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Mots-c(

141 Inquiries

Unit Price:

$64/MT FOB

Get Latest Price
CAS No.:

1627580-64-6

Grade:

Industrial Grade

Content:

99%

Port:

Tianjin

Packaging:

boxed

Price valid (until):

2026-11-13

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
11 days
Qualification:
Main Products:

Peptide

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Mechanism of Action


    Mots-C is a peptide derived from mitochondria that regulates energy metabolism at the cellular level. It primarily activates AMPK (AMP-activated protein kinase), a key enzyme that controls energy balance and cellular metabolism.

    1. Mitochondrial Energy Regulation: Mots-C activates AMPK, enhancing mitochondrial biogenesis and improving cellular energy production. This leads to better energy utilization and improved overall metabolic efficiency.

    2. Fat and Glucose Metabolism: By activating AMPK, Mots-C promotes fat oxidation, increases fat burning, and helps improve glucose uptake in tissues. This mechanism supports weight loss, enhances insulin sensitivity, and helps in managing obesity and insulin resistance.

    3. Muscle Preservation: Mots-C supports muscle protein synthesis, which helps preserve lean muscle mass, especially during periods of aging, intense exercise, or caloric restriction. It also promotes muscle recovery after physical stress.

    4. Anti-Aging: Through its mitochondrial activity, Mots-C reduces oxidative stress, helping to protect cells from damage associated with aging. This makes it a valuable agent for improving overall cellular health and longevity.


    Indications


    1. Metabolic Diseases: Mots-C has been shown to improve insulin sensitivity and regulate glucose metabolism, making it effective in managing type 2 diabetes and other metabolic disorders.

    2. Obesity and Weight Management: Mots-C is a powerful tool for promoting fat loss and managing obesity by enhancing fat burning and improving energy expenditure. It can help reduce visceral fat and improve body composition.

    3. Anti-Aging: Mots-C has anti-aging properties, enhancing mitochondrial function, reducing oxidative stress, and protecting cells from age-related decline. It supports cellular rejuvenation and longevity.

    4. Muscle Preservation and Recovery: Mots-C promotes muscle repair and prevents muscle loss during aging or periods of weight loss, making it beneficial for individuals looking to maintain lean muscle mass and improve recovery.


    Clinical Efficacy


    In clinical studies, Mots-C has shown significant potential in improving metabolic function, enhancing fat metabolism, and supporting muscle health. Its anti-aging effects have also been widely researched.

    1. Improved Metabolic Health: Clinical trials have demonstrated that Mots-C can improve insulin sensitivity, promote glucose metabolism, and reduce blood sugar levels, making it a promising treatment for type 2 diabetes and insulin resistance.

    2. Fat Loss and Body Composition: Studies have indicated that Mots-C can enhance fat oxidation, leading to a reduction in fat mass, particularly visceral fat. This makes it a potent agent for managing obesity and promoting healthy weight loss.

    3. Muscle Preservation: Mots-C is shown to preserve lean muscle mass by promoting muscle protein synthesis and reducing muscle breakdown. This makes it valuable for athletes, elderly individuals, and those undergoing caloric restriction.

    4. Anti-Aging Effects: Through its ability to improve mitochondrial function and reduce oxidative stress, Mots-C has demonstrated significant anti-aging effects in preclinical studies. It helps protect cells from oxidative damage, slowing down the aging process at the cellular level.


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    MOTS-c benefits


    MOTS-c is a mitochondrial-derived peptide that has gained attention in scientific research for its potential role in metabolic regulation and cellular energy balance. It is believed to influence how cells produce and utilize energy, making it an important focus in studies related to aging, metabolism, and physical performance.


    One of the main benefits observed in research is its possible effect on metabolic health. MOTS-c may help improve insulin sensitivity and support glucose utilization, which is why it is being studied in the context of metabolic disorders such as insulin resistance.


    Another key area of interest is its role in energy production and endurance. MOTS-c is thought to activate pathways that enhance mitochondrial function, helping cells produce energy more efficiently. This has led to research exploring its potential impact on physical performance and fatigue resistance.


    It is also being studied for its possible involvement in weight and fat metabolism regulation. By influencing how the body processes nutrients and stores energy, it may contribute to improved metabolic balance in experimental models.

    Additionally, MOTS-c is associated with cellular stress response and aging research, as it may help cells adapt to metabolic stress conditions and maintain function over time.


    Overall, MOTS-c is considered a promising research peptide in the fields of metabolism, energy regulation, and longevity science, though its effects in humans are still under investigation.


    What does the MOTS-c peptide do?


    MOTS-c is a mitochondrial-derived peptide that plays an important role in regulating cellular energy metabolism and stress response. It is naturally encoded within mitochondrial DNA and is released in response to metabolic stress, helping the body adapt to changing energy demands.


    One of its primary functions is supporting glucose and insulin regulation. Research suggests that MOTS-c may improve insulin sensitivity and enhance how cells utilize glucose for energy. This makes it a key focus in studies related to metabolic health and conditions such as insulin resistance.


    MOTS-c is also associated with enhancing mitochondrial function, which is essential for energy production in cells. By influencing mitochondrial signaling pathways, it may help increase energy efficiency and reduce cellular fatigue, particularly under conditions of physical or metabolic stress.


    Another important area of research is its potential role in fat metabolism and weight regulation. MOTS-c may help the body better balance energy intake and expenditure, supporting improved metabolic flexibility in experimental models.

    In addition, it is studied for its involvement in the cellular stress response, where it may help cells adapt to stressors such as exercise, fasting, or aging-related metabolic decline.


    Overall, MOTS-c is considered a promising peptide in research focused on metabolism, energy production, and longevity, although its effects in humans are still being studied and not yet fully confirmed clinically.


    Can I take MOTS-c every day?


