Special Deal 4-Aminophenol Raw Material for Pharmaceutical Intermediate and Fine Chemical Production

4-Aminophenol

Phenol,4-amino-;Phenol,p-amino-;4-Aminophenol;C.I. 76550;Activol;p-Aminophenol;Azol;BASF Ursol P Base;Benzofur P;Certinal;Citol;C.I. Oxidation Base 6;Durafur Brown RB;Fouramine P;Fourrine 84;Fourrine P Base;Furro P base;p-Hydroxyaniline;4-Hydroxyaniline;Nako Brown R;Paranol;Pelagol P Base;Pelagol Grey P Base;Renal AC;Rodinal;Tertral P Base;Unal;Ursol P;Ursol P Base;Zoba Brown P Base;p-Hydroxyphenylamine;4-Amino-1-hydroxybenzene;1-Amino-4-hydroxybenzene;4-Hydroxybenzenamine;4-Hydroxyphenylamine;4-Hydroxy-1-aminobenzene;NSC 1545;A 0384;52985-09-8;1309774-68-2

123-30-8

C6H7NO

InChIKey=PLIKAWJENQZMHA-UHFFFAOYSA-N

109.13

109.13

385836

204-616-2

R7P8FRP05V

1545

2512

DTXSID3024499

Orthorhombic plates from water|White plates from water|Colorless crystals|White or reddish yellow crystals turn violet on exposure to light

2922299090

Bulk Drug Intermediates

46.2

0.04

White to cream Crystalline Powder

1.21g/cm3

189.6-190.2 °C

284 °C

189 °C

1.5764 (20ºC)

H2O: 1.5 g/100 mL (20 ºC);slightly soluble

Refrigerator

4.0X10-5 mm Hg at 25 deg C

Oral-rat LD50: 375 mg/kg; Abdominal cavity-mouse LDL0: 100 mg/kg

Open flame flammable; decomposed by heat; burning releases toxic nitrogen oxide fumes

Henry's Law constant = 3.6X10-10 atm-cu m/mole at 25 °C (est)

pK1 = 5.48 at 25 °C (conjugate acid)|pK2 = 10.46

Heat of formation = -190.6 kJ/mol|4-Aminophenol crystals exist in two forms. The less stable beta form (from acetone) exists as acicular crystals that turn into the alpha form on standing; they are orthorhombic bipyramidal or pyramidal /beta-4-Aminophenol/|Crystalline powder; gradually becomes darker. Decomposes about 306 °C. Very soluble in water; soluble in alcohol /p-Aminophenol hydrochloride/|Hydroxyl radical reaction rate constant = 7.4X10-11 cu cm/molecule-sec at 25 °C (est)

Insoluble in water.

Phenols and Cresols

Heat (decomposition forming HCN, nitrous vapors, CO); water (CO2); reacts violently with acids, bases, alcohols and amines causing fire and explosion hazards [Handling Chemicals Safely 1980 p. 647].