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Entecavir hydrate Entecavir Monohydrate, Entecavir CAS No: 209216-23-9

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Unit Price:

$35-43/KG FOB

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CAS No.:

209216-23-9

Grade:

Industrial Grade

Content:

99%

Port:

Qingdao

Brand:

Packaging:

25 kg pp drum

Sample Available:

Yes

Price valid (until):

2026-10-29

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Shandong Guozhao Import and Export Co., Ltd.

Company Type:

Distributor

Location:

China

Qualification:

Main Products:

CHEMICALS

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Product Description
Seller Information
Inquiry History

Description

Entecavir Monohydrate CAS No: 209216-23-9

Product Description

Entecavir monohydrate is a new type of cyclovaleryl guanosine anti hepatitis B virus drug. Its pharmacological action is similar to that of Entecavir. It is clinically applicable to the treatment of chronic adult hepatitis B with active virus replication, continuous elevation of serum aminotransferase ALT, or liver histology showing active lesions.
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Test items	Acceptance criteria	Result
Description	White to off-white powder	White powder
Identification	1)The IR absorption spectrum of the sample must be concordant with entecavir 2) RT of the sample should match that of standardin assay preparation	Conform Conform
Water	5.8%-6.5%	6.2%
Optical rotation	+24.0°-+28.0°(DMF:MeOH=1:1 c=1%)	+26.6°
Residue on ignition	≤0.1%	0.09%
Heavy metals	≤20ppm	<20ppm
Related Substances	Total impurities ≤0.3% Any individual impurity ≤0.1%	0.12 0.02%
Assay(HPLC)	98.0% -102.0%( on anhydrous basis)	100.0%
Residual solvents	dic-hloromethane≤600ppm meth-anol≤3000ppm ethyl-acetate≤5000ppm tol-uene≤890ppm	not detected not detected not detected not detected
Conclusion: conform

Application

Entecavir, a nucleoside analogue of guanine, has an inhibitory effect on hepatitis B virus (HBV) polymerase. It can be converted into active triphosphate through phosphorylation. The half-life of triphosphate in cells is 15 hours. The natural substrate competes with the deoxyguanosine triphosphate of HBV polymerase, and entecavir triphosphate can inhibit all three activities of viral (reverse transcriptase):

(1) HBV polymerase promoter;
(2) Before the formation of reverse transcriptional negative chain synthesis of genomic mRNA;
(3) HBV DNA is a strand.

Can be applied to:
Treat hepatitis B infection. Helps prevent hepatitis B virus from multiplying and infecting new hepatocytes. Entecavir is also used to treat chronic hepatitis B infected with HIV/AIDS in adults.
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Free Samples

Free of charge.
We are ready to provide samples for you test, normally 20g/bag.

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Packaging & Shipping

Standard export packing (25kg per bag).

As per customer's request

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Company Profile

Shandong Guozhao Import and Export Co., Ltd is an emerging supplier of high quality ingredients which based in Shandong province, China.

Guozhao was established by group of experts who have more than ten years experiences in pharmaceutical and food ingredients industries. with our deep knowledge and diligence, together with our associated plants, we would like to provide one-stop sourcing solutions for customers, to save your time and secure your purchasing.

FAQ

1. What are the suitable populations for Entecavir monohydrate ?
Entecavir monohydrate has obvious auxiliary effect on the treatment of chronic hepatitis B, and is mainly suitable for people with chronic hepatitis B.

2.Can I get some sample for test?

Sure, we can supply samples free for your test. Normally 10g to 20g is enough.

3.Is NMN suitable for long-distance ocean transport?
Yes. We understand your concern. The Entecavir monohydrate will be packed in 1kg Aluminum foil bag, and 25KG carton box, then tray wrapped film, which is suitable for long-distance land and sea transportation. When shipping, we will apply for positions below the water level.

4.How can you guarantee the quality?
We have regular factory inspection to view the production status. And compare all qualified batches to select the best one for our customer before delivery.

5.When can you deliver goods if we confirm the order?
We will arrange the latest production batch for you, within seven days.

