Sales Manager：Grace

WhatsApp / WeChat：+8615533197069

Email：Grace@hzzmtrade.com

1. 1.We support large‑scale production and offer customized solutions.
2. 2.Bottle dimensions and milligram filling volumes can be adjusted to meet your requirements.
3. 3.Safe and reliable shipping channels are available.
4. 4.All vials go through vacuum‑sealing treatment.
5. 5.Brand‑new fresh batches are produced every 6‑8 days.

Quality Control: Our products are manufactured in GMP‑certified facilities with full‑process traceability, and supporting documents comply with relevant regulatory standards.

Supply Capacity: A wide range of product specifications are available. We maintain stable lead times and flexible production capacity to adapt to different orders.

Price Benefits: Direct factory‑sourced quotations with discounts for bulk purchases. A well‑functioning stable supply chain caters to diverse market order requirements.

Support Services: Complete sets of documentation are provided, alongside professional technical guidance for formulations.

Melanotan 1 (Afamelanotide) is a 13-amino acid linear synthetic peptide and a potent analog of α-MSH, which effectively promotes eumelanin synthesis by selectively activating the MC1R receptor and upregulating the cAMP-MITF-tyrosinase signaling pathway, inducing UV-independent skin pigmentation and providing photoprotective effects; this product is the active ingredient in the FDA/EMA-approved Scenesse implant for the treatment of phototoxic reactions in erythropoietic protoporphyria (EPP), with Phase III clinical data demonstrating an extension of pain-free sunlight exposure time to 6.0 hours (vs. 0.8 hours in the placebo group) and a nearly 50% reduction in phototoxic reactions, making it widely applicable in photoprotection research, pigmentation regulation, and photodermatosis therapy.

Skin Pigmentation and Photoprotection: Human clinical studies have confirmed that Melanotan 1 significantly increases skin eumelanin content by selectively activating the melanocortin 1 receptor (MC1R), inducing UV-independent skin pigmentation and providing photoprotective effects against UV-induced DNA damage.

Photodermatosis Therapy: As the active ingredient in the FDA and EMA-approved Scenesse® (Afamelanotide 16 mg) implant, Melanotan 1 has been approved for the treatment of phototoxic reactions in erythropoietic protoporphyria (EPP); real-world studies have shown that treatment significantly improves patient quality of life, with 93.3% of patients reporting that therapy changed their outlook on life, and long-term safety has been well established.

Neuroprotection and Cognitive Function: Preclinical studies have demonstrated that Melanotan 1 can cross the blood-brain barrier, improve cognitive function in transgenic mouse models of Alzheimer's disease, and reduce microglial activation, offering new directions for research in neuroprotection and cognitive health.

Inflammation Regulation and Immune Support: Pharmacological studies indicate that Melanotan 1, as a broad-spectrum agonist of melanocortin receptors, can modulate inflammatory responses through activation of MC1R and related receptors, showing potential application value in mechanistic research of inflammatory diseases.

As a synthetic tridecapeptide raw material approved by the FDA and EMA, Melanotan 1 (Afamelanotide) is a structural analog of α-melanocyte-stimulating hormone (α-MSH) and demonstrates extensive application value across multiple cutting-edge research fields. Its core mechanism lies in acting as a melanocortin 1 receptor (MC1-R) agonist, activating this receptor with four times the potency of native α-MSH, thereby stimulating melanocytes to synthesize eumelanin. Through this pathway, Melanotan 1 is widely applied in research on inducing UV-independent skin pigmentation, while also serving as the active ingredient in the approved Scenesse® (16 mg implant) for research on phototoxic reaction prevention and treatment in erythropoietic protoporphyria (EPP), effectively increasing patients' pain-free sunlight exposure time. Building on this foundation, its application scope continues to expand, encompassing repigmentation mechanism research in vitiligo pigmentary disorders, often used in combination with NB-UVB phototherapy to enhance therapeutic efficacy; it also demonstrates potential in photoprotection and repair exploration for photodermatoses such as xeroderma pigmentosum. Furthermore, preclinical studies have extended its neuroprotective effects to the field of experimental Alzheimer's disease, showing that it can cross the blood-brain barrier, improve cognitive function in transgenic mouse models, and reduce microglial activation. This raw material can also serve as a pharmacological tool for melanocortin receptors, widely used in mechanistic research on various dermatological, inflammatory, and neurodegenerative diseases, as well as in the development of multi-target drug lead compounds.

Our company focuses on the R&D and supply of various peptide products. Our main product line includes weight‑loss peptides, anti‑wrinkle peptides, tanning peptides and other peptide raw materials, and we also accept customized peptide product requests. The company has established a complete quality management system with strict quality‑control standards, supported by thoughtful one‑stop customer services. Our experienced team is ready to deliver professional support to fully meet diverse procurement requirements from global clients.

We put customer value at the heart of our business. We stick to high‑product standards while maintaining competitive pricing. Flexible order quantities are supported, and we closely monitor production and lead times to ensure on‑time delivery for every order. Our products are mainly exported to key overseas markets including Europe, the United Kingdom, the United States, Canada and Australia. Thanks to consistent product quality and reliable service systems, we have gained wide recognition and trust from customers worldwide.

We have built mature in‑house cross‑border distribution channels covering the United States, Canada, the United Kingdom, Spain, Poland, the Netherlands, Germany, Russia, Kazakhstan and other regions. Door‑to‑door one‑stop delivery is available with streamlined customs clearance, eliminating customs‑related issues and enabling hassle‑free receipt of goods for customers.

Strict internal controls are implemented across the whole workflow, from raw‑material selection and production to logistics delivery. Only high‑purity, premium‑grade raw materials are adopted. Guided by the core philosophy of “survive by quality, grow by reputation”, we supervise every production procedure to guarantee stable product quality from the source.

We possess distinctive product and service strengths: safe and efficient production technology balances consistent quality and fast turnaround. Sample testing services are offered prior to formal bulk orders for customers to verify product performance. With years of experience serving overseas markets, we provide cost‑effective goods together with comprehensive after‑sales support to resolve all kinds of cooperation‑related issues efficiently. We aim for full customer satisfaction and strive to build a trustworthy international brand.

Going forward, we will keep focusing on the R&D and manufacturing of high‑quality products, optimize pricing structures, improve professional technical and commercial support, and build a highly efficient team. Upholding the principle of integrity and win‑win partnership, we will continuously upgrade after‑sales services to maximize value for every partner.