and related products.

          • Quality Control : Used in the quality assessment of traditional Chinese medicines.

          • Method Development: Used in HPLC method validation.

          • Natural Product Chemistry: Serves as a reference for furocoumarin identification.

          Quality Specifications

          • Purity: ≥98.0% determined by HPLC.

          • Identity: Confirmed by NMR and mass spectrometry.

          • Loss on Drying: ≤1.0%.

          • Each batch is accompanied by a comprehensive COA.

          • Stable for 24 months when stored at 2-8°C in sealed containers, protected from light.

          Packaging & Storage

          • Standard packaging: 20mg, 50mg, 100mg amber glass vials.

          • Store at 2-8°C, protected from light and moisture.

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

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