Product Detail  

Teriparatide Acetate (hPTH 1-34)

Basic Chemical Specifications

• CAS No.: 52232-67-4
• Alias: Recombinant Human Parathyroid Hormone (1–34), PTH(1-34)
• Amino Acid Count: 34 active N-terminal residues of full-length human PTH
• Molecular Weight: 4117.72 Da
• Appearance: White lyophilized crystalline powder
• Standard Vial Pack: 100mcg / 500mcg / 1mg / 2mg per sterile glass vial
• HPLC Purity: ≥99% research grade
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Product Introduction & Core Mechanism

1. Intermittent pulsatile administration drives net bone formation
   
   
   Short, daily transient exposure to Teriparatide preferentially stimulates osteoblast proliferation, inhibits osteoblast apoptosis, and upregulates IGF-1, FGF2 and collagen synthesis. This creates an anabolic window where bone generation outpaces bone breakdown, thickening trabecular bone, improving trabecular connectivity and increasing cortical bone mineral density.
2. Continuous sustained exposure triggers bone resorption
   
   
   Prolonged high PTH levels activate osteoclast overactivity to dissolve bone matrix, a key control contrast widely studied in osteoporosis, bone fracture healing and age-related bone loss lab models.
3. Calcium & phosphate homeostasis regulation
   
   
   Modulates renal calcium reabsorption and phosphate excretion, supporting research into hypocalcemia, parathyroid gland dysfunction and mineral metabolism disorders.
4. Fracture repair & skeletal regeneration
   
   
   Promotes angiogenesis and osteogenic differentiation at sites, commonly applied in preclinical studies of delayed bone union, post-skeletal trauma recovery and senile osteopenia.

Our Teriparatide Product Competitive Advantages

1. Ultra-high purity ≥99%
   
   
   Every batch undergoes HPLC full purity test and LC-MS full-sequence mass spectrometry verification. Complete COA, HPLC chromatogram, heavy metal and low-endotoxin test reports (third-party Janoshik testing available) are supplied for all bulk orders; no truncated peptide fragments, oxidation impurities or sequence mismatches.
2. Vacuum freeze-drying technology
   
   
   All moisture fully removed without preservatives to lock complete peptide biological activity. Lyophilized solid powder resists hydrolysis and oxidation during long-distance air & sea cross-border shipping, maintaining stable potency with a 24-month shelf life under proper dark cold storage.
3. GMP clean-room sterile production
   
   
   Individually sealed single vial packaging to avoid cross-contamination. Custom private labels, bottle sizes and bulk powder split packaging service available for global lab suppliers and bone research distributors.
4. Stable water solubility
   
   
   Rapidly dissolves in sterile bacteriostatic water to form clear, colorless sediment-free solution, ideal for precise low-dose preparation for in vitro cell culture and in vivo animal trials.
5. Complete professional technical support
   
   
   We supply detailed reconstitution guide, temperature storage rules, laboratory dosage reference data and full batch traceability documents for all partners.

Storage & Reconstitution Instructions

• Unopened lyophilized powder: Long-term storage at -20°C away from light and humidity, shelf life up to 24 months; short transit storage at 2–8°C is acceptable.
• Recommended solvent: Sterile bacteriostatic water
• Operation tip: Equilibrate vial to room temperature before opening; slowly inject solvent along the inner vial wall and swirl gently. Violent shaking triggers peptide aggregation and irreversible activity loss.
• Reconstituted liquid: Seal tightly and refrigerate at 2–8°C, finish all usage within 28 days; avoid repeated freeze-thaw cycles to prevent structural degradation.

Global Wholesale Cooperation Support

• Flexible minimum order quantity & tiered large-volume discount for stable VIP long-term partners
• Low-risk dedicated shipping lines for USA, EU, Brazil, Australia with reduced customs detention probability
• Exclusive one-on-one VIP account manager, fast working-hour response and professional reshipping solutions for logistics issues

Teriparatide Acetate (PTH 1-34) Lyophilized Peptide | 99% High Purity Bone Anabolic Research Peptide

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