Semaglutide API CAS 910463-68-2 | 99%+ High Purity Pharmaceutical Grade Peptide API Supplier & Manufacturer
COA TDS 26 Inquiries
1208243-50-8
Pharma Grade / Research Grade
99.9%
GUANGZHOU
HF
bottle
Yes
2026-11-15
peptides
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Product Description
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Seller Information
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History Price
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Inquiry History
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DescriptionECHEMI Editorial ReferenceCibinetide, also known as ARA-290, is a synthetic 11-mer peptide that binds the tissue-protective receptor. ARA290 inhibits high glucose-induced apoptosis of NRK-52E cells. Cibinetide Protects Isolated Human Islets in a Stressful Environment and Improves Engraftment in the Perspective of Intra Portal Islet Transplantation. Cibinetide Improves Corneal Nerve Fiber Abundance in Patients With Sarcoidosis-Associated Small Nerve Fiber Loss and Neuropathic Pain. ARA 290 relieves pathophysiological pain by targeting TRPV1 channel: Integration between immune system and nociception.CertificatesBasic Info
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Product Name:
Cibinetide
Other Name:ARA-290 (Cibinetide);ARA290, >98%;ARA290,Cibinetide, >98%;ARA290;WZTIQQBMSJTRBR-MUZUOSMHSA-N;ara290/Poziotinib;L-Serine, 5-oxo-L-prolyl-L-α-glutamyl-L-glutaminyl-L-leucyl-L-α-glutamyl-L-arginyl-L-alanyl-L-leucyl-L-asparaginyl-L-seryl-;ARA-290(Cibinetide) acetate
CAS No.:1208243-50-8
Molecular Formula:C51H84N16O21
InChIKeys:WZTIQQBMSJTRBR-WYKNNRPVSA-N
Molecular Weight:1257.31
EC Number:200-001-8
Color/Form:White to off-white
Categories:
Characteristics-
Density:
1.56±0.1 g/cm3(Predicted)
PKA:2.90±0.10(Predicted)
Research-
Class:
GLP-1R agonist
Status:FDA-approved (Ozempic / Wegovy / Rybelsus)
Mechanism:Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.
Activity note:Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).
Source:Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI
Clinical Development:FDA:Ozempic, Wegovy, Rybelsus (approved 2017-12-05)
References-
ChEMBL:DrugBank:KEGG DRUG:PubChem:Literature:
NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)
Disclaimer:Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.
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Seller Information
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Business Type:
Trader
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Main Products:
peptides
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Location:
No. 85, Qingnian Road, Hongqiao District, Tianjin
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2026
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Weekly Price
The chart shows the price trend of the product in the past 12 months.
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Inquiry History26 Inquiries
Country Product Purchase Quantity Date Posted
United States
Factory Supply 99% Purity Ara 290 Peptides Raw Lyophilized Powder CAS 1208243-50-8
1 G Oct 29, 2023
United States
ARA-290
15 MG Aug 3, 2026
United States
ARA 290
1 G Apr 13, 2026
United States
ARA-290 Peptide
1 G Feb 6, 2026
United States
ARA-290
10 PCS Nov 15, 2025
Thailand
Cibinetide
200 KG May 10, 2025
Lithuania
ARA 290
60 Nov 28, 2023
United States
Ara 290
100 MG Aug 4, 2026
United States
ARA-290 10mg
100 PCS Apr 17, 2026
United States
ARA-290
10 MT May 10, 2024
Denmark
Cibinetide
5 G Feb 11, 2024
Lithuania
ARA 290
10 Nov 28, 2023
United States
Ara-290
5 PCS Oct 10, 2026
United Kingdom
ARA-290
20 MG Sep 29, 2026
Philippines
I am looking for Ara 290 100 vials
30 MT Aug 5, 2026
United States
Ara-290
20 MG Jul 20, 2026
United States
ARA 290
1 KG Jun 15, 2026
Belgium
ARA290
1 KG May 20, 2026
United States
Reta
60 May 4, 2026
United States
ARA-290 Lyophilized
800 MG Apr 17, 2026 Post an enquiry for this product
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