 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > 1,1-Dimethylethyl (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate for Sale > tert-Butyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-(ats-10)

tert-Butyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-(ats-10)

2 Inquiries

Unit Price:

$15-19/KG FOB

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CAS No.:

125971-95-1

Port:

Shandong

Packaging:

25kg/bag

Price valid (until):

2026-09-25

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Shandong zhishang chemical Co.,Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Dichloromethane,Linocaine hydrochloride

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Atorvastatin Acetonide tert-Butyl Ester, also known as Atorvastatin Intermediate L-1, is a key protected intermediate in the commercial synthesis of Atorvastatin Calcium, the active ingredient in the widely prescribed lipid-lowering medication Lipitor. This compound is a complex chiral molecule with the molecular formula C₄₀H₄₇FN₂O₅ and a molecular weight of 654.82 g/mol . It features a fully substituted pyrrole core bearing a fluorophenyl group, an isopropyl group, a phenyl ring, and a phenylcarbamoyl moiety, which is attached via an ethyl linker to a 1,3-dioxane ring that contains the protected tert-butyl ester side chain . The structure contains two defined stereocenters at the 4 and 6 positions of the dioxane ring, designated as (4R,6R)

ECHEMI Editorial Reference

Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids[1].

Basic Info

Product Name:

1,1-Dimethylethyl (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate

Other Name:

1,3-Dioxane-4-acetic acid,6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-,1,1-dimethylethyl ester,(4R,6R)-;1,3-Dioxane-4-acetic acid,6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-,1,1-dimethylethyl ester,(4R-cis)-;1,1-Dimethylethyl (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate;1650552-85-4

CAS No.:

125971-95-1

Molecular Formula:

C40H47FN2O5

InChIKeys:

InChIKey=NPPZOMYSGNZDKY-ROJLCIKYSA-N

Molecular Weight:

654.810

Exact Mass:

654.81

EC Number:

603-106-0

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

78.79000

XLogP3:

7.78

Density:

1.1±0.1 g/cm3

Melting Point:

144-148ºC

Boiling Point:

678.0±55.0 °C at 760 mmHg

Flash Point:

363.9±31.5 °C

Refractive Index:

1.569

Vapor Pressure:

0mmHg at 25°C

See More 1,1-Dimethylethyl (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 1,1-Dimethylethyl (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Dichloromethane,Linocaine hydrochloride

Location:
BUILDING 1,HISENSE INTELLIGENCE VALLEY,NO.2116,OF PHOEIX ROAD, HIGH-TECH ZONE ,JINAN CITY ,SHANDONG PROVINCE,CHINA

Payment Terms:
D/P,L/C,D/A

Average lead Time:
15

Total Annual Revenue:
$10 million-$25 million

Total Employees:
11-50

Year of Establishment:
2016

Shandong zhishang chemical Co.,Ltd is a leading Manufactory supplier of Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1), Ethylene oxide-propylene oxide copolymer, Strontium carbonate based in Jinan, Shandong, China. With a commitment to quality and customer satisfaction, Shandong zhishang chemical Co.,Ltd has become a trusted name in the industry. Our product line includes a range of high-quality Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1), Ethylene oxide-propylene oxide copolymer, Strontium carbonate, which are available at competitive prices. Shandong zhishang chemical Co.,Ltd has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	tert-Butyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-	1000 KG	Aug 24, 2026
India	tert-Butyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-(ats-10)	1 MT	Aug 25, 2026

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More Choices Find All Products for Sale 

Product Name	Grade / Content	Supplier Name	Details
China Professional Manufacturer Supply Great Quality Atorvastatin Acetonide tert-Butyl Ester CAS 125971-95-1	Pharmaceutical Grade/99	LEADER BIOCHEMICAL GROUP	Inquiry
tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate	/99.00	HANGZHOU LEAP CHEM CO., LTD.	Inquiry
Atorvastatin Acetonide tert-Butyl Ester-a	/	Shaanxi Dideu Medichem Co. Ltd	Inquiry
125971-95-1 99% powder Professional Producer Greenbo	Pharmaceutical Grade/99	Greenbo Biochem	Inquiry
(4R-cis)-1,1-dimethylethyl-6-[2-[2-(4-fluorophenyl)-5-(1-isopropyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-	/	Hefei Heyu Chemical New Materials Co., Ltd	Inquiry