3-O-Ethyl-L-ascorbic acid (Vitamin C Ethyl Ether)

CAS No: 86404-04-8 (Word count: 498)

3-O-Ethyl-L-ascorbic acid, commonly known as Vitamin C Ethyl Ether, is a high-stability modified derivative of L‑ascorbic acid, widely recognized as a premium cosmetic active ingredient. Its molecular formula is C₈H₁₂O₆ with a molecular weight of 204.18 g/mol. The ethyl group attached to the 3-position of the ascorbic acid molecule protects the oxidation-sensitive site, solving the core drawbacks of pure vitamin C such as easy yellowing, rapid deactivation and strict low-pH requirements, while fully retaining the biological activity of vitamin C.

This raw material appears as white to off-white crystalline powder. It features amphiphilic solubility, dissolving in both water and oil phases, which enables flexible addition into various emulsion systems without complicated formulation adjustment. After penetrating the stratum corneum and entering the dermis, it will be converted into active L‑ascorbic acid via endogenous skin enzymes, delivering high bioavailability with mild skin irritation compared with pure vitamin C.

Functionally, it inhibits tyrosinase activity to block melanin biosynthesis, effectively fading dark spots, post-inflammatory pigmentation and uneven dull skin tone for brightening effects. It serves as a powerful antioxidant to neutralize free radicals induced by UV radiation, blue light and environmental pollutants, relieving sun-caused redness and photodamage. Besides, it stimulates fibroblast cells to synthesize collagen and elastin, improving skin elasticity, reducing fine lines and sagging for anti-ageing purposes. It also shows mild anti-inflammatory properties to soothe irritated skin and support barrier recovery.

It fits a broad pH range from 3.0 to 6.0, compatible with most cosmetic raw materials including peptides and plant extracts. Recommended dosage in finished cosmetics ranges from 0.5% to 5%. It is extensively applied in brightening serums, facial lotions, anti-ageing creams, sun care products, after-sun repair items and facial masks. Our product is manufactured under strict quality control, with HPLC purity ≥99%, low heavy metal content and stable batch consistency. Proper storage in cool, dry and sealed conditions can guarantee long shelf life, making it a preferred active ingredient for high-end skincare brands globally.