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1,4-Benzodioxane-6-carboxaldehyde High Purity Organic Intermediate CAS 4612-26-4 Research Grade Reagent for Pharmaceutical and Organic Synthesis

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CAS No.:

4612-26-4

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

Packaging:

10g/vial, 25g/vial, 100g/vial, 500g/vial

Sample Available:

Yes

Price valid (until):

2026-09-27

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Jinan topfull chemical co.,ltd

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

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Product Details
Seller Information

Description

—— Product Specifications ——

Shop 1,4-Benzodioxane-6-carboxaldehyde High Purity Organic Intermediate CAS 4612-26-4 Research Grade Reagent for Pharmaceutical and Organic Synthesis-Detailed Image 1

—— Product Detail ——

- - - - Product Overview
        
        1,4-Benzodioxane-6-carboxaldehyde is an organic compound with the molecular formula C₉H₈O₃ and molecular weight of 164.16 g/mol. This white to light yellow crystalline solid is a valuable intermediate in pharmaceutical and organic synthesis. The compound features a benzodioxane core with an aldehyde substituent, enabling further functionalization through condensation, reduction, and oxidation reactions.
        
        Synthetic Process
        
        Formylation: 1,4-Benzodioxane is formylated using the Vilsmeier-Haack reaction or other formylation methods to introduce the aldehyde group at the 6-position
        
        Purification: The crude product is purified by recrystallization from suitable solvents
        
        Drying: The purified product is dried under vacuum
        
        Mechanism of Action
        
        Benzodioxane Core: The bicyclic structure provides rigidity and specific electronic properties
        
        Aldehyde Reactivity: The aldehyde group participates in condensation, reduction, and oxidation reactions
        
        Pharmaceutical Relevance: Benzodioxane derivatives exhibit various biological activities
        
        Research Applications & Market Significance
        
        Pharmaceutical Research: Building block for drug discovery programs
        
        Organic Synthesis: Versatile intermediate for functionalized benzodioxane derivatives
        
        Agrochemical Synthesis: Intermediate for pesticide development
        
        Material Science: Used in the preparation of specialty materials
        
        Quality Specifications
        
        Purity: ≥98.0% (HPLC)
        
        Melting point: 57-61°C
        
        Storage: 2-8°C, sealed, protected from light
        
        Stable for 24 months when properly stored
        
        Packaging & Shipping
        
        Research quantities: 10g, 25g amber glass vials
        
        Bulk quantities: 100g, 500g amber glass bottles
        
        Shipped at ambient temperature

— C ompany Profile ——

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

—— Q&A ——

Q1: How to confirm the product quality before placing orders?
A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

Q2: Can you supply free samples?
A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

Q3: How do you treat quality complaints?
A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

Q4: What is your MOQ? Is there a discount?
A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantities, we always support with better prices.

Q5: How to start orders or make payments?
A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.

ECHEMI Editorial Reference

1,4-Phenylenebisboronic acid is off-white powder

Certificates

Basic Info

Product Name:

1,4-Phenylenebisboronic acid

Other Name:

1,4-PHENYLENEBIS(BORONIC ACID);4-(DIHYDROXYBORYL)PHENYLBORONIC ACID;AKOS BRN-0002;P-PHENYLENEDIBORONIC ACID;1,4-Phenylenebisboronic;1,4-benzeendiboronic acid;1,4-Benzenediboronicacid,96%;enebisboronic acid

CAS No.:

4612-26-4

Molecular Formula:

C6H8B2O4

InChIKeys:

BODYVHJTUHHINQ-UHFFFAOYSA-N

Molecular Weight:

165.75

Exact Mass:

166.060867

BRN:

2836921

EC Number:

628-888-0

NSC Number:

25410

TSCA:

Color/Form:

white to off-white

HScode:

29310095

Categories:

Heterocyclic Ring

Characteristics

PSA:

80.9

XLogP3:

-2.95380

Appearance:

White to off-white crystalline solid, essentially no odor.

Density:

1.33±0.1 g/cm3(Predicted)

Melting Point:

>350 °C(lit.)

Boiling Point:

420.1±55.0 °C(Predicted)

Flash Point:

207.9±31.5 °C

Refractive Index:

1.555

Water Solubility:

Soluble in water 2.5%.

Storage Conditions:

0-6°C

PKA:

8.30±0.17(Predicted)

Critical Temperature & Pressure:

Keep in dark place,Sealed in dry,Room Temperature

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 1,4-Phenylenebisboronic acid Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

Location:
RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2022

Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
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1,4-Benzodioxane-6-carboxaldehyde High Purity Organic Intermediate CAS 4612-26-4 Research Grade Reagent for Pharmaceutical and Organic Synthesis

Product Details

Seller Information