high purity Semax ACTH (4-7), Pro-Gly-Pro-/Nootropic Peptide

Description

Semax is a synthetic heptapeptide with the amino acid sequence Met-Glu-His-Phe-Pro-Gly-Pro, molecular formula C₃₇H₅₁N₉O₁₀S, molecular weight approximately 813.9, and CAS Number 80714-61-0. Derived from an active fragment of adrenocorticotropic hormone (ACTH), it has enhanced stability and bioactivity through C-terminal structural modifications and is currently one of the most extensively studied peptides in the field of neuroscience. This product is a high-purity (≥99%, as determined by HPLC) lyophilized powder that is stable, easy to store, and convenient for experimental preparation, making it suitable for a wide range of scientific research experiments.

Key Effects

The core value of Semax in scientific research lies in its modulatory effects on the central nervous system. As a stabilized analog of the active fragment of ACTH, it has been observed in numerous animal studies to influence pathways related to learning and memory and is closely associated with the regulation of neurotrophic factors (such as BDNF) in the brain. Additionally, its modified molecular structure confers strong metabolic stability, allowing it to maintain its effects for an extended period during experiments—a key reason for its widespread use in neuroscience research.

1. Cognitive Function Research: Observed in animal studies to enhance learning and memory behaviors, it is a popular tool peptide in the field of cognitive research.

2. Neurotrophic Regulation: Studies show that it can regulate the expression of brain-derived neurotrophic factor (BDNF), which is relevant to research on neuronal growth and survival.

3. Neuroprotective Effects: A certain degree of neuroprotective effect has been observed in animal models of cerebral ischemia and nerve injury.

4. High Metabolic Stability: C-terminal structural modifications enhance its resistance to enzymatic degradation, resulting in a longer duration of action, making it suitable for studies involving long-term observation.

Applications

Semax is currently used primarily in scientific research related to neuroscience and brain function, covering various aspects ranging from molecular mechanisms to animal behavioral experiments. It is a commonly used tool compound in the fields of cognitive function, neuroprotection, and neurotrophic factor research, and also serves as a reference molecule for the development of related drugs.

1. Cognitive, Learning, and Memory Research: Used in behavioral and molecular experiments investigating the mechanisms of learning and memory, as well as the regulation of cognitive function.

2. Neuroprotection Research: Used to explore protective mechanisms in models of cerebral ischemia, brain injury, and other conditions.

3. Neurotrophic Factor Research: Used to study the expression and signaling pathways of neurotrophic factors such as BDNF.

4. Animal Behavioral Experiments: Suitable for drug administration and behavioral observation experiments in models such as mice and rats.

5. Standard Reference Material: Can serve as a standard reference material for the development of relevant peptide detection methods and quality analysis.