Acetyl Tetrapeptide-5, Eyeseryl/anti-glycation, anti-edema/de-puffing, dark circle reduction, anti-wrinkle & firming, moisturizing, skin conditioning

Description

Acetyl Tetrapeptide-5 (Chinese name: Acetyl Tetrapeptide-5, also known as Eyeseryl) is a synthetic tetrapeptide cosmetic active ingredient with CAS No. 820959-17-9, molecular formula C₂₀H₂₈N₈O₇ and molecular weight of 492.5. It was originally developed by Lipotec, a Spanish company. As a functional peptide specially designed for skin problems around the eyes, it is widely used in eye care formulations worldwide. This product is a high-purity (≥98%, tested by HPLC) white powder with good water solubility and strong compatibility, which is easy to be incorporated into various skincare formulations.

Key Effects

The core function of Acetyl Tetrapeptide-5 focuses on "reducing puffiness and firming" the skin around the eyes. By inhibiting the activity of angiotensin-converting enzyme (ACE-1), it helps improve the local microcirculation around the eyes and reduce interstitial fluid retention, thereby alleviating the appearance of eye bags and puffiness caused by accumulated moisture. Meanwhile, it can help enhance the firmness and smoothness of periorbital skin, making it one of the peptide ingredients with relatively sufficient evidence for eye area concerns at present.

Specifically, its functions demonstrated in skincare formulations include:
Reducing periorbital puffiness: Helps regulate fluid circulation in eye tissues and relieve puffiness resulting from fluid retention.
Diminishing the appearance of eye bags: For sagging and bulging eye bags around the eyes, long-term use can help improve their visual appearance.
Fading dark circles: By improving local microcirculation, it helps lessen dullness and dark circles triggered by poor circulation.
Firming periorbital skin: Helps boost the firmness and elasticity of delicate skin around the eyes for a smoother-looking eye area.
Mild and skin-friendly properties: As a small-molecule peptide with good water solubility, it meets the formulation requirements for sensitive periorbital skin.

Applications

Acetyl Tetrapeptide-5 is a classic peptide raw material in the eye care category. It is mainly used in the formula development of various eye creams, eye serums, eye masks and other products, and can also be extended for facial firming and anti-aging products. With the popularity of the peptide skincare concept, it has become a commonly used active ingredient in mid-to-high-end eye care formulas, boasting high market recognition and stable repurchase demand.

Specific application scenarios include:
Eye care products: Used in eye creams, eye serums, eye masks and other products, targeting the improvement of eye bags, puffiness and dark circles.
Firming and anti-aging formulas: Added to facial firming and anti-aging serums and creams to synergistically enhance skin tightness.
Cosmetic formula research and development: Applied as a peptide active ingredient in formula development and efficacy verification of new skincare products.
Compound peptide products: Can be compounded with other skincare peptides such as Acetyl Hexapeptide-8 and Palmitoyl Pentapeptide-4 to form multi-target peptide formulas.
Raw material packaging and supply: Provide raw material sub-packaging and customized services for skincare manufacturers, brands and laboratories.