Mocetinostat 726169-73-9 SHAANXI DIDEU MEDICHEM CO.LTD Hot sell,99% high purity
TDS 5 Inquiries
726169-73-9
Pharmaceutical Grade
99%
SHAANXI
Dideu
25kg/Cardboard Drum
2026-10-02
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
-
Product Description
-
Seller Information
-
Inquiry History
-
DescriptionECHEMI Editorial ReferenceMocetinostat (MGCD0103) is a potent, orally active and isotype-selective HDAC (Class I/IV) inhibitor with IC50s of 0.15, 0.29, 1.66 and 0.59 μM for HDAC1, HDAC2, HDAC3 and HDAC11, respectively. Mocetinostat shows no inhibition on HDAC4, HDAC5, HDAC6, HDAC7, or HDAC8.
N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]benzamide is a member of benzamides.|Mocetinostat has been used in trials studying the treatment of Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma, among others.|Mocetinostat is a rationally designed, orally available, Class 1-selective, small molecule, 2-aminobenzamide HDAC inhibitor with potential antineoplastic activity. Mocetinostat binds to and inhibits Class 1 isoforms of HDAC, specifically HDAC 1, 2 and 3, which may result in epigenetic changes in tumor cells and so tumor cell death; although the exact mechanism has yet to be defined, tumor cell death may occur through the induction of apoptosis, differentiation, cell cycle arrest, inhibition of DNA repair, upregulation of tumor suppressors, down regulation of growth factors, oxidative stress, and autophagy, among others. Overexpression of Class I HDACs 1, 2 and 3 has been found in many tumors and has been correlated with a poor prognosis.CertificatesBasic Info-
Product Name:
Mocetinostat
Other Name:Benzamide,N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]-;N-(2-Aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]benzamide;MGCD 0103;Mocetinostat;MG 0103
CAS No.:726169-73-9
Molecular Formula:C23H20N6O
InChIKeys:InChIKey=HRNLUBSXIHFDHP-UHFFFAOYSA-N
Molecular Weight:396.452
Exact Mass:396.44
EC Number:232-668-6
UNII:A6GWB8T96J
DSSTox ID:DTXSID80222945
NCI Thesaurus Code:C62521
HScode:2933990090
Categories:
Characteristics-
PSA:
106
XLogP3:2.8
Density:1.3±0.1 g/cm3
Refractive Index:1.730
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
-
Location:
https://www.dideu.com/en/
-
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
-
Average lead Time:
7
-
Total Annual Revenue:
Above $100 million
-
Total Employees:
Above 1000
-
Year of Establishment:
2016
-
Certifications:
ISO Certificate,REACH
">Company Profile -
-
Inquiry History5 Inquiries
Country Product Purchase Quantity Date Posted
United States
Mocetinostat
1 G Sep 2, 2026
United States
Mocetinostat
4 G Aug 3, 2026
Thailand
Mocetinostat
2 G Jul 4, 2026
United States
Mocetinostat
2 G Mar 28, 2026
United States
Mocetinostat
2 G May 18, 2026 Post an enquiry for this product
- Hot Searches
- carbon black prices
- sodium carboxyl methyl cellulose distributor
- v2s5
- retatrutide sale online
- ammonium sulphate crystalline
- amoxicillin potassium clavulanate info
- reta for sale
- na 931 peptide for sale
- ethylene glycol price
- hexylene glycol sds
- radium radium
- where can you buy sulfur hexafluoride
