ss-31 2s50 Adequate inventory Exclusive offerFactory direct Best value
TDS 55 Inquiries
946870-92-4
Pharmaceutical Grade
99%
shenzhen
SH
vials
Yes
2027-12-31
Retatrutide,Acetic acid water,Tirzepatide
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceLong arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence ("arginine 3"), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) ("long"), for a total of 83 amino acids (relative to the 70 of IGF-1).Certificates
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TDS
Basic Info-
Product Name:
IGF-1 LR3
Other Name:IGF-1 LR3;CL281;LR3-IGF1;IGF-1Lr3 Igtropin;LR3-IGF1 (100mcg/vial;IGF LR3-1;IDF-1 LR3;Recombinant Human Insulin-like Growth Factor-1 LR3, rhIGF-1
CAS No.:946870-92-4
Molecular Weight:0
EC Number:1592732-453-0
Categories:
Research-
Class:
Mitochondria-targeted tetrapeptide (Szeto-Schiller peptide)
Status:FDA-approved (Forzinity) — Accelerated Approval 2025
Mechanism:A cell-permeable, synthetic tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) that selectively concentrates in the inner mitochondrial membrane and reversibly binds to cardiolipin, a phospholipid essential for electron transport chain (ETC) function. By stabilizing cardiolipin, SS-31 restores mitochondrial bioenergetics, reduces cytochrome c peroxidase activity, and prevents oxidative damage in cells with impaired mitochondrial function.
Activity note:SS-31 does not act via traditional receptor agonism. It binds cardiolipin with high selectivity in the inner mitochondrial membrane. Functional EC₅₀ values are context-dependent (cell type, stress model). Key electrophysiology studies report mitochondrial membrane potential restoration at nanomolar concentrations.
Source:Szeto HH, et al. AAPS J. 2006;8(2):E277-E283. Birk AV, et al. J Am Soc Nephrol. 2014;25(6):1157-1169.DOI
Clinical Development:FDA:Forzinity (approved 2025-09-19)
References-
ChEMBL:DrugBank:KEGG DRUG:PubChem:Literature:
FDA: Forzinity (NDA 215244) — Accelerated Approval 2025; Genetics in Medicine: TAZPOWER Phase 2/3 results (Thompson et al. 2020); Drugs: Elamipretide First Approval (Springer 2025)
Disclaimer:Elamipretide (Forzinity) is FDA-approved under accelerated approval for Barth syndrome. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.
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Seller Information
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Business Type:
Trader
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Main Products:
Retatrutide,Acetic acid water,Tirzepatide
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Location:
Room 2701-A046,Building 2,No.76 Lianyungang Road,Shibei District,Qingdao City,Shandong Province,P.R.China
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Year of Establishment:
2023
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Inquiry History55 Inquiries
Country Product Purchase Quantity Date Posted
United States
Best price Pure 98% LR3-IGF1 peptide IGF1 LR3 cas 946870-92-4
10 MT May 3, 2026
United States
Wholesale 99% High Purity IGF-1 LR3 Lyophilized Powder CAS 946870-92-4 Factory Direct Supply
10 PCS Apr 9, 2026
France
IGF-1 LR3 High Purity Ig F-Lr3 Peptides Powder CAS 946870-92-4 with Competitive Price
5 Nov 1, 2023
United States
YM 2024 High Quality Wholesale Price Peptides Factory Direct Supply IGF-1LR3 Powder CAS 946870-92-4
1111 MT Dec 18, 2025
Russia
igf-1 lr3
1 G Apr 22, 2025
Russia
Igf Lr3
10 MG Jun 6, 2026
United States
IGF-1 LR3
1 MT May 31, 2026
Canada
IGF-1 LR3
1 MG Mar 15, 2026
United States
IGF-1 LR3
10 MT Feb 23, 2026
United Kingdom
IGF-1 LR3
2 PCS Jan 21, 2026
Brazil
IGF-1 LR3
2 MG Jan 4, 2026
Canada
IGF-1R3
10 Dec 9, 2025
United States
Igf1 lr3
10 G Oct 16, 2024
Croatia
Igf-1 lr3
1 MT Oct 2, 2024
United States
IGF1-LR3
7.5 Feb 11, 2024
Switzerland
IGF-LR3 Recombinant Human IGF-1 LR3 99%
20 Jul 29, 2026
United States
IGF-1 LR3
40 MG Aug 31, 2026
United States
Igf-1lr3
10 MT Jul 20, 2026
United States
IGF-1LR3
1 G Jun 22, 2026
South Korea
igf lr3
10 G Jun 16, 2026 Post an enquiry for this product
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