Product Overview

Methyl 2-(bromomethyl)benzoate is an organic compound with the molecular formula C₉H₉BrO₂ and molecular weight of 229.07 g/mol. This white to off-white crystalline solid is a valuable intermediate in pharmaceutical and organic synthesis research. The compound features a bromomethyl group at the 2-position and a methyl ester group on the benzene ring.

Synthetic Process

• Bromination: Methyl 2-methylbenzoate is brominated using elemental bromine or NBS in the presence of a catalyst to yield the bromomethyl derivative

• Purification: The crude product is purified by recrystallization from suitable solvents

• Drying: The purified product is dried under vacuum

Mechanism of Action

• Benzylic Reactivity: The benzylic bromide can undergo nucleophilic substitution reactions

• Ester Functionalization: The methyl ester can be hydrolyzed to the corresponding carboxylic acid or reduced to the alcohol

• Lactone Formation: The bromomethyl and ester groups can participate in intramolecular cyclization reactions

Research Applications & Market Significance

• Pharmaceutical Research: Building block for drug discovery programs

• Organic Synthesis: Versatile intermediate for functionalized benzoate derivatives

• Agrochemical Synthesis: Intermediate for pesticide development

• Material Science: Used in the preparation of specialty polymers

Quality Specifications

• Purity: ≥98.0% determined by GC

• Melting point: 48-51°C

• Boiling point: 145-147°C (10 mmHg)

• Loss on drying: ≤0.5%

• Storage: 2-8°C, sealed, protected from light

• Stable for 24 months when properly stored

Packaging & Shipping

• Research quantities: 25g, 100g amber glass bottles

• Bulk quantities: 500g, 1kg amber glass bottles

• Shipped at ambient temperature