    MOTS-c is a mitochondrial-derived peptide that is currently only studied in preclinical and early research settings, and its long-term safety in humans has not been fully established. Because of this, there are no approved medical guidelines or standardized recommendations for daily use.


    In laboratory studies, MOTS-c has shown interesting effects on metabolic regulation, insulin sensitivity, and cellular energy balance, but these findings are primarily based on animal or cell research. Human clinical data is still very limited, which means the long-term impact of repeated or daily administration is not well understood.


    Since it is not an FDA-approved drug or supplement, taking MOTS-c every day carries unknown risks, including potential effects on metabolism, hormonal balance, or cellular signaling pathways over time. Without controlled clinical trials, it is impossible to confirm whether daily use is safe or appropriate.


    Researchers generally treat MOTS-c as an experimental peptide, used under controlled conditions rather than as a routine daily compound. Its effects can vary depending on dosage, frequency, and individual biological response.

    Overall, while MOTS-c shows promising research potential in energy metabolism and aging studies, daily use in humans is not medically established or recommended. More clinical research is needed before safe long-term dosing guidelines can be determined.

    ECHEMI Editorial Reference

    MOTS-c is a 16-amino-acid mitochondria-derived peptide encoded by a short open reading frame within the mitochondrial 12S rRNA region. It is associated with the folate-AICAR-AMPK signaling pathway and has been studied for its role in cellular metabolic regulation. As a peptide research and pharmaceutical raw material, MOTS-c is suitable for biochemical research, analytical studies, and pharmaceutical development.


    MOTS-C Synthetic is a single, non-glycosylated polypeptide chain containing 16 amino acids, having a molecular mass of 2174.59 Dalton and a Molecular formula of C10H152N280O22 S2.

    Basic Info
    Product Name:

    MOTS-c

    Other Name:

    MOTS-c;L-Arginine, L-methionyl-L-arginyl-L-tryptophyl-L-glutaminyl-L-α-glutamyl-L-methionylglycyl-L-tyrosyl-L-isoleucyl-L-phenylalanyl-L-tyrosyl-L-prolyl-L-arginyl-L-lysyl-L-leucyl-;MOTS-C acetate;Cosmetic Peptide Mots-C;MOTS-c POWDER;MOTS-c peptide;MOTS-c 5mg/10mg;H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH

    CAS No.:

    1627580-64-6

    Molecular Formula:

    C101H152N28O22S2

    InChIKeys:

    WYTHCOXVWRKRAH-JIJBDQHHNA-N

    Molecular Weight:

    2174.62

    Exact Mass:

    2174.1110958

    EC Number:

    200-001-8

    Color/Form:

    Solid lyophilized powder

    Categories:

    Polypeptide

    Characteristics
    Density:

    1.44±0.1 g/cm3(Predicted)

    Critical Temperature & Pressure:

    Store at -20°C

    Research
    Class:

    Mitochondrial-derived peptide (MDP), 16-amino-acid peptide

    Status:

    Research compound — Not FDA approved

    Mechanism:

    MOTS-c (mitochondrial ORF of the twelve S rRNA-c) is a 16-amino-acid peptide encoded by the mitochondrial genome (not nuclear DNA). It is a mitochondrial-derived peptide that regulates metabolic homeostasis by activating the AMPK/PGC-1\u03b1 pathway, improving insulin sensitivity, and enhancing exercise capacity. MOTS-c crosses the blood-brain barrier and has been shown to reduce body weight and improve glucose tolerance in preclinical models.

    Activity note:

    MOTS-c does not act via a traditional receptor. It functions as a metabolic regulator, activating AMPK. Functional effects are observed at micromolar concentrations in cell-based assays.

    Source:

    Lee C, et al. Cell Metab. 2015;21(3):443-454. MCE: MOTS-c (CAS 1627580-64-6).DOI

    References
    PubChem:

    PubChem

    Disclaimer:

    MOTS-c is NOT FDA-approved or EMA-approved. It is a research compound only. All data are from preclinical (cell/animal) studies; no human clinical trials have been completed. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptide

    Location:

    Room 1501, Building 1, Changnan Mansion, Country Garden, on the west side of Taoyang North Road

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    11 days

    Year of Establishment:

    2025

  • Inquiry History
    141 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Mots-C CAS 1627580-64-6

    5 G Apr 26, 2026
    United States

    Bodygrowth Peptides CAS 1627580-64-6 MOTS-c (Human) Acetate peptides powder

    1 G Feb 23, 2026
    United States

    MOTS-c (Human) Acetate peptides powder

    1 G Mar 12, 2026
    Brazil

    MOTS-c 10mg Peptide Raw Material High Purity

    10 PCS Feb 17, 2026
    United States

    Mots-C

    1 KG Sep 12, 2025
    United States

    MOTS-c

    1 MG Oct 13, 2026
    Philippines

    MOTS-c

    20 MG Sep 28, 2026
    United States

    MOTS-c

    1 G Sep 11, 2026
    United States

    mots-c

    40 MG Aug 5, 2026
    United States

    Mots-c

    5 G Aug 3, 2026
    United States

    MOTS-c

    15 MG Jul 14, 2026
    Netherlands

    Mots-C 20mg

    40 MT Jul 8, 2026
    United States

    Mots-c

    1 G Jun 11, 2026
    Australia

    Mots-C

    1 KG Jun 9, 2026
    United States

    Mots-c 40mg

    10 PCS May 20, 2026
    United States

    Mots-c

    100 G May 19, 2026
    United States

    Mots-c

    1000 MG May 3, 2026
    United States

    MOTS-C

    400 MG May 1, 2026
    United States

    Mots-c

    1 G Apr 24, 2026
    United States

    Mots-c

    1000 KG Apr 24, 2026
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