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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Pomalidomide for Sale > Pomalidomide CAS 19171-19-8 Potent Cereblon E3 Ligase Modulator for Multiple Myeloma and Immuno-Oncology hfd
Pomalidomide CAS 19171-19-8 Potent Cereblon E3 Ligase Modulator for Multiple Myeloma and Immuno-Oncology hfd buy - large image1
Pomalidomide CAS 19171-19-8 Potent Cereblon E3 Ligase Modulator for Multiple Myeloma and Immuno-Oncology hfd buy - image1
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Pomalidomide CAS 19171-19-8 Potent Cereblon E3 Ligase Modulator for Multiple Myeloma and Immuno-Oncology hfd

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Unit Price:

$100-130/G FOB

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CAS No.:

19171-19-8

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

5g, 25g, 100g, 500g

Price valid (until):

2026-09-29

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    —— Product Specification ——

    Parameter Specification Details
    Product Name Pomalidomide 4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 
    CAS Number 19171-19-8 19171-19-8 
    Molecular Formula C₁₃H₁₁N₃O₄ — 
    Molecular Weight 273.24 g/mol — 
    Appearance Off-white to yellow powder Visual inspection 
    Purity ≥98.0% Determined by HPLC 
    Melting Point 318.5 – 320.5°C — 
    Boiling Point 582.9 ± 45.0°C (Predicted) — 
    Density 1.570 ± 0.06 g/cm³ (Predicted) — 
    Solubility DMSO: ≥14 mg/mL — 
    IC₅₀ (TNF-α) 13 nM Inhibits LPS-induced TNF-α release in PBMCs 
    Storage 2-8°C; DMSO solutions stable at -20°C for up to 1 month Sealed containers, protect from moisture and light 
    Packaging 5mg, 10mg, 25mg, 50mg, 100mg, 500mg, 1g Amber glass vials
    Application Research use only Oncology research, protein degradation studies


    —— Product Detail ——

    Product Overview

    • Pomalidomide (CAS 19171-19-8), also known as CC-4047 or Actimid, is a third-generation immunomodulatory drug (IMiD) derived from thalidomide . It appears as an off-white to yellow powder with the molecular formula C₁₃H₁₁N₃O₄ and a molecular weight of 273.24 g/mol . As the successor to lenalidomide, pomalidomide demonstrates significantly enhanced antitumor activity and is a core therapeutic agent for relapsed/refractory multiple myeloma . It is also a widely used cereblon (CRBN) ligand in PROTAC (Proteolysis-Targeting Chimera) technology for targeted protein degradation research .


    Packaging & Shipping

                  • Research quantities: 5mg, 10mg, 25mg amber glass vials

                  • Bulk quantities: 50mg, 100mg amber glass bottles

                  • Custom packaging available upon request

                  • Not classified as hazardous material for transport under normal conditions

                  • Product for research and analytical use only; not for human therapeutic use

    Shop CAS 18048-64-1 Eltrombopag Intermediate for Pharmaceutical Research  kr-Detailed Image 1

    Company profile ——


     Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 1

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

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    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    ECHEMI Editorial Reference
    Yellow SolidChEBI: An aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies.Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. In February 2013, the US FDA approved pomalidomide (also known as CC4047) for the treatment of multiple myeloma (MM) in patients with disease progression after receiving other cancer therapeut
    Pomalidomide is an aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies. It has a role as an antineoplastic agent, an immunomodulator and an angiogenesis inhibitor. It is a dicarboximide, a member of isoindoles, a member of piperidones and an aromatic amine. It derives from a thalidomide.|Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.|Pomalidomide is an immunomodulatory and antineoplastic agent that is used in the therapy of multiple myeloma. Pomalidomide, like the structurally related agents thalidomide and lenalidomide, is associated with a low rate of serum aminotransferase elevations during therapy and has been implicated in causing rare instances of clinically apparent liver injury which can be severe.|Thalidomide and its analogue lenalidomide are immunomodulatory and antineoplastic agents that are used in the therapy of multiple myeloma. Both agents are associated with a low rate of serum aminotransferase elevations during therapy and both have been implicated in causing rare instances of clinically apparent liver injury which can be severe.

    Certificates
    • Pomalidomide CAS 19171-19-8 Potent Cereblon E3 Ligase Modulator for Multiple Myeloma and Immuno-Oncology hfd Certificates 1 TDS

    Basic Info
    Product Name:

    Pomalidomide

    Other Name:

    1H-Isoindole-1,3(2H)-dione,4-amino-2-(2,6-dioxo-3-piperidinyl)-;Phthalimide,3-amino-N-(2,6-dioxo-3-piperidyl)-;4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione;4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione;CC 4047;Actimid;4-Amino-2-(2,6-dioxo-3-piperidinyl)isoindole-1,3-dione;Pomalidomide;4-Amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione;2-(2,6-Dioxopiperidin-3-yl)-4-amino-isoindole-1,3-dione;4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;Pomalyst;Imnovid;443912-23-0;443919-33-3

    CAS No.:

    19171-19-8

    Molecular Formula:

    C13H11N3O4

    InChIKeys:

    InChIKey=UVSMNLNDYGZFPF-UHFFFAOYSA-N

    Molecular Weight:

    273.24

    Exact Mass:

    273.24

    EC Number:

    1592732-453-0

    Color/Form:

    Solid yellow powder

    ATC Code:

    L04AX06|L - Antineoplastic and immunomodulating agents

    HScode:

    29251900

    Characteristics
    PSA:

    110

    XLogP3:

    0.2

    Appearance:

    yellow

    Density:

    1.570±0.06 g/cm3(Predicted)

    Melting Point:

    318.5 - 320.5°

    Boiling Point:

    582.9±45.0 °C(Predicted)

    Flash Point:

    306.3±28.7 °C

    Refractive Index:

    1.691

    Water Solubility:

    DMSO: ≥14mg/mL

    Storage Conditions:

    2-8°C

    Vapor Pressure:

    7.54X10-16 mm Hg at 25 deg C (est)

    Dissociation Constants:

    pKa1 = 1.56 (aromatic amine); pKa2 = 11.59 (secondary amide) (est)

    Experimental Properties:

    Henry's Law contant = 4.56X10-20 atm-cu m/mol at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Pakistan

    Pomalidomide

    1 KG May 27, 2025
    Pakistan

    Pomalidomide

    1 KG May 26, 2025
    Post an enquiry for this product
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