Moclobemide/reversible MAO-A inhibitor (RIMA), monoamine/5-HT modulation, antidepressant direction

Description

This product is Moclobemide (chemical name: 4-chloro-N-(2-morpholinoethyl)benzamide) with CAS No. 71320-77-9. It is a synthetic small-molecule pharmaceutical ingredient and belongs to the class of antidepressants widely used in clinical practice. The molecular formula of the product is C₁₃H₁₇ClN₂O₂, and its molecular weight is approximately 268.74. It normally appears as white to off-white crystalline powder with a purity of over 98% (tested by HPLC). The pharmaceutical-grade product complies with relevant pharmacopoeia standards. As a mature commercial pharmaceutical raw material, this product can be supplied in different specifications such as pharmaceutical grade and reagent grade according to application purposes. It is mainly provided to pharmaceutical enterprises, formulation manufacturers and scientific research institutions, and is one of the antidepressant raw materials with large circulation in domestic and overseas markets. The product shall be stored in a sealed, light-proof, cool and dry place.

Key Effects

Depression is associated with low levels of certain "happy messengers" in the brain, namely neurotransmitters. The human body produces an enzyme called monoamine oxidase, which breaks down these neurotransmitters and reduces their concentrations. Moclobemide works by moderately inhibiting the activity of this enzyme, reducing the breakdown of neurotransmitters and maintaining adequate levels of brain substances involved in mood regulation, thereby helping to relieve depressive symptoms. Compared with traditional drugs of the same class, it exerts reversible and more selective inhibition with higher safety and fewer dietary restrictions, so it is widely used as a first-line therapeutic agent for depression in clinical practice.

Its specific functions can be summarized as follows:
Regulate mood-related substances: Inhibit monoamine oxidase activity to help maintain the levels of mood-regulating substances in the brain;
Alleviate depressive symptoms: Applied in the treatment of depression to relieve symptoms such as low mood and loss of interest;
Treat social anxiety: It can also be used clinically to improve social anxiety disorder;
Higher safety: It has reversible inhibitory effects and good selectivity, with fewer adverse reactions than traditional drugs of the same class;
Role as a research tool: Serves as a standard compound of monoamine oxidase inhibitors for neuropsychopharmacological research.

Applications

This product is classified as a pharmaceutical API, mainly targeting the production and research & development of neuropsychiatric drugs, with clear application directions and a solid clinical foundation.

Its main application fields are summarized as follows:
Manufacture of antidepressants: Serves as the active pharmaceutical ingredient for oral preparations (such as tablets) used to treat depression;
Treatment of anxiety disorders: Used as the raw material for preparations related to social anxiety disorder;
Research and development of psychotropic drugs: Acts as a lead compound or reference standard for the research, development and evaluation of antidepressants;
Quality research and testing: Used as a reference standard for the assay and impurity study of APIs and preparations;
Supply of research reagents: Provided to universities, research institutes and pharmaceutical laboratories as experimental materials for neuropharmacological research;
Export trade and raw material supply: Supplied as pharmaceutical raw materials to pharmaceutical factories, preparation manufacturers, R&D institutions and traders, with specifications available upon customer requests.