High Purity Candesartan cilexetil CAS 145040-37-5 >98% Solid For Laboratory Research
1 Inquiries
145040-37-5
Chemicals
99%
Qingdao
Guozhao
25kg/drum
Yes
2026-11-09
CHEMICALS
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceWhite SolidCandesartan cilexetil is a kind of prodrug being hydrolyzed to candesartan during absorption from the gastrointestinal tract. It appears as a white or off-white powder with a molecular weight of 610.67. It is soluble in methanol but insoluble in water. It is a kind of selective AT1 subtype angiotensin II receptor antagonist, mainly used for the treatment of hypertension and heart failure. Candesartan cilexetil takes effects through selectively blocking the binding of angiotensin II t
Candesartan cilexetil is a member of biphenyls.|Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease.Basic Info-
Product Name:
Candesartan cilexetil
Other Name:1H-Benzimidazole-7-carboxylic acid,2-ethoxy-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-,1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester;1H-Benzimidazole-7-carboxylic acid,2-ethoxy-1-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-,1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester,(±)-;1H-Benzimidazole-7-carboxylic acid,2-ethoxy-1-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-,1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester;TCV 116;(±)-1-Hydroxyethyl 2-ethoxy-1-[p-(o-1H-tetrazol-5-ylphenyl)l]-7-benzimidazolecarboxylate,cyclohexyl carbonate (ester);Candesartan cilexetil;Atacand;TCY 116;Blopress;2-Ethoxy-1-[(2′-(1H-tetrazol-5-yl)-1,1′-biphenyl-4-yl)methyl]-7-benzimidazolecarboxylic acid 1-(cyclohexyloxycarbonyloxy)ethyl ester;1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl 2-ethoxy-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate;1-Cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate;1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl 2-ethoxy-1-([4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl)-1H-1,3-benzodiazole-7-carboxylate;139481-74-6;198077-85-9;2050948-41-7
CAS No.:145040-37-5
Molecular Formula:C33H34N6O6
InChIKeys:InChIKey=GHOSNRCGJFBJIB-UHFFFAOYSA-N
Molecular Weight:610.66
Exact Mass:610.66
EC Number:1592732-453-0
NSC Number:758697
DSSTox ID:DTXSID5020239
HScode:29339953
Categories:
Characteristics-
PSA:
143
XLogP3:7
Appearance:white to beige
Density:1.37±0.1 g/cm3(Predicted)
Melting Point:163 °C (decomp)
Boiling Point:843.3±75.0 °C(Predicted)
Flash Point:463.8±37.1 °C
Refractive Index:1.667
Water Solubility:DMSO: ≥15mg/mL
Storage Conditions:-20°C Freezer
Collision Cross Section:241.5 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Distributor
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Main Products:
CHEMICALS
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Location:
No. 109, Chailu Street, Qingnian Park Subdistrict, Huaian District, Jinan City, Shandong Province 280
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Year of Establishment:
2026
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Vietnam
Candesartan cilexetil
5 KG May 16, 2026 Post an enquiry for this product
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