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Food Grade L-Serine Amino Acid Powder for Nutritional Supplements and Functional Foods

Name: Food Grade L-Serine Amino Acid Powder for Nutritional Supplements and Functional Foods
Brand: ONERBIO
SKU: pr2609101771
Price: 4 USD
Availability: InStock

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CAS No.:

56-45-1

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

ONERBIO

Packaging:

25kg/drum

Sample Available:

Yes

Price valid (until):

2026-10-10

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Wuhan Oner Biotech Co.,Ltd.

Company Type:

Distributor

Location:

China

Payment Terms:

TT against copy of documents

Average Lead Time:

5 days

Qualification:

Main Products:

Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

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Product Details
Seller Information
Inquiry History

Description

Product Name: L-Serine
CAS Number: 56-45-1
Molecular Formula: C₃H₇NO₃
Molecular Weight: 105.09 g/mol
Appearance: White to off-white crystalline powder

L-Serine is a chiral, proteinogenic amino acid with a polar, uncharged side chain containing a hydroxyl group. It appears as a white to off-white crystalline powder and is freely soluble in water, slightly soluble in lower alcohols and other polar solvents, and practically insoluble in nonpolar media. The compound is optically active and exists predominantly in the L configuration in natural systems. Its hydroxyl-bearing side chain supports hydrogen bonding, metal coordination, and post-translational modification, especially phosphorylation. Functionally, L-Serine serves as a building block for protein synthesis and as a precursor in the formation of glycine, cysteine, tryptophan, sphingolipids, purines, and other metabolites. It participates in one-carbon metabolism and contributes to nucleotide and lipid biosynthesis. It is widely used in cell culture media, biopharmaceutical formulations, parenteral nutrition, and biochemical research. In cosmetic and personal care products, it is incorporated for its moisturizing and skin-conditioning properties. It is also employed as a buffering agent and chiral intermediate in organic synthesis. L-Serine should be stored in a cool, dry, well-ventilated place, protected from moisture, heat, and strong oxidizing agents. It is generally considered safe under appropriate handling, but standard laboratory precautions are recommended.

ITEMS	STANDARDS		RESULTS
Description	White to almost white powder		White powder
UV absorbance ratio	A250/A260 A280/A260	0.41-0.49 2.03-2.71	0.45 2.14
PH	2.0-4.0		2.68
Loss on drying	≤5.0%		2.64%
Assay (UV)	≥98.0%		99.17%
Transmittance	≥98.5%		99.1%
Heavy metals	≤10ppm		＜10ppm
Purity (HPLC)	≥98.0%		99.6%
Conclusion	It complies to the standard

For regulatory compliance (e.g., USP, EP, JP), raw material Vidarabine must meet several rigorous standards:

Assay (by HPLC): 98.0% – 102.0% on an anhydrous basis.
Related Substances: Limits for specific impurities, notably Ara-Hx (NMT 2.0%), as well as any unspecified individual impurity (NMT 0.1%) and total impurities (NMT 2.0%).
Residual Solvents: Must comply with ICH Q3C guidelines (Class 1 and 2 solvents limited or absent).
Heavy Metals: NMT 20 ppm (typically lower for injectable grades).
Water Content (Karl Fischer): NMT 6.0% (the material is hygroscopic to a degree).
Microbial Limits: Total aerobic microbial count (TAMC) ≤ 1000 CFU/g, absence of S. aureus, P. aeruginosa, and Candida albicans.

As a high-purity pharmaceutical intermediate, L-Tyrosine Ethyl Ester Hydrochloride is predominantly utilized in the chemical synthesis of bioactive peptides, dopamine analogs, and melanin precursors. Its excellent solubility profile makes it an ideal chiral building block for asymmetric synthesis and a critical substrate in enzymatic reactions. Available in purity grades of ≥98% (HPLC), it meets stringent requirements for R&D and cGMP manufacturing processes. Reliable supply ensures batch-to-batch consistency for long-term project scalability.

Vidarabine is classified as a potential reproductive hazard and an irritant. Safety Data Sheets (SDS) mandate the following:

Hazard Statements (H360): May damage fertility or the unborn child (Category 1B).
Precautionary Measures: Use fume hoods and wear impermeable gloves (e.g., nitrile), lab coats, and safety goggles. Avoid generating airborne dust.
First Aid: In case of skin contact, wash immediately with copious soap and water. If inhaled, move to fresh air.
Storage: Store in tightly sealed, light-resistant containers at 2°C to 8°C (refrigerated) for long-term stability. Avoid freezing.

While superseded by newer nucleoside analogs (Acyclovir, Ganciclovir) for systemic use due to better bioavailability and lower toxicity, Vidarabine retains niche value. Its primary current application is ophthalmic ointment (3%) . Pharmacokinetically, the raw material has poor oral bioavailability (<10%) and is rapidly deaminated in the gastrointestinal tract, necessitating parenteral or topical administration.

Vidarabine API is a well-characterized, stable crystalline nucleoside analog. While its systemic use has declined, it remains a critical raw material for topical antiviral ophthalmic preparations, particularly where resistance to other agents occurs. Manufacturers must strictly control impurities (especially Ara-Hx) and water content to ensure final drug product efficacy.