Dear friends, now contact us to get more benefit!

About the Supplier

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Company Profile

About Us

We, founded in 2017 based in China, is committed to providing products and services that are beneficial to human life and health, and we aspire to provide one-stop sourcing solutions for customers at every step.

We specialize in offering a variety of raw ingredients, such as food sweeteners, nutrition enhancers, also Pharmaceutical raw materials.

Sweeteners: Sucralose, Neotame, Stevia extract, Erythritol, Monk fruit extract;

Nutrition enhancers: Creatine monohydrate, Alpha Lipoic Acid, Coenzyme Q10, L-Glutathione reduced;

Pharmaceutical Raw Materials: Rocuronium bromide, PVP K23, PVP K30, etc.

Our Team

The company was established by a group of experts who have education background of world-class universities, and more than twenty years of industry-related experiences, and committed to the development of products that are beneficial to our clients.

There is a also a group of energetic young people who are willing to learn, brave in innovation, and provide an experience that better meets customer needs.

We care about employee growth and provide various opportunities to help them grow.

Our partners

Base everything and anything upon customers' interests and provide quality and value-added services from the date of establishment, SCM Pioneering has a rapid development, with customers in over 30 Countries up to now.

Company philosophy

We care about life, health, and pay attention to innovation.

We regard staff growth, focus customer, and open to the change.

About Our Factory & Business Background

Our Production Capability & Technical Expertise

Our Industry Experience & Global Business Record

FAQ

ECHEMI Editorial Reference

Entecavir monohydrate (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.

Basic Info

Product Name:

Entecavir monohydrate

Other Name:

6H-Purin-6-one,2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-,hydrate (1:1);6H-Purin-6-one,2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-,monohydrate;Entecavir monohydrate

CAS No.:

209216-23-9

Molecular Formula:

C12H15N5O3.H2O

InChIKeys:

InChIKey=YXPVEXCTPGULBZ-WQYNNSOESA-N

Molecular Weight:

295.29448

Exact Mass:

295.128052

EC Number:

606-668-5

HScode:

2933990090

Categories:

Synthetic Anti-infective Drugs

Characteristics

PSA:

127

XLogP3:

-0.31090

Appearance:

White crystalline powder

Density:

1.81

Melting Point:

>220°

Boiling Point:

734.2°C at 760 mmHg

Flash Point:

353.8ºC

Vapor Pressure:

2.15E-18mmHg at 25°C

See More Entecavir monohydrate Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Carcinogenicity, Category 2

Reproductive toxicity, Category 2

Specific target organ toxicity â repeated exposure, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H351 Suspected of causing cancer H361 Suspected of damaging fertility or the unborn child H372 Causes damage to organs through prolonged or repeated exposure
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P318 IF exposed or concerned, get medical advice. P319 Get medical help if you feel unwell.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Entecavir monohydrate Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
CHEMICALS

Location:
No. 109, Chailu Street, Qingnian Park Subdistrict, Huaian District, Jinan City, Shandong Province 280

Year of Establishment:
2026

Shandong Guozhao Import and Export Co., Ltd., located at No. 280, Chalu Street, Qingnian Park Subdistrict, Huaiyin District, Jinan City, Shandong Province, primarily engages in import and export of goods; sales of chemical products (excluding licensed chemical products); sales of specialty chemical products (excluding hazardous chemicals); sales of plastic products; sales of metal products; sales of building materials; sales of architectural decoration materials; sales of daily-use chemical products; sales of food additives; sales of feed additives; sales of fertilizers; sales of batteries; and general cargo warehousing services (excluding items requiring licensing or approval, such as hazardous chemicals).

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Pakistan	Entecavir Monohydrate	500 G	Apr 26, 2024

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Entecavir hydrate Entecavir Monohydrate, Entecavir CAS No: 209216-23-9

Product Description

Seller Information

Inquiry History

About the Supplier

Company Profile

About Our Factory & Business Background

Our Production Capability & Technical Expertise

Our Industry Experience & Global Business Record

FAQ

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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