Isovitexin 2''-O-β-glucoside 95% Purity CAS 60767-80-8 Flavone C-Glycoside for Antioxidant and UV-Protection Research Reagent Grade

• Product Overview

  Isovitexin 2''-O-β-glucoside, also known as Meloside A, is a naturally occurring flavone C-glycoside compound first isolated from barley (Hordeum vulgare) and also found in cucumber leaves (Cucumis sativus) and various other plant sources. It belongs to the class of flavonoid C-glycosides, where the sugar moiety is attached directly to the flavone core via a carbon-carbon bond, providing enhanced stability compared to O-glycosides. This product is a research-grade reagent with a purity of ≥95% as determined by HPLC analysis, appearing as a yellow to off-white powder.

  Chemical Properties

  • Molecular Formula: C₂₇H₃₀O₁₅

  • Molecular Weight: 594.52 g/mol

  • Synonyms: Meloside A; Isovitexin 2''-O-glucoside; 2''-O-β-D-Glucopyranosylisovitexin

  • Solubility: Soluble in DMSO (90 mg/mL), methanol, ethanol

  Natural Sources and Biosynthesis

  Isovitexin 2''-O-β-glucoside is a phenylpropanoid compound that accumulates in plants as a protective metabolite. In barley, phenylpropanoids have been described as having protective properties against excess UV-B radiation and have been linked to resistance to pathogens. The compound is structurally related to other flavone C-glycosides and is formed by the glucosylation of isovitexin at the 2''-position.

  Biological Activities

  • Antioxidant Activity: Meloside A exhibits potent antioxidant properties, effectively scavenging free radicals and protecting cells from oxidative stress.

  • UV-Protective Properties: As a phenylpropanoid, it contributes to plant defense against UV-B radiation, making it valuable for photoprotection research.

  • Pathogen Resistance: Linked to resistance to pathogens in barley, suggesting potential antimicrobial applications.

  • Pharmaceutical Research: Widely used in research in the fields of pharmaceuticals, cosmetics, and health products.

  Extraction and Purification Process

  The compound is typically extracted from plant materials using aqueous methanol or ethanol, followed by chromatographic separation and purification using techniques such as macroporous resin chromatography and preparative HPLC.

  Quality Specifications

  • Purity: ≥95.0% (determined by HPLC area normalization)

  • Appearance: Yellow to off-white powder

  • Identification: Conforms to structure by NMR and Mass Spectrometry

  • Loss on Drying: ≤0.5%

  • Residue on Ignition: ≤0.1%

  • Heavy Metals: ≤10 ppm

  • Each batch is accompanied by a comprehensive Certificate of Analysis (COA).

  Packaging & Storage

  • Packaging: Available in 5mg, 10mg, 20mg, 50mg amber glass vials for research purposes. Larger quantities are available upon request.

  • Storage: Store powder in a tightly sealed container, protected from light, at 4°C for up to 24 months, or at -20°C for extended storage. For stock solutions, store as aliquots at -20°C for up to 1 month. Allow product to equilibrate to room temperature for at least 1 hour before opening to avoid moisture condensation.

  • Shelf Life: 24 months when stored under recommended conditions.

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.