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Mazdutide 99% High Purity Mazdutide raw materials GLP-1 Weight Loss Peptides Cas 2259884-03-0 factory selling

Name: Mazdutide 99% High Purity Mazdutide raw materials GLP-1 Weight Loss Peptides Cas 2259884-03-0 factory selling
Brand: APKX
SKU: pr2609034405
Price: 20 USD
Availability: InStock

TDS 5 Inquiries

Unit Price:

$20-25/G FOB

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CAS No.:

2259884-03-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHENZHEN

Brand:

APKX

Packaging:

10 mg/vial

Price valid (until):

2027-01-01

Contact Supplier

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Tianjin Apex Import and Export Trading Co., Ltd.

Company Type:

Trader

Location:

China

Qualification:

Main Products:

peptides

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Product Description
Seller Information
Inquiry History

Description

Name:Windy
sales05@cnspks.com
WhatsApp：+852 9841 4845
WhatsApp：+86 190 3346 0040

Mazdutide, as a novel once-weekly GLP-1 and glucagon receptor dual agonist, offers a wide range of potential health benefits for research test subjects. From improving glucose control and aiding weight management to promoting cardiovascular health and preserving neurological function.
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Mazdutide is an innovative therapeutic agent with the following details:
English name: Mazdutide

CAS number: 2259884-03-0

Mazdutide is a GLP-1R/GCGR dual receptor agonist developed by Innovent Biologics, intended for the long-term weight management of adult patients with obesity or overweight.

Mechanism of Action

Mazdutide innovatively adopts a dual receptor agonist mechanism. On one hand, it activates GLP-1R to promote insulin secretion, suppress appetite, and delay gastric emptying, thereby reducing food intake. On the other hand, it activates GCGR to promote fat oxidation and energy expenditure. This two-pronged approach enhances the ability to reduce weight and regulate metabolism.

Weight Loss Efficacy

In the Phase II clinical trial of Mazdutide, patients in the 3mg, 4.5mg, and 6mg Mazdutide groups (administered once weekly) achieved an average weight reduction of 7.2%, 10.6%, and 11.6% respectively after 24 weeks of treatment. Results from the Phase III GLORY-1 trial showed that during the 48-week treatment period, the 6mg Mazdutide group had an average weight loss of 14.01%, while the placebo group only had a weight loss of 0.30%.

Improvement of Metabolic Indicators

Mazdutide not only effectively reduces weight but also comprehensively improves metabolic indicators. For example, in the Phase III clinical trial, the 6mg Mazdutide group saw an average reduction of 8.56mmHg in systolic blood pressure, a decrease of 0.65mmol/L in triglycerides, and a significant reduction in uric acid levels. Additionally, it showed a significant improvement effect on fatty liver, which can effectively reduce the pressure on the cardiovascular system and lower the risk of obesity-related complications.

Target Population

It is suitable for patients with simple obesity (BMI ≥ 28) and patients with a BMI of ≥ 24 who have one or more comorbidities, such as hyperglycemia, hypertension, dyslipidemia, fatty liver, and obstructive sleep apnea.

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1. How to make an order?

Send me message and let me know what you need with quantity , then i will calculate to you

2. What's the lead time and shipping ways?
We will delivery to the package by FEDEX express to you after receive your payment, it would take around 5-7 days to your address.

3. How do i keep the peptides when i receive it ?
Peptides in the form of lyophilized powder can be transported at room temperature by vacuum packaging, while polypeptides in the dissolved state need to be refrigerated at 2°C - 8°C. For long-term storage, peptides should be stored in the form of lyophilized powder store at -20°C or -80°C in a sealed container with desiccant, which can avoid the degradation of peptides to the greatest extent.

4. What's the payment methods?
We could accept pay through paypal,bank transfer, X-Transfer and bitcoin.
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——Handling and Storage——

Precautions for safe handling：Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.Conditions for safe storage, including any incompatibilitiesStore the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

——— Company Profile ———

We are a chemical manufacturer integrating production, processing and export, mainly dealing in pharmaceutical intermediates and various industrial chemicals. It has won praise from customers at home and abroad. We have also established an excellent professional sales team with rich international marketing experience, able to efficiently provide a range of products and professional services.

With synthetic biology platform technology as the core, it conducts innovative research and development, mainly engaged in the research and development of recombinantly expressed pharmaceutical peptides and proteins. Its products include innovative drugs, APIs, pharmaceutical and green synthetic industrial enzymes, functional peptides and protein products, etc.