ECHEMI Editorial Reference

L-Serine, one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
Solid
L-serine is the L-enantiomer of serine. It has a role as a human metabolite, an algal metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a serine family amino acid, a proteinogenic amino acid, a L-alpha-amino acid and a serine. It is a conjugate base of a L-serinium. It is a conjugate acid of a L-serinate. It is an enantiomer of a D-serine. It is a tautomer of a L-serine zwitterion.|A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.|Serine is a non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for the metabolism of fats, fatty acids, and cell membranes; muscle growth; and a healthy immune system. It also plays a major role in pyrimidine, purine, creatine, and porphyrin biosynthetic pathways. Serine is also found at the active site of the serine protease enzyme class that includes trypsin and chymotrypsin. (NCI04)|A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.

Certificates

Basic Info

Product Name:

L-Serine

Other Name:

L-Serine;Serine,L-;(S)-α-Amino-β-hydroxypropionic acid;β-Hydroxy-L-alanine;Serine;L-(-)-Serine;Propanoic acid,2-amino-3-hydroxy-,(S)-;(S)-2-Amino-3-hydroxypropanoic acid;(S)-Serine;L-3-Hydroxy-2-aminopropionic acid;(-)-Serine;L-Alanine,3-hydroxy-;L-Ser;(2S)-2-Amino-3-hydroxypropanoic acid;(2S)-2-Azaniumyl-3-hydroxypropanoate;2: PN: WO2020113403 TABLE: L1 claimed sequence;4: PN: WO2020191289 PAGE: 118 claimed sequence;10: PN: WO2021055880 SEQID: 11 claimed protein;6898-95-9;154605-73-9

CAS No.:

56-45-1

Molecular Formula:

C3H7NO3

InChIKeys:

InChIKey=MTCFGRXMJLQNBG-REOHCLBHSA-N

Molecular Weight:

105.09300

Exact Mass:

105.09

EC Number:

200-274-3

UNII:

452VLY9402

NSC Number:

760115

NCI Thesaurus Code:

C29613

Color/Form:

HEXAGONAL PLATES OR PRISMS|COLORLESS CRYSTALS

HScode:

29225000

Categories:

Nutrition Supplements

Characteristics

PSA:

83.55000

XLogP3:

-3.1

Appearance:

Solid

Density:

1.6 g/cm³ @ Temp: 22 °C

Melting Point:

228 °C (decomp)

Boiling Point:

394.8ºC at 760mmHg

Flash Point:

192.6ºC

Refractive Index:

1.519

Water Solubility:

H2O: 425.0 mg/mL;425.0 mg/mL

Storage Conditions:

Store at 0-5ºC

Specific rotation:

SPECIFIC OPTICAL ROTATION: -6.83 DEG @ 20 °C/D (1.5 G IN 15 G AQ SOLN); +14.45 DEG @ 25 °C/D (C= 0.5 G IN 5.6 NORMAL HCL)

Taste:

SWEETISH TASTE, INSIPID AFTERTASTE

PKA:

2.21(at 25 °C)

Dissociation Constants:

2.21 (at 25 °C)|pKa = 2.21; pKb = 9.15

Collision Cross Section:

136.66 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|136.2 Å² [M-H]-

Experimental Properties:

DECOMPOSES @ 228 °C; SUBLIMES @ 150 °C IN HIGH VACUUM (10-4 MM HG); MOLECULAR ROTATION IN 5 N HCL +15.0 DEG|OPTICALLY ACTIVE

See More L-Serine Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More L-Serine Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

Location:
Changqing 5th Road, Jianghan District

Payment Terms:
TT against copy of documents

Average lead Time:
5 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
5-10

Year of Establishment:
2020

Wuhan Oner Biotech Co.,Ltd. located in the popular city of Wuhan, specilize in producing and developing pharmaceutical & its intermediates, Cosmetics Raw Material and Intermediate, food additive, Plant extracts,and in distributing the products of our own company. We serves our clients by supplying high-quality.These products are manufactured in ISO 9001 certified plants and have continuously been passing quality inspection by CIQ (China Entry & Exit Inspection and Quarantine Bureau),100% pass rate. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , the products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

Inquiry History

11 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	L-Serine	50 KG	Sep 17, 2026
India	L-Serine	25354 KG	Jul 8, 2026
United States	L-Serine	1.00 MT	Jul 2, 2026
United States	L-Serine	1 MT	Jun 29, 2026
Greece	SERINE (Ser, S)	700.00 KG	Sep 24, 2025
India	L-Serine	1 KG	Aug 14, 2025
Germany	Potassium Sorbate	50.00 KG	May 8, 2025
Germany	L-carnitine	25.00 KG	May 8, 2025
India	L-Serine	1 MT	Apr 23, 2025
India	L-serine	25.00 KG	Mar 13, 2025
India	L-serine	3.00 KG	Dec 19, 2024

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Food Grade L-Serine Amino Acid Powder for Nutritional Supplements and Functional Foods

Product Details

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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