Aliskiren hemifumarate
173334-58-2
Pharma Grade
99%
DAHAI BIOCHEM
25kg/Cardboard Drum
2026-12-31
HARD FAT
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceAliskiren hemifumarate(CGP 60536) is a direct renin inhibitor with IC50 of 1.5 nM.IC50 value: 1.5 nM [1]Target: reninin vitro: Aliskiren hemifumarate appears to bind to both the hydrophobic S1/S3-binding pocket and to a large, distinct subpocket that extends from the S3-binding site towards the hydrophobic core of renin. Oral bioavailability of Aliskiren hemifumarate is 2.4% in rats, 16% in marmosets and about 2.5% in humans [2].in vivo: Aliskiren hemifumarate (< 10 mg/kg, oral) inhibitsBasic Info
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Product Name:
Aliskiren hemifumarate
Other Name:Benzeneoctanamide,δ-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,ζ-bis(1-methylethyl)-,(αS,γS,δS,ζS)-,(2E)-2-butenedioate (2:1);Benzeneoctanamide,δ-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,ζ-bis(1-methylethyl)-,[αS-(αR*,γR*,δR*,ζR*)]-,(E)-2-butenedioate (2:1) (salt);Benzeneoctanamide,δ-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,ζ-bis(1-methylethyl)-,(αS,γS,δS,ζS)-,(2E)-2-butenedioate (2:1) (salt);Aliskiren hemifumarate;Aliskiren fumarate
CAS No.:173334-58-2
Molecular Formula:C30H53N3O6.1/2C4H4O4
InChIKeys:RSFGNDXWVZPKJA-KVBHIGNWSA-N
Molecular Weight:551.75832
Exact Mass:1218.80000
EC Number:1308068-626-2
NSC Number:759185
Categories:
Characteristics-
PSA:
366.86000
XLogP3:9.88180
Melting Point:108-115 °C
Storage Conditions:Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Vapor Pressure:1.59E-23mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
Reproductive toxicity, Category 1B
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H360 May damage fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P203 Obtain, read and follow all safety instructions before use.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P318 IF exposed or concerned, get medical advice.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
HARD FAT
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Location:
BUILDING 4,NO.571, STR.19,BAIYANG DISTRICT, HANGZHOU,CHINA
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
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Total Annual Revenue:
Less than $1 million
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Total Employees:
5-10
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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