At present, our company has realized the industrialization of a variety of biosynthetic peptide products and has obtained cooperation orders from many well-known domestic and foreign pharmaceutical companies.

Items	Specifications
	Independent vacuum packaging, white powder
	5mg10vials 10mg10vials 15mg10vials 20mg10vials 30mg10vials 40mg10vials 50mg*10vials
	Refrigeration treatment Shelf life: 3 years

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We offer various types of peptides, and we can provide excellent quality and preferential prices for peptides.

The feedback from customers who have ordered our products (peptides) is very good.

Reliable buyers around the world can contact us for peptide matters.

We believe that we offer an unparalleled combination of quality, performance and value. If you have any questions about this product or want to learn more about how it can benefit your business, please feel free to contact us. We are committed to providing excellent customer service and helping our customers achieve their business goals.Thank you for considering Jinbei. We look forward to the opportunity to work with you and help you succeed.

ECHEMI Editorial Reference

Mazdutide is a peptide-based GLP-1 and glucagon receptor (GCGR) dual agonist. As a pharmaceutical raw material, Mazdutide is characterized by its dual receptor activity and defined peptide structure. It is suitable for API research, analytical testing, pharmaceutical development, and related manufacturing processes.

Certificates

Basic Info

Product Name:

Mazdutide

Other Name:

Mazdutide;Mazdutide acetate;Mazdutide 10mg;Mazdutide 5mg 10mg;LY-3305677;Mazdutide (IBI-362;OXM-3)

CAS No.:

2259884-03-0

Molecular Weight:

EC Number:

884-103-0

Color/Form:

White to off-white

Categories:

Polypeptide

Research

Class:

Dual GLP-1R/GCGR agonist (long-acting peptide)

Status:

Investigational — Phase 3 (China)

Mechanism:

A long-acting dual agonist of the GLP-1 receptor (GLP-1R, Ki = 28.6 nM) and glucagon receptor (GCGR, Ki = 17.7 nM). The dual activation provides both glycemic control (via GLP-1R) and increased energy expenditure / hepatic lipolysis (via GCGR), producing weight loss beyond what GLP-1R agonism alone achieves. Administered once weekly.

EC50 (GLP1R Ki):

28.6 nM

EC50 (GCGR Ki):

17.7 nM

Source:

GlpBio: Mazdutide (CAS 2259884-03-0); Innovent Phase Ib results (eClinicalMedicine 2022).DOI

Clinical Development:

NCT04930343; NCT05592656

References

PubChem:

PubChem

Literature:

GlpBio: Mazdutide (CAS 2259884-03-0); eClinicalMedicine: Innovent Phase Ib results (2022); ClinicalTrials.gov: DREAMS-1 (NCT04930343)

Disclaimer:

Mazdutide is NOT FDA-approved or EMA-approved. It is in Phase 3 clinical trials in China. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

Seller Information

Business Type:
Trader

Main Products:
peptides

Location:
Room 3043, 3rd Floor, Building 15, No. 185 Xinda Road, Wanghailou Street, Hebei District, Tianjin

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$10 million-$25 million

Total Employees:
11-50

Year of Establishment:
2025

Certifications:
.,证书

公司简介

Company Profile
We are a modern, rapidly growing biopharmaceutical company specializing in the production of pharmaceuticals, biologics, and nutraceuticals. We offer internationally leading healthcare products, chemicals, electronics, and mining machinery. Our innovative, full-cycle production facilities fully comply with GMP and ISO standards. We are committed to providing high-quality, affordable, innovative products to prevent disease and support healthier lifestyles. We optimize scientific innovation and production technologies to enable our customers to better serve their consumers. We provide a comprehensive range of services and products for the pharmaceutical and nutraceutical industries, from custom development and production of active ingredients to finished dosage forms. With our scale and resources, we offer our customers one-stop solutions to help people get, feel, and stay well.

Inquiry History

5 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Mazdutide	25 MG	Aug 12, 2026
Nigeria	Mazdutide 10mg	20 PCS	Mar 7, 2026
United States	Mazdutide	30 MG	Jul 15, 2024
United Kingdom	Mazdutide	1 KG	Feb 10, 2026
United States	Mazddultide cas	2 MT	Nov 14, 2025

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