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  Product Detail  

1. Samaglutide Product Introduction

   I. Basic Information
   Name: Samaglutide
   CAS No.: 910463-68-2
   Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉
   Molecular Weight: 4113.58 Da
   Structure: Long-acting GLP-1 receptor agonist, fatty acid modified, half-life approximately 7 days

   Appearance: White lyophilized powder
   Purity: ≥99% (HPLC-MS)

   II. Mechanism of Action (GLP-1 monoreceptor agonist)
   Glucose Control: Glucose-dependent insulinotropic effect, glucagon inhibition
   Weight Loss: Delays gastric emptying, potent appetite suppression, reduces calorie intake
   Cardiovascular Protection: Reduces the risk of major adverse cardiovascular events 

   III. Core Efficacy
   Weight Loss 
   STEP 1: Average weight loss over 68 weeks 14–15% (approximately 15.5 kg)

   Over 80% fat loss, muscle preservation

   Blood sugar reduction 

   Type 2 diabetes: HbA1c reduction of 1.5–2.0%

   Improved metabolism

   Benefits include lowering blood pressure, improving blood lipids, and reducing fatty liver

   Cardiovascular benefits

   SELECT trial: 20% reduction in MACE risk in overweight/obese individuals

   
   
   
   
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