CAS 2805997-46-8 Research Grade Survodutide Synthetic Peptide Lyophilized Powder for Preclinical Lab Research

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Product Introduction

Survodutide, also known as BI‑456906, is a synthetic lipid‑modified 29‑amino‑acid peptide. It acts as dual‑receptor agonist targeting GLP‑1R and GCGR, derived from glucagon backbone with C18 fatty‑acid lipidation modification for extended half‑life research. This compound is widely applied for pre‑clinical laboratory research focusing on incretin signaling, glucose homeostasis and energy‑metabolism related biological pathways. Our Survodutide product is supplied as high‑purity lyophilized white‑to‑off‑white powder. Each batch is verified by HPLC and mass‑spectrometry, complete COA documents can be provided upon buyer’s request.

Mechanism of Action

Survodutide simultaneously binds and activates GLP‑1 receptor and glucagon receptor (GCGR) in laboratory cell models. The C18 fatty‑acid side chain modification improves peptide stability and albumin‑binding property for prolonged signal stimulation. It triggers downstream G‑protein coupled signaling cascades, modulating intracellular cyclic‑AMP related pathways. Under experimental conditions, it regulates multiple metabolic‑associated cellular responses for pre‑clinical mechanism exploration.

Chemical Information

CAS: 2805997‑46‑8

Sequence: His‑{1‑Aminocyclobutanecarboxylic acid}‑Gln‑Gly‑Thr‑Phe‑Thr‑Ser‑Asp‑Tyr‑Ser‑Lys‑Tyr‑Leu‑Asp‑Glu‑Arg‑Ala‑Ala‑Lys‑Asp‑Phe‑Ile‑{Lys(Gly‑Ser‑Gly‑Ser‑Gly‑Gly‑γGlu‑C18 diacid)}‑Trp‑Leu‑Glu‑Ser‑Ala‑NH₂

Molecular Formula: C₁₉₂H₂₈₉N₄₇O₆₁ Molecular

Weight: 4231.63 Da

Appearance: White to off‑white lyophilized powder

Purity: ≥99%

Solubility: Soluble in sterile water and bacteriostatic water

Storage Condition

Lyophilized powder: Store at ‑20℃ under dry sealed environment, avoid direct light. Stable for up to 24‑36 months under proper storage. Reconstituted solution: Store at 2‑8℃, finish laboratory test within 14‑21 days. Avoid repeated freeze‑thaw cycles.

Research Applications

Widely used for life‑science pre‑clinical experiments: dual‑receptor agonist mechanism study, incretin signal‑axis research, glucose metabolism cell model, energy‑expenditure related animal experiments, GPCR‑peptide interaction laboratory research.

Packaging & Logistics

Standard packing: 5mg, 10mg,  sealed vial.

Outer package: Foam box + carton. Transportation: Normal cold chain transportation is optional. Goods will be well sealed to prevent moisture.

Company Profile

We are a high-tech enterprise oriented towards research and development, specializing in the fields of pharmaceutical raw materials, intermediates, peptide components, cosmetic raw materials, and nutritional supplement raw materials. We offer standardized large-scale production services and conduct global wholesale business. Our multiple peptide raw materials possess core physiological effects such as weight loss, muscle building, blood sugar reduction, and anti-aging, are widely applicable to the research and production demands in the pharmaceutical, beauty, and health care sectors.

We adopt strict batch production standards and have sufficient production capacity and stable supply capabilities. All products have been professionally tested by third-party institutions and come with complete test reports and qualification certificates, ensuring stable batch quality and complete traceability. For large-scale orders, we offer competitive wholesale prices. We uphold the core values of integrity, pragmatism, innovation and development, and continuously enhance our technical strength and product quality.

We offer comprehensive high-quality fine raw materials for the pharmaceutical, cosmetic and nutritional product industries. At the same time, we not only support standard batch purchases but also can meet the needs of pilot projects and large-scale industrial production.