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(-)-Carnitine

1-Propanaminium,3-carboxy-2-hydroxy-N,N,N-trimethyl-,inner salt,(2R)-;Ammonium,(3-carboxy-2-hydroxypropyl)trimethyl-,hydroxide,inner salt,L-;1-Propanaminium,3-carboxy-2-hydroxy-N,N,N-trimethyl-,hydroxide,inner salt,(R)-;(-)-Carnitine;Carnitine,(-)-;l-Carnitine;Vitamin BT;L-(-)-Carnitine;Carnitine;L-Carnitine;(-)-L-Carnitine;Levocarnitine;(R)-Carnitine;1-Propanaminium,3-carboxy-2-hydroxy-N,N,N-trimethyl-,inner salt,(R)-;ST 198;Carniking 50;Carnitene;Carniking;Carnitor;Carnilean;Coaxel;Carnipass;Carnipass 20;L-Carnipure;Natrulon RC;Carnivit;Carnil;Aminocarnifarm;(3R)-3-Hydroxy-4-(trimethylazaniumyl)butanoate;101512-81-6;4209-27-2;7634-98-2

541-15-1

C7H15NO3

InChIKey=PHIQHXFUZVPYII-ZCFIWIBFSA-N

161.199

161.105194

208-768-0

0G389FZZ9M

759132|741806

DTXSID4023208

C26657

White, crystalline, hygroscopic powder

A16AA01|A - Alimentary tract and metabolism

29239000

Bulk Drug Intermediates

60.36000

-0.2

Solid

0.64 g/cm3

196-198 °C

-32 ° (C=1, H2O)

2500 g/L (20 ºC)

2-8°C

LD50 orally in Rabbit: > 5000 mg/kg

The specific optical rotation is between -29 and -32

3.8None

133.1 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|130 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|132.9 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|132.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Hydroxyl radical reaction rate constant = 2.7X10-11 cu cm/molecule-sec at 25 °C (est)

Mitochondria-targeted tetrapeptide (Szeto-Schiller peptide)

FDA-approved (Forzinity) — Accelerated Approval 2025

A cell-permeable, synthetic tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) that selectively concentrates in the inner mitochondrial membrane and reversibly binds to cardiolipin, a phospholipid essential for electron transport chain (ETC) function. By stabilizing cardiolipin, SS-31 restores mitochondrial bioenergetics, reduces cytochrome c peroxidase activity, and prevents oxidative damage in cells with impaired mitochondrial function.

SS-31 does not act via traditional receptor agonism. It binds cardiolipin with high selectivity in the inner mitochondrial membrane. Functional EC₅₀ values are context-dependent (cell type, stress model). Key electrophysiology studies report mitochondrial membrane potential restoration at nanomolar concentrations.

Szeto HH, et al. AAPS J. 2006;8(2):E277-E283. Birk AV, et al. J Am Soc Nephrol. 2014;25(6):1157-1169.DOI

NCT03098797; NCT02814097; NCT02976038; NCT03354065

Forzinity (approved 2025-09-19)

CHEMBL3833370

DB11981

D10925

PubChem

FDA: Forzinity (NDA 215244) — Accelerated Approval 2025; Genetics in Medicine: TAZPOWER Phase 2/3 results (Thompson et al. 2020); Drugs: Elamipretide First Approval (Springer 2025)

Elamipretide (Forzinity) is FDA-approved under accelerated approval for Barth syndrome. